Search Results - "Ai, Daiqiao"

DEEPCYPs: A deep learning platform for enhanced cytochrome P450 activity prediction by Ai, Daiqiao, Cai, Hanxuan, Wei, Jiajia, Zhao, Duancheng, Chen, Yihao, Wang, Ling

“…Cytochrome P450 (CYP) is a superfamily of heme-containing oxidizing enzymes involved in the metabolism of a wide range of medicines, xenobiotics, and…”
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A multi-task FP-GNN framework enables accurate prediction of selective PARP inhibitors by Ai, Daiqiao, Wu, Jingxing, Cai, Hanxuan, Zhao, Duancheng, Chen, Yihao, Wei, Jiajia, Xu, Jianrong, Zhang, Jiquan, Wang, Ling

“…PARP (poly ADP-ribose polymerase) family is a crucial DNA repair enzyme that responds to DNA damage, regulates apoptosis, and maintains genome stability;…”
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Targeting the PI3K/AKT/mTOR Signaling Pathway in the Treatment of Human Diseases: Current Status, Trends, and Solutions by Huang, Jindi, Chen, Liye, Wu, Jiangxia, Ai, Daiqiao, Zhang, Ji-Quan, Chen, Tie-Gen, Wang, Ling

“…The phosphoinositide 3-kinase (PI3K)/​protein kinase B (AKT)/​mammalian target of rapamycin (mTOR) pathway is one of the most important intracellular pathways…”
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Design, synthesis and biological evaluation of novel hybrids targeting mTOR and HDACs for potential treatment of hepatocellular carcinoma by Zhai, Shiyang, Zhang, Huimin, Chen, Rui, Wu, Jiangxia, Ai, Daiqiao, Tao, Shunming, Cai, Yike, Zhang, Ji-Quan, Wang, Ling

“…Hepatocellular carcinoma (HCC) is a major contributor to global cancer incidence and mortality. Many pathways are involved in the development of HCC and…”
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