Search Results - "Ainsa, José Antonio"

Design, synthesis and inhibitory activity against Mycobacterium tuberculosis thymidine monophosphate kinase of acyclic nucleoside analogues with a distal imidazoquinolinone by Familiar, Olga, Munier-Lehmann, Hélène, Aínsa, José Antonio, Camarasa, María-José, Pérez-Pérez, María-Jesús

“…Thymidine monophosphate kinase from Mycobacterium tuberculosis (TMPKmt) has been proposed as an attractive target in the search of new agents to fight against…”
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In silico discovery and biological validation of ligands of FAD synthase, a promising new antimicrobial target by Lans, Isaias, Anoz-Carbonell, Ernesto, Palacio-Rodriguez, Karen, Ainsa, Jose Antonio, Medina, Milagros, Cossio, Pilar

“…New treatments for diseases caused by antimicrobial-resistant microorganisms can be developed by identifying unexplored therapeutic targets and by designing…”
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In vitro synergy screens of FDA-approved drugs reveal novel zidovudine- and azithromycin-based combinations with last-line antibiotics against Klebsiella pneumoniae by Gómara-Lomero, Marta, López-Calleja, Ana Isabel, Rezusta, Antonio, Aínsa, José Antonio, Ramón-García, Santiago

“…Treatment of infections caused by multi-drug resistant (MDR) enterobacteria remains challenging due to the limited therapeutic options available. Drug…”
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Design, Synthesis, and Efficacy Testing of Nitroethylene- and 7‑Nitrobenzoxadiazol-Based Flavodoxin Inhibitors against Helicobacter pylori Drug-Resistant Clinical Strains and in Helicobacter pylori-Infected Mice by Salillas, Sandra, Alías, Miriam, Michel, Valérie, Mahía, Alejandro, Lucía, Ainhoa, Rodrigues, Liliana, Bueno, Jessica, Galano-Frutos, Juan José, De Reuse, Hilde, Velázquez-Campoy, Adrián, Carrodeguas, José Alberto, Sostres, Carlos, Castillo, Javier, Aínsa, José Antonio, Díaz-de-Villegas, María Dolores, Lanas, Ángel, Touati, Eliette, Sancho, Javier

“…Helicobacter pylori (Hp) infection is the main cause of peptic ulcer and gastric cancer. Hp eradication rates have fallen due to increasing bacterial…”
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Total Synthesis of Ripostatin B and Structure–Activity Relationship Studies on Ripostatin Analogs by Glaus, Florian, Dedić, Darija, Tare, Priyanka, Nagaraja, Valakunja, Rodrigues, Liliana, Aínsa, José Antonio, Kunze, Jens, Schneider, Gisbert, Hartkoorn, Ruben C, Cole, Stewart T, Altmann, Karl-Heinz

“…Described is the total synthesis of the myxobacterial natural product ripostatin B and of a small number of analogs. Ripostatin B is a polyketide-derived…”
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Merging multi-omics with proteome integral solubility alteration unveils antibiotic mode of action by Maity, Ritwik, Zhang, Xuepei, Liberati, Francesca Romana, Scribani Rossi, Chiara, Cutruzzolá, Francesca, Rinaldo, Serena, Gaetani, Massimiliano, Aínsa, José Antonio, Sancho, Javier

“…Antimicrobial resistance is responsible for an alarming number of deaths, estimated at 5 million per year. To combat priority pathogens, like , the development…”
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Discovery of antimicrobial compounds targeting bacterial type FAD synthetases by Sebastián, María, Anoz-Carbonell, Ernesto, Gracia, Begoña, Cossio, Pilar, Aínsa, José Antonio, Lans, Isaías, Medina, Milagros

“…The increase of bacterial strains resistant to most of the available antibiotics shows a need to explore novel antibacterial targets to discover antimicrobial…”
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Antimicrobial combinations against Helicobacter pylori including benzoxadiazol-based flavodoxin inhibitors: in vitro characterization by Beyria, Lilha, Gourbeyre, Ophelie, Salillas, Sandra, Mahía, Alejandro, Díaz de Villegas, María Dolores, Aínsa, José Antonio, Sancho, Javier, Bousquet-Mélou, Alain, Ferran, Aude A

“…The antimicrobial resistance of ( ) currently poses a threat to available treatment regimens. Developing antimicrobial drugs targeting new bacterial targets is…”
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Matryoshka-type gastro-resistant microparticles for the oral treatment of Mycobacterium tuberculosis by Andreu, Vanesa, Larrea, Ane, Rodriguez-Fernandez, Pablo, Alfaro, Salvador, Gracia, Begoña, Lucía, Ainhoa, Usón, Laura, Gomez, Andromeda-Celeste, Mendoza, Gracia, Lacoma, Alicia, Dominguez, Jose, Prat, Cristina, Sebastian, Victor, Ainsa, José Antonio, Arruebo, Manuel

“…Production of Matryoshka-type gastroresistant microparticles containing antibiotic-loaded poly lactic-co-glycolic acid (PLGA) nanoparticles (NP) against…”
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Ionophore A23187 shows anti-tuberculosis activity and synergy with tebipenem by Huang, Wei, Briffotaux, Julien, Wang, Xinwei, Liu, Lili, Hao, Pei, Cimino, Mena, Buchieri, Maria Virginia, Namouchi, Amine, Ainsa, Jose-Antonio, Gicquel, Brigitte

“…The objective of this study was to find molecules with anti-mycobacterial activity from a natural compounds library, investigate their mechanisms of…”
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L-Thyroxine and L-thyroxine-based antimicrobials against Streptococcus pneumoniae and other Gram-positive bacteria by Galano-Frutos, Juan José, Maity, Ritwik, Iguarbe, Verónica, Aínsa, José Antonio, Velázquez-Campoy, Adrián, Schaible, Ulrich E., Mamat, Uwe, Sancho, Javier

“…The rise of antibiotic-resistant Streptococcus pneumoniae (Sp) poses a significant global health threat, urging the quest for novel antimicrobial solutions. We…”
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Matryoshka-type gastro-resistant microparticles for the oral treatment of by Andreu, Vanesa, Larrea, Ane, Rodriguez-Fernandez, Pablo, Alfaro, Salvador, Gracia, Begoña, Lucía, Ainhoa, Usón, Laura, Gomez, Andromeda-Celeste, Mendoza, Gracia, Lacoma, Alicia, Dominguez, Jose, Prat, Cristina, Sebastian, Victor, Ainsa, José Antonio, Arruebo, Manuel

“…Production of Matryoshka-type gastroresistant microparticles containing antibiotic-loaded poly lactic- -glycolic acid (PLGA) nanoparticles (NP) against . The…”
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Transcriptional analysis of and resistance level conferred by the aminoglycoside acetyltransferase gene aac(2′)-Id from Mycobacterium smegmatis by Mick, Virginie, Rebollo, María José, Lucía, Ainhoa, García, María Jesús, Martín, Carlos, Aínsa, José Antonio

“…Objectives To analyse the correlation between the expression levels of the aac(2′)-Id gene from Mycobacterium smegmatis mc2155 and the resistance levels to…”
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The EU approved antimalarial pyronaridine shows antitubercular activity and synergy with rifampicin, targeting RNA polymerase by Mori, Giorgia, Orena, Beatrice Silvia, Franch, Clara, Mitchenall, Lesley A., Godbole, Adwait Anand, Rodrigues, Liliana, Aguilar-Pérez, Clara, Zemanová, Júlia, Huszár, Stanislav, Forbak, Martin, Lane, Thomas R., Sabbah, Mohamad, Deboosere, Nathalie, Frita, Rosangela, Vandeputte, Alexandre, Hoffmann, Eik, Russo, Riccardo, Connell, Nancy, Veilleux, Courtney, Jha, Rajiv K., Kumar, Pradeep, Freundlich, Joel S., Brodin, Priscille, Aínsa, Jose Antonio, Nagaraja, Valakunja, Maxwell, Anthony, Mikušová, Katarína, Pasca, Maria Rosalia, Ekins, Sean

“…The search for compounds with biological activity for many diseases is turning increasingly to drug repurposing. In this study, we have focused on the European…”
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Merging multi-omics with proteome integral solubility alteration unveils antibiotic mode of action by Maity, Ritwik, Zhang, Xuepei, Liberati, Francesca Romana, Scribani Rossi, Chiara, Cutruzzolá, Francesca, Rinaldo, Serena, Gaetani, Massimiliano, Aínsa, José Antonio, Sancho, Javier

“…Antimicrobial resistance is responsible for an alarming number of deaths, estimated at 5 million per year. To combat priority pathogens, like Helicobacter…”
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Isolation by genetic labeling of a new mycobacterial plasmid, pJAZ38, from Mycobacterium fortuitum by Gavigan, J A, Aínsa, J A, Pérez, E, Otal, I, Martín, C

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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ll by Juan José Galano-Frutos, Ritwik Maity, Verónica Iguarbe, José Antonio Aínsa, Adrián Velázquez-Campoy, Ulrich E. Schaible, Uwe Mamat, Javier Sancho

“…Objectives: The rise of antibiotic-resistant Streptococcus pneumoniae (Sp) poses a significant global health threat, urging the quest for novel antimicrobial…”
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