Search Results - "Ai, Nana"

Rescue of bmp15 deficiency in zebrafish by mutation of inha reveals mechanisms of BMP15 regulation of folliculogenesis by Zhai, Yue, Zhang, Xin, Zhao, Cheng, Geng, Ruijing, Wu, Kun, Yuan, Mingzhe, Ai, Nana, Ge, Wei

“…As an oocyte-specific growth factor, bone morphogenetic protein 15 (BMP15) plays a critical role in controlling folliculogenesis. However, the mechanism of…”
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Loss of Growth Hormone Gene (gh1) in Zebrafish Arrests Folliculogenesis in Females and Delays Spermatogenesis in Males by Hu, Zhe, Ai, Nana, Chen, Weiting, Wong, Queenie Wing-Lei, Ge, Wei

“…As a master hormone controlling growth and metabolism, GH is also known to regulate reproduction. Studies in mammals have shown that mutations in GH or its…”
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Genetic analysis of activin/inhibin β subunits in zebrafish development and reproduction by Zhao, Cheng, Zhai, Yue, Geng, Ruijing, Wu, Kun, Song, Weiyi, Ai, Nana, Ge, Wei

“…Activin and inhibin are both dimeric proteins sharing the same β subunits that belong to the TGF-β superfamily. They are well known for stimulating and…”
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Aspirin reduces Ponatinib-induced cardiovascular toxic phenotypes and death in zebrafish by Yu, Ruiqi, Ai, Nana, Huang, Chen, Wang, Danni, Bian, Chao, Ge, Wei, Chong, Cheong-Meng

“…Ponatinib (Iclusig) is an oral tyrosine kinase BCR-ABL inhibitor for treating patients with Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+…”
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Design and Characterization of a Dual‐Interval Elastic Force Sensor for Robot‐Assisted Microinjection by Lyu, Zekui, Ai, Nana, Ge, Wei, Xu, Qingsong

“…Robot‐assisted microinjection has been widely implemented in the field of experimental biology research. Force perception is more accurate than visual feedback…”
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Pharmacological blockade of cholesterol trafficking by cepharanthine in endothelial cells suppresses angiogenesis and tumor growth by Lyu, Junfang, Yang, Eun Ju, Head, Sarah A., Ai, Nana, Zhang, Baoyuan, Wu, Changjie, Li, Ruo-Jing, Liu, Yifan, Yang, Chen, Dang, Yongjun, Kwon, Ho Jeong, Ge, Wei, Liu, Jun O., Shim, Joong Sup

“…Cholesterol is an important modulator of membrane protein function and signaling in endothelial cells, thus making it an emerging target for anti-angiogenic…”
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Design of an automated robotic microinjection system for batch injection of zebrafish embryos and larvae by Guo, Zhongyi, Ai, Nana, Ge, Wei, Xu, Qingsong

“…This paper presents the design of a vision-based automated robotic microinjection system for batch injection of both zebrafish embryos and larvae. A novel…”
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Crowded environments tune the fold-switching in metamorphic proteins by Zhang, Ning, Guan, Wenyan, Cui, Shouqi, Ai, Nana

“…Metamorphic proteins such as circadian clock protein KaiB and human chemokine XCL1 play vital roles in regulating biological processes, including gene…”
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Magnetic Mobile Microrobots for Upstream and Downstream Navigation in Biofluids with Variable Flow Rate by Wu, Zehao, Zhang, Yuting, Ai, Nana, Chen, Haoran, Ge, Wei, Xu, Qingsong

“…Magnetic mobile microrobots navigating biofluids with both upstream and downstream locomotion provide a promising solution to targeted drug delivery for…”
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Nicotinamide promotes cardiomyocyte derivation and survival through kinase inhibition in human pluripotent stem cells by Meng, Ya, Song, Chengcheng, Ren, Zhili, Li, Xiaohong, Yang, Xiangyu, Ai, Nana, Yang, Yang, Wang, Dongjin, Zhan, Meixiao, Wang, Jiaxian, LEI, Chon Lok, Liu, Weiwei, Ge, Wei, Lu, Ligong, Chen, Guokai

“…Nicotinamide, the amide form of Vitamin B3, is a common nutrient supplement that plays important role in human fetal development. Nicotinamide has been widely…”
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ROCK in CNS: Different Roles of Isoforms and Therapeutic Target for Neurodegenerative Disorders by Chong, Cheong-Meng, Ai, Nana, Lee, Simon Ming-Yuen

“…Rho-associated protein kinase (ROCK) is a serine-threonine kinase originally identified as a crucial regulator of actin cytoskeleton. Recent studies have…”
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Exogenous iron impairs the anti-cancer effect of ascorbic acid both in vitro and in vivo by Zhong, Bingling, Zhao, Lin, Yu, Jie, Hou, Ying, Ai, Nana, Lu, Jin-Jian, Ge, Wei, Chen, Xiuping

“…[Display omitted] •Ascorbic acid triggered ROS/Ca2+ dependent necrosis.•Extracellular Fe2+/Fe3+ abrogated the cytotoxicity of ascorbic acid in vitro.•Fe2+/Fe3+…”
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Endogenous IGF Signaling Directs Heterogeneous Mesoderm Differentiation in Human Embryonic Stem Cells by Yang, Yang, Ren, Zhili, Xu, Faxiang, Meng, Ya, Zhang, Yumeng, Ai, Nana, Long, Yan, Fok, Hio Ian, Deng, Chunhao, Zhao, Xianyang, Huang, Liancheng, Zhao, Qi, Wang, Jiaxian, Liu, Weiwei, Ge, Wei, Chen, Guokai

“…During embryogenesis, various cell types emerge simultaneously from their common progenitors under the influence of intrinsic signals. Human embryonic stem…”
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Genetic evidence for differential functions of figla and nobox in zebrafish ovarian differentiation and folliculogenesis by Wu, Kun, Zhai, Yue, Qin, Mingming, Zhao, Cheng, Ai, Nana, He, Jianguo, Ge, Wei

“…FIGLA and NOBOX are important oocyte-specific transcription factors. Both figla-/- and nobox-/- mutants showed all-male phenotype in zebrafish due to increased…”
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Ponatinib exerts anti-angiogenic effects in the zebrafish and human umbilical vein endothelial cells via blocking VEGFR signaling pathway by Ai, Nana, Chong, Cheong-Meng, Chen, Weiting, Hu, Zhe, Su, Huanxing, Chen, Guokai, Lei Wong, Queenie Wing, Ge, Wei

“…Angiogenesis is a hallmark for cancer development because it is essential for cancer growth and provides the route for cancer cell migration (metastasis)…”
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Publisher Correction: Genetic evidence for differential functions of figla and nobox in zebrafish ovarian differentiation and folliculogenesis by Wu, Kun, Zhai, Yue, Qin, Mingming, Zhao, Cheng, Ai, Nana, He, Jianguo, Ge, Wei

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Corrigendum: An in vivo fluorescence resonance energy transfer-based imaging platform for targeted drug discovery and cancer therapy by Xing, Fuqiang, Ai, Nana, Huang, Shigao, Jiang, Cheng, Mughal, Muhammad Jameel, Ge, Wei, Wang, Guanyu, Deng, Chu-Xia

“…[This corrects the article DOI: 10.3389/fbioe.2022.839078.]…”
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An In Vivo Fluorescence Resonance Energy Transfer-Based Imaging Platform for Targeted Drug Discovery and Cancer Therapy by Xing, Fuqiang, Ai, Nana, Huang, Shigao, Jiang, Cheng, Mughal, Muhammad Jameel, Ge, Wei, Wang, Guanyu, Deng, Chu-Xia

“…In the present study, an efficient drug screening platform is established based on FRET technique. We transfected cancer cells with FRET-based caspase-3 (C3)…”
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A novel bioengineered fragment peptide of Vasostatin-1 exerts smooth muscle pharmacological activities and anti-angiogenic effects via blocking VEGFR signalling pathway by Wei, Ran, Wu, Qiushuang, Ai, Nana, Wang, Lei, Zhou, Mei, Shaw, Chris, Chen, Tianbao, Ye, Richard Dequan, Ge, Wei, Siu, Shirley W.I., Kwok, Hang Fai

“…[Display omitted] Chromogranin A (CgA) is a hydrophilic glycoprotein released by post-ganglionic sympathetic neurons. CgA consists of a single peptide chain…”
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Design of a High-Throughput Robotic Batch Microinjection System for Zebrafish Larvae-Based on Image Potential Energy by Chi, Ziqiang, Xu, Qingsong, Ai, Nana, Ge, Wei

“…Microinjection of zebrafish larvae is widely used in vaccine development, drug screening, gene research, etc. Conventional manual injection has the…”
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