Search Results - "Aidagulova, Svetlana V"
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Proteoglycans as potential microenvironmental biomarkers for colon cancer
Published in Cell and tissue research (01-09-2015)“…Glycosylation changes occur widely in colon tumours, suggesting glycosylated molecules as potential biomarkers for colon cancer diagnostics. In this study,…”
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Dexamethasone Inhibits Heparan Sulfate Biosynthetic System and Decreases Heparan Sulfate Content in Orthotopic Glioblastoma Tumors in Mice
Published in International journal of molecular sciences (01-06-2023)“…Glioblastoma (GB) is an aggressive cancer with a high probability of recurrence, despite active chemoradiotherapy with temozolomide (TMZ) and dexamethasone…”
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3
Multiple Irradiation Affects Cellular and Extracellular Components of the Mouse Brain Tissue and Adhesion and Proliferation of Glioblastoma Cells in Experimental System In Vivo
Published in International journal of molecular sciences (12-12-2021)“…Intensive adjuvant radiotherapy (RT) is a standard treatment for glioblastoma multiforme (GBM) patients; however, its effect on the normal brain tissue remains…”
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4
Chemoradiotherapy Increases Intratumor Heterogeneity of HPSE Expression in the Relapsed Glioblastoma Tumors
Published in International journal of molecular sciences (14-02-2020)“…Adjuvant chemoradiotherapy is a standard treatment option for glioblastoma multiforme (GBM). Despite intensive care, recurrent tumors developed during the…”
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5
Multiple Administration of Dexamethasone Possesses a Deferred Long-Term Effect to Glycosylated Components of Mouse Brain
Published in Neurology international (22-07-2024)“…Glucocorticoids are used during glioblastoma treatment to prevent the cerebral edema effect surrounding normal brain tissue. The aim of our study was to…”
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Heparan Sulfate Biosynthetic System Is Inhibited in Human Glioma Due to EXT1/2 and HS6ST1/2 Down-Regulation
Published in International journal of molecular sciences (01-11-2017)“…Heparan sulfate (HS) is an important component of the extracellular matrix and cell surface, which plays a key role in cell-cell and cell-matrix interactions…”
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Chemotherapy-Induced Degradation of Glycosylated Components of the Brain Extracellular Matrix Promotes Glioblastoma Relapse Development in an Animal Model
Published in Frontiers in oncology (19-07-2021)“…Adjuvant chemotherapy with temozolomide (TMZ) is an intrinsic part of glioblastoma multiforme (GBM) therapy targeted to eliminate residual GBM cells. Despite…”
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Conventional Anti-glioblastoma Chemotherapy Affects Proteoglycan Composition of Brain Extracellular Matrix in Rat Experimental Model in vivo
Published in Frontiers in pharmacology (02-10-2018)“…Temozolomide (TMZ) is a conventional chemotherapy drug for adjuvant treatment of glioblastoma multiforme (GBM), often accompanied by dexamethasone (DXM) to…”
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Prognostic relevance of NG2/CSPG4, CD44 and Ki-67 in patients with glioblastoma
Published in Tumor biology (01-09-2017)“…Neuron-glial antigen 2 (NG2, also known as CSPG4) and hyaluronic acid receptor CD44 are chondroitin sulphate proteoglycans actively involved in brain…”
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Transcriptional Activity of Heparan Sulfate Biosynthetic Machinery is Specifically Impaired in Benign Prostate Hyperplasia and Prostate Cancer
Published in Frontiers in oncology (01-01-2014)“…Heparan sulfates (HSs) are key components of mammalian cells surface and extracellular matrix. Structure and composition of HS, generated by HS-biosynthetic…”
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Chondroitin sulfate content and decorin expression in glioblastoma are associated with proliferative activity of glioma cells and disease prognosis
Published in Cell and tissue research (2020)“…Chondroitin sulfate proteoglycans (CSPGs) are important components of brain extracellular matrix (ECM), although their contribution in gliomagenesis remains…”
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12
Suitability of RNALater solution as a tissue-preserving reagent for immunohistochemical analysis
Published in Histochemistry and cell biology (01-09-2019)“…Histological and immunohistochemical studies require high-quality paraffin blocks, where proper fixation of tissue samples with formalin is a key point…”
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Heparan sulfate accumulation and perlecan/HSPG2 up-regulation in tumour tissue predict low relapse-free survival for patients with glioblastoma
Published in Histochemistry and cell biology (01-03-2018)“…Glycosaminoglycans are major components of brain extracellular matrix (ECM), although heparan sulfate (HS) contribution in brain physiology and carcinogenesis…”
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14
Single X-ray irradiation modulates proteoglycan expression in brain tissue: investigation using mouse model
Published in Molecular biology reports (01-07-2020)“…Radiotherapy is an integral part of glioblastoma treatment affecting both cancer cells and tumour microenvironment, where proteoglycans (PGs) are key…”
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Prolonged use of temozolomide leads to increased anxiety and decreased content of aggrecan and chondroitin sulfate in brain tissues of aged rats
Published in Biomedical reports (01-01-2024)“…Chemotherapy with temozolomide (TMZ) is an essential part of anticancer therapy used for malignant tumors (mainly melanoma and glioblastoma); however, the…”
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Causative Role of Ureaplasma Urealyticum and other Sexually Transmitted Infections in the Urethral Meatus Polyp Development in Women
Published in International journal of biomedicine (01-09-2013)“…The objective of this study was the investigation of the influence of ureaplasmal infection on the development of urethral meatus polyps in women. The article…”
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Proteoglycan Expression in Normal Human Prostate Tissue and Prostate Cancer
Published in ISRN oncology (2013)“…Proteoglycans (PGs) are expressed on the cell surface and extracellular matrix of all mammalian cells and tissues, playing an important role in cell-cell and…”
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18
Association of polymorphic variants of cytokines genes, endothelial growth factor and matrix metalloproteinases with the development of uterine fibroids among russian women
Published in Sibirskiĭ nauchnyĭ medit︠s︡inskiĭ zhurnal (27-04-2024)“…One of the factors in the development of uterine fibroids is a genetic predisposition to its occurrence in some women, but the real molecular genetic…”
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Polymorphisms of candidate genes determining the clinical and hemostasiological characteristics of endocarditis of various etiology
Published in Bi͡u︡lletenʹ Sibirskoĭ medit͡s︡iny (12-04-2022)“…Aim . To investigate polymorphisms of 18 genes as possible molecular genetic markers of predisposition or resistance to development of non-infective (NE) or…”
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Systemic factors regulating of angiogenesis in multiple uterine fibroids
Published in Medit͡s︡inskai͡a︡ immunologii͡a (01-08-2019)“…Uterine leiomyomas (LM), or uterine fibroids (UF), are benign tumors of the uterus. Hypertrophic increase in muscle mass in LM is accompanied by the…”
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