Search Results - "Ai, Jianzhong"

Editorial: Biomarkers and immunotherapy for genitourinary tumors by Han, Zeyu, Ai, Jianzhong

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Broaden Horizons: The Advancement of Interstitial Cystitis/Bladder Pain Syndrome by Li, Jin, Yi, Xianyanling, Ai, Jianzhong

“…Interstitial cystitis/bladder pain syndrome (IC/BPS) is a debilitating disease that induces mental stress, lower urinary symptoms, and pelvic pain, therefore…”
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Tumor-antigens and immune landscapes identification for prostate adenocarcinoma mRNA vaccine by Zheng, Xiaonan, Xu, Hang, Yi, Xianyanling, Zhang, Tianyi, Wei, Qiang, Li, Hong, Ai, Jianzhong

“…Prostate adenocarcinoma (PRAD) is a leading cause of death among men. Messenger ribonucleic acid (mRNA) vaccine presents an attractive approach to achieve…”
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Tumor antigens and immune subtypes guided mRNA vaccine development for kidney renal clear cell carcinoma by Xu, Hang, Zheng, Xiaonan, Zhang, Shiyu, Yi, Xianyanling, Zhang, Tianyi, Wei, Qiang, Li, Hong, Ai, Jianzhong

“…Current treatment strategy for kidney renal clear cell carcinoma (KIRC) is limited. Tumor-associated antigens, especially neoantigen-based personalized mRNA…”
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Cellular mechanotransduction in health and diseases: from molecular mechanism to therapeutic targets by Di, Xingpeng, Gao, Xiaoshuai, Peng, Liao, Ai, Jianzhong, Jin, Xi, Qi, Shiqian, Li, Hong, Wang, Kunjie, Luo, Deyi

“…Cellular mechanotransduction, a critical regulator of numerous biological processes, is the conversion from mechanical signals to biochemical signals regarding…”
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Association of BRCA mutation status with the efficacy of poly (ADP-ribose) polymerase inhibitors in cancer: A systematic review and meta-analysis by Wang, Sheng, Xu, Hang, Ai, Jianzhong, Yang, Lu

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Tumor‐associated macrophages promote bladder tumor growth through PI3K/AKT signal induced by collagen by Qiu, Shi, Deng, Linghui, Liao, Xinyang, Nie, Ling, Qi, Fang, Jin, Kun, Tu, Xiang, Zheng, Xiaonan, Li, Jiakun, Liu, Liangren, Liu, Zhenhua, Bao, Yige, Ai, Jianzhong, Lin, Tianhai, Yang, Lu, Wei, Qiang

“…The tumor microenvironment is associated with various tumor progressions, including cancer metastasis, immunosuppression, and tumor sustained growth…”
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Identification of a Novel Nomogram to Predict Progression Based on the Circadian Clock and Insights Into the Tumor Immune Microenvironment in Prostate Cancer by Feng, Dechao, Xiong, Qiao, Zhang, Facai, Shi, Xu, Xu, Hang, Wei, Wuran, Ai, Jianzhong, Yang, Lu

“…Currently, the impact of the circadian rhythm on the tumorigenesis and progression of prostate cancer (PCA) has yet to be understood. In this study, we first…”
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DOK3 promotes proliferation and inhibits apoptosis of prostate cancer via the NF-κB signaling pathway by Jin, Kun, Qiu, Shi, Chen, Bo, Zhang, Zilong, Zhang, Chichen, Zhou, Xianghong, Yang, Lu, Ai, Jianzhong, Wei, Qiang

“…DOK3 (Downstream of kinase 3) is involved primarily with immune cell infiltration. Recent research reported the role of DOK3 in tumor progression, with…”
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Associations between the dietary inflammatory index and urinary incontinence among women younger than 65 years by Zhang, Shiyu, Bian, Haiyang, Qiu, Shi, Cai, Boyu, Jin, Kun, Zheng, Xiaonan, Li, Jiakun, Tu, Xiang, Ai, Jianzhong, Yang, Lu, Wei, Qiang

“…The purpose of this study was to evaluate the association between dietary inflammatory index (DII) and urinary incontinence (UI) among a representative sample…”
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CXCL8 in Tumor Biology and Its Implications for Clinical Translation by Xiong, Xingyu, Liao, Xinyang, Qiu, Shi, Xu, Hang, Zhang, Shiyu, Wang, Sheng, Ai, Jianzhong, Yang, Lu

“…The chemokine CXCL8 has been found to play an important role in tumor progression in recent years. CXCL8 activates multiple intracellular signaling pathways by…”
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Alteration of Gut Microbiota Relates to Metabolic Disorders in Primary Aldosteronism Patients by Liu, Yu, Jiang, Qingyao, Liu, Zhihong, Shen, Sikui, Ai, Jianzhong, Zhu, Yuchun, Zhou, Liang

“…This study aimed to determine the relationships among gut microbiota, primary aldosteronism (PA), and related metabolic disorders. The study enrolled 13 PA…”
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Short DNA Hairpins Compromise Recombinant Adeno-Associated Virus Genome Homogeneity by Xie, Jun, Mao, Qin, Tai, Phillip W.L., He, Ran, Ai, Jianzhong, Su, Qin, Zhu, Ye, Ma, Hong, Li, Jia, Gong, Shoufang, Wang, Dan, Gao, Zhen, Li, Mengxin, Zhong, Li, Zhou, Heather, Gao, Guangping

“…Short hairpin (sh)RNAs delivered by recombinant adeno-associated viruses (rAAVs) are valuable tools to study gene function in vivo and a promising gene therapy…”
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The role of interleukin-6/interleukin-6 receptor signaling in the mechanical stress-induced extracellular matrix remodeling of bladder smooth muscle by He, Qing, Lin, Yifei, Liao, Banghua, Zhou, Liang, Ai, Jianzhong, Jin, Xi, Li, Hong, Wang, Kunjie

“…Extracellular matrix (ECM) remodeling is strongly associated with pathological changes induced by bladder outlet obstruction (BOO). In this study, we…”
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Crosstalk between Tumor-Associated Macrophages and MicroRNAs: A Key Role in Tumor Microenvironment by Zhou, Xianghong, Chen, Bo, Zhang, Zilong, Huang, Yin, Li, Jinze, Wei, Qiang, Cao, Dehong, Ai, Jianzhong

“…As an in-depth understanding of immunotherapy continues to grow, current anticancer therapy research is increasingly focused on the tumor microenvironment…”
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mTORC1-Dependent Protein and Parkinson's Disease: A Mendelian Randomization Study by Tan, Cheng, Ai, Jianzhong, Zhu, Ye

“…The mTOR pathway is crucial in controlling the growth, differentiation, and survival of neurons, and its pharmacological targeting has promising potential as a…”
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Construction of PANoptosis signature: Novel target discovery for prostate cancer immunotherapy by Yi, Xianyanling, Li, Jin, Zheng, Xiaonan, Xu, Hang, Liao, Dazhou, Zhang, Tianyi, Wei, Qiang, Li, Hong, Peng, Jiajie, Ai, Jianzhong

“…PANoptosis pathway gene sets encompassing pyroptosis, apoptosis, and necroptosis were identified from the MSigDB database. We analyzed the perturbations and…”
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IGFBP7 and the Tumor Immune Landscape: A Novel Target for Immunotherapy in Bladder Cancer by Yi, Xianyanling, Zheng, Xiaonan, Xu, Hang, Li, Jin, Zhang, Tianyi, Ge, Peng, Liao, Dazhou, Li, Hong, Lyu, Xiaoyan, Ai, Jianzhong

“…Insulin-like growth factor binding protein-7 (IGFBP7) was recently reported to be a ligand of CD93, a potential target to normalize vasculature and attenuate…”
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Cell softness reveals tumorigenic potential via ITGB8/AKT/glycolysis signaling in a mice model of orthotopic bladder cancer by Qiu, Shi, Qiu, Yaqi, Deng, Linghui, Nie, Ling, Ge, Liming, Zheng, Xiaonan, Jin, Di, Jin, Kun, Zhou, Xianghong, Su, Xingyang, Cai, Boyu, Li, Jiakun, Tu, Xiang, Gong, Lina, Liu, Liangren, Liu, Zhenhua, Bao, Yige, Ai, Jianzhong, Lin, Tianhai, Yang, Lu, Wei, Qiang

“…Bladder cancer, characterized by a high potential of tumor recurrence, has high lifelong monitoring and treatment costs. To date, tumor cells with intrinsic…”
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rAAV-delivered PTEN therapeutics for prostate cancer by Ai, Jianzhong, Li, Jia, Su, Qin, Ma, Hong, Wei, Qiang, Li, Hong, Gao, Guangping

“…Effective treatments for prostate cancer (PCa) require further development, and previous studies have reported that PTEN and its downstream target CDKN1B are…”
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