Search Results - "Aijuan Yan"

Exosomes Derived From M2 Microglia Cells Attenuates Neuronal Impairment and Mitochondrial Dysfunction in Alzheimer's Disease Through the PINK1/Parkin Pathway by Li, Nan, Shu, Jun, Yang, Xiaoyan, Wei, Wenshi, Yan, Aijuan

“…The accumulation of abnormal aggregation of amyloid-β plaques is one of the most distinguishing pathologies of Alzheimer's disease (AD) and is highly toxic to…”
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Association of Pre-stroke Frailty With Prognosis of Elderly Patients With Acute Cerebral Infarction: A Cohort Study by Yang, Fuxia, Li, Nan, Yang, Lu, Chang, Jie, Yan, Aijuan, Wei, Wenshi

“…BackgroundFrailty is a state of cumulative degradation of physiological functions that leads to adverse outcomes such as disability or mortality. Currently,…”
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Idebenone Alleviates Neuroinflammation and Modulates Microglial Polarization in LPS-Stimulated BV2 Cells and MPTP-Induced Parkinson's Disease Mice by Yan, Aijuan, Liu, Zhihua, Song, Lu, Wang, Xijin, Zhang, Yu, Wu, Na, Lin, Jingya, Liu, Ying, Liu, Zhenguo

“…Idebenone is an antioxidant and a coenzyme Q10 analog that has been used to treat neurodegeneration disease. Some studies show idebenone exerts…”
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Systemic Inflammation Increases the Susceptibility to Levodopa-Induced Dyskinesia in 6-OHDA Lesioned Rats by Targeting the NR2B-Medicated PKC/MEK/ERK Pathway by Yan, Aijuan, Song, Lu, Zhang, Yu, Wang, Xijin, Liu, Zhenguo

“…The long-term administration of levodopa (L-dopa), the gold-standard treatment for Parkinson's disease (PD), is irreparably associated with L-dopa-induced…”
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Thromboxane A2 receptor antagonist SQ29548 reduces ischemic stroke-induced microglia/macrophages activation and enrichment, and ameliorates brain injury by Yan, Aijuan, Zhang, Tingting, Yang, Xiao, Shao, Jiaxiang, Fu, Ningzhen, Shen, Fanxia, Fu, Yi, Xia, Weiliang

“…Thromboxane A2 receptor (TXA2R) activation is thought to be involved in thrombosis/hemostasis and inflammation responses. We have previously shown that TXA2R…”
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White matter hyperintensity mediating gait disorders in iNPH patients via neurofilament light chain by Yang, Lu, Yang, Fuxia, Deng, Yao, Yan, Aijuan, Wei, Wenshi, Fang, Xuhao

“…This study aimed to analyze the differences in regional white matter hyperintensities (WMH) volume and cerebrospinal fluid biomarker levels between idiopathic…”
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Effect of in vitro gastrointestinal digestion on the chemical composition and antioxidant properties of Ginkgo biloba leaves decoction and commercial capsules by Zhou, Yubo, Yang, Yingxin, Ma, Minyan, Xie, Lingyun, Yan, Aijuan, Cao, Wen

“…In this study leaves (GBL) decoction and commercial capsules were digested using an model. Thirty-six active compounds were identified and quantified by…”
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Partial Depletion of Peripheral M1 Macrophages Reverses Motor Deficits in MPTP-Treated Mouse by Suppressing Neuroinflammation and Dopaminergic Neurodegeneration by Yan, Aijuan, Zhang, Yu, Lin, Jingya, Song, Lu, Wang, Xijin, Liu, Zhenguo

“…Neuroinflammation plays an important role in the pathogenesis of Parkinson's disease (PD). Inflammatory cytokines in the peripheral immune system can induce…”
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Adjudin-preconditioned neural stem cells enhance neuroprotection after ischemia reperfusion in mice by Zhang, Tingting, Yang, Xiao, Liu, Tengyuan, Shao, Jiaxiang, Fu, Ningzhen, Yan, Aijuan, Geng, Keyi, Xia, Weiliang

“…Transplantation of neural stem cells (NSCs) has been proposed as a promising therapeutic strategy for the treatment of ischemia/reperfusion (I/R)-induced brain…”
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LC-MS/MS-based Quantification of Ten Neurotransmitters in Rat Limbic System and Serum: Application to Chronic Unpredictable Mild Stress- Induced Depression Rats by Mingyan Ma, Qiangxiang Chen, Wen Cao, Yubo Zhou, Aijuan Yan, Yanru Zhu

“…As one of the most common mood disorders, numerous studies have shown depression is the main risk factor for non-suicidal self-harm. The pathogenesis of…”
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Genetic analysis and clinical assessment of four patients with Glycogen Storage Disease Type IIIa in China by Zhang, Yu, Xu, Mingming, Chen, Xiaoxia, Yan, Aijuan, Zhang, Guoyong, Liu, Zhenguo, Qiu, Wenjuan

“…Glycogen Storage Disease Type III (GSD III) is a rare autosomal recessive metabolic disorder caused by AGL gene mutation. There is significant heterogeneity…”
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Oculomotor Performances Are Associated With Motor and Non-motor Symptoms in Parkinson's Disease by Zhang, Yu, Yan, Aijuan, Liu, Bingyu, Wan, Ying, Zhao, Yuchen, Liu, Ying, Tan, Jiangxiu, Song, Lu, Gu, Yong, Liu, Zhenguo

“…Parkinson's disease (PD) patients exhibit deficits in oculomotor behavior, yet the results are inconsistent across studies. In addition, how these results are…”
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LC-MS/MS-based Quantification of Ten Neurotransmitters in Rat Limbic System and Serum: Application to Chronic Unpredictable Mild Stress-Induced Depression Rats by Mingyan Ma, Qiangxiang Chen, Wen Cao, Yubo Zhou, Aijuan Yan, Yanru Zhu

“…As one of the most common mood disorders, numerous studies have shown depression is the main risk factor for non-suicidal self-harm. The pathogenesis of…”
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The association between precuneus cortex thickness and mild behavioral impairment in patients with mild stroke by Liu, Zhengxin, Xu, Ziwei, Yan, Aijuan, Zhang, Panpan, Wei, Wenshi

“…The objective of this research was to examine the association between precuneus cortex thickness and mild behavioral impairment (MBI) in patients with mild…”
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The p75 neurotrophin receptor as a novel intermediate in L-dopa-induced dyskinesia in experimental Parkinson's disease by Liu, Zhihua, Yan, Aijuan, Zhao, Jiahao, Yang, Shuyuan, Song, Lu, Liu, Zhenguo

“…In Parkinson's disease (PD), long-term administration of L-dopa often leads to L-dopa-induced dyskinesia (LID), a debilitating motor complication. The p75…”
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Optimization and characterization of Mytilus coruscus polysaccharide and investigation on antitumor activity by Ma, Mingyan, Zhou, Yubo, Zhang, Jiajia, Yan, Aijuan, Cao, Wen

“…This study aimed to optimize the enzymatic extraction of polysaccharides from Mytilus coruscus using the response surface method, characterize its composition,…”
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Increased Cerebrospinal Fluid Levels of Soluble Triggering Receptor Expressed on Myeloid Cells 2 and Chitinase-3-Like Protein 1 in Idiopathic Normal-Pressure Hydrocephalus by Yang, Fuxia, Yang, Lu, Fang, Xuhao, Deng, Yao, Mao, Renling, Yan, Aijuan, Wei, Wenshi

“…Neurodegenerative disease pathology is associated with neuroinflammation, but evidence on idiopathic normal pressure hydrocephalus (iNPH) remains limited and…”
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Thromboxane A2 receptor antagonist SQ29548 attenuates SH‑SY5Y neuroblastoma cell impairments induced by oxidative stress by Cai, Gaoyu, Yan, Aijuan, Fu, Ningzhen, Fu, Yi

“…Thromboxane A2 receptor (TXA2R) serves a vital role in numerous neurological disorders. Our previous study indicated that SQ29548, an antagonist of TXA2R,…”
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White matter hyperintensities-related cortical changes and correlation with mild behavioral impairment by Yang, Lu, Shu, Jun, Yan, Aijuan, Yang, Fuxia, Xu, Ziwei, Wei, Wenshi

“…The aim of this study was to analyze cortical thickness and gray matter volume (GMV) changes in white matter hyperintensities (WMH) which were associated brain…”
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In vitro bioaccessibility analysis and safety assessment of essential and toxic trace elements from ten herbal medicines widely used in China by Ma, Minyan, Yang, Yingxin, Yan, Aijuan, Cao, Wen, Zhou, Yubo

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