Search Results - "Ai, Yanran"
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Zirconium/Nickel‐Mediated One‐Pot Ketone Synthesis
Published in Angewandte Chemie International Edition (28-08-2017)“…A zirconium/nickel‐mediated one‐pot synthesis of ketones is reported. In the presence of Zn or Mn, Cp2ZrCl2 was found to dramatically accelerate the coupling…”
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Journal Article -
2
Unified, Efficient, and Scalable Synthesis of Halichondrins: Zirconium/Nickel‐Mediated One‐Pot Ketone Synthesis as the Final Coupling Reaction
Published in Angewandte Chemie International Edition (28-08-2017)“…Unified, efficient, and scalable syntheses of the halichondrin natural products are reported. A newly developed Zr/Ni‐mediated one‐pot ketone synthesis was…”
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Journal Article -
3
Stereocontrolled Synthesis of Left Halves of Halichondrins
Published in Journal of organic chemistry (01-09-2017)“…A stereocontrolled synthesis of the left halves of halichondrins was reported. An intramolecular oxy-Michael reaction under basic conditions was used to…”
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4
Efficacy of extracorporeal shock waves in the treatment of myofascial pain syndrome: a systematic review and meta-analysis of controlled clinical studies
Published in Annals of translational medicine (01-02-2022)“…Myofascial pain syndrome (MPS) is recurrent local myofascial pain with various treatment methods. In recent years, extracorporeal shock wave therapy (ESWT) has…”
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5
Unified Synthesis of Right Halves of Halichondrins A–C
Published in Journal of organic chemistry (01-09-2017)“…The right halves of halichondrins A–C were synthesized by coupling the common C20–C37 building block 9 with the C1–C19 building blocks 10a–c, respectively…”
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6
Total Synthesis of (−)-Enigmazole A
Published in Journal of the American Chemical Society (16-12-2015)“…A highly convergent, stereocontrolled total synthesis of the architecturally complex marine sponge metabolite (−)-enigmazole A has been achieved. Highlights…”
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7
Preclinical Evaluation of INCB160058 - a Novel and Potentially Disease-Modifying Therapy for JAK2V617F Mutant Myeloproliferative Neoplasms
Published in Blood (02-11-2023)“…The Janus kinase 2 ( JAK2) mutation, JAK2V617F, is the most common oncogenic driver in myeloproliferative neoplasms (MPNs), with nearly all cases of…”
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Total Synthesis of the Marine Phosphomacrolide, (−)-Enigmazole A, Exploiting Multicomponent Type I Anion Relay Chemistry (ARC) in Conjunction with a Late-Stage Petasis–Ferrier Union/Rearrangement
Published in Journal of organic chemistry (01-06-2018)“…An effective late-stage large-fragment union/rearrangement exploiting the Petasis–Ferrier protocol, in conjunction with multicomponent Type I Anion Relay…”
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9
LC-MS guided isolation and dereplication of Lycopodium alkaloids from Lycopodium cernuum var. sikkimense of different geographical origins
Published in Phytochemistry (Oxford) (01-04-2019)“…Lycopodium alkaloids (LAs) are the characteristic metabolites of club mosses. Chemical differences often exist in different specimens of a single plant species…”
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Journal Article -
10
Zirconium/Nickel‐Mediated One‐Pot Ketone Synthesis
Published in Angewandte Chemie (28-08-2017)“…A zirconium/nickel‐mediated one‐pot synthesis of ketones is reported. In the presence of Zn or Mn, Cp2ZrCl2 was found to dramatically accelerate the coupling…”
Get full text
Journal Article -
11
Unified, Efficient, and Scalable Synthesis of Halichondrins: Zirconium/Nickel‐Mediated One‐Pot Ketone Synthesis as the Final Coupling Reaction
Published in Angewandte Chemie (28-08-2017)“…Unified, efficient, and scalable syntheses of the halichondrin natural products are reported. A newly developed Zr/Ni‐mediated one‐pot ketone synthesis was…”
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Journal Article -
12
Total synthesis of (–)-enigmazole A
Published 01-01-2015“…The dissertation contained herein presents a total synthesis of (–)-enigmazole A utilizing a late-stage large-fragment Petasis-Ferrier union/rearrangement…”
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Dissertation