Search Results - "Ainan, Bharathi Raja"

Discovery of CA-4948, an Orally Bioavailable IRAK4 Inhibitor for Treatment of Hematologic Malignancies by Gummadi, Venkateshwar Rao, Boruah, Anima, Ainan, Bharathi Raja, Vare, Brahma Reddy, Manda, Srinivas, Gondle, Hari Prakash, Kumar, Shiva Nagendra, Mukherjee, Subhendu, Gore, Suraj T, Krishnamurthy, Narasimha Rao, Marappan, Sivapriya, Nayak, Shilpa S, Nellore, Kavitha, Balasubramanian, Wesley Roy, Bhumireddy, Archana, Giri, Sanjeev, Gopinath, Sreevalsam, Samiulla, Dodheri S, Daginakatte, Girish, Basavaraju, Aravind, Chelur, Shekar, Eswarappa, Rajesh, Belliappa, Charamanna, Subramanya, Hosahalli S, Booher, Robert N, Ramachandra, Murali, Samajdar, Susanta

“…Small molecule potent IRAK4 inhibitors from a novel bicyclic heterocycle class were designed and synthesized based on hits identified from Aurigene’s compound…”
Get full text

Abstract 4798: Efficacy and safety of highly selective novel IRAK4 inhibitors for treatment of ABC-DLBCL by Balasubramanian, Wesley Roy, Gummadi, Venkateshwar Rao, Nellore, Kavitha, Mukherjee, Subhendu, Marappan, Sivapriya, Basavaraju, Aravind, Ainan, Bharathi Raja, Daginakatte, Girish, Gopinath, Sreevalsam, Giri, Sanjeev, Antony, Thomas, Chelur, Shekar, Samajdar, Susanta, Pandit, Chetan, Ramachandra, Murali

“…Abstract Interleukin-1 receptor associated kinases (IRAKs) are serine/threonine protein kinases belonging to the tyrosine-like kinase (TLK) family. IRAKs…”
Get full text

Abstract C191: Efficacy of novel IRAK4 inhibitors in ABC-DLBCL and AML models by Rao, Venkateshwar, Balasubramanian, Wesley Roy, Nellore, Kavitha, Marappan, Sivapriya, Basavaraju, Aravind, Raja Ainan, Bharathi, Daginakatte, Girish, Gopinath, Sreevalsam, Giri, Sanjeev, Antony, Thomas, Chelur, Shekar, Samajdar, Susanta, Pandit, Chetan, Ramachandra, Murali

“…Abstract Interleukin-1 receptor associated kinases (IRAKs) are serine/threonine protein kinases belonging to tyrosine-like kinase (TLK) family. The IRAK family…”
Get full text

Discovery of 7-azaindole based anaplastic lymphoma kinase (ALK) inhibitors: Wild type and mutant (L1196M) active compounds with unique binding mode by Gummadi, Venkateshwar Rao, Rajagopalan, Sujatha, Looi, Chung-Yeng, Paydar, Mohammadjavad, Renukappa, Girish Aggunda, Ainan, Bharathi Raja, Krishnamurthy, Narasimha Rao, Panigrahi, Sunil Kumar, Mahasweta, Kumari, Raghuramachandran, Sangeetha, Rajappa, Manoj, Ramanathan, Anuradha, Lakshminarasimhan, Anirudha, Ramachandra, Murali, Wong, Pooi-Fong, Mustafa, Mohammad Rais, Nanduri, Srinivas, Hosahalli, Subramanya

“…A novel series of 7-Azaindole derivatives have been identified as potent ALK inhibitors. Their synthesis and preliminary SAR are described. We have identified…”
Get full text