Search Results - "Ahuja, Akshay"
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Pathogen-Induced TLR4-TRIF Innate Immune Signaling in Hematopoietic Stem Cells Promotes Proliferation but Reduces Competitive Fitness
Published in Cell stem cell (03-08-2017)“…Bacterial infection leads to consumption of short-lived innate immune effector cells, which then need to be replenished from hematopoietic stem and progenitor…”
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A short G1 phase imposes constitutive replication stress and fork remodelling in mouse embryonic stem cells
Published in Nature communications (15-02-2016)“…Embryonic stem cells (ESCs) represent a transient biological state, where pluripotency is coupled with fast proliferation. ESCs display a constitutively active…”
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A Dual Role of Caspase-8 in Triggering and Sensing Proliferation-Associated DNA Damage, a Key Determinant of Liver Cancer Development
Published in Cancer cell (11-09-2017)“…Concomitant hepatocyte apoptosis and regeneration is a hallmark of chronic liver diseases (CLDs) predisposing to hepatocellular carcinoma (HCC). Here, we…”
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Journal Article Web Resource -
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Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing
Published in Nature cell biology (01-07-2016)“…The cyclin-dependent kinase inhibitor p21 WAF1/CIP1 (p21) is a cell-cycle checkpoint effector and inducer of senescence, regulated by p53. Yet, evidence…”
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Pathogen-Induced TLR4-TRIF Innate Immune Signaling in Hematopoietic Stem Cells Promotes Proliferation but Reduces Competitive Fitness
Published in Cell stem cell (02-07-2020)Get full text
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Social capital and peer influence of tobacco consumption: a cross-sectional study among household heads in rural Uttar Pradesh, India
Published in BMJ open (30-06-2020)“…ObjectiveHaving the world’s second-largest tobacco-consuming population, tobacco control is a priority agenda of the Indian Government. Yet, there is no…”
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Pyrimidine Pool Disequilibrium Induced by a Cytidine Deaminase Deficiency Inhibits PARP-1 Activity, Leading to the Under Replication of DNA
Published in PLoS genetics (01-07-2015)“…Genome stability is jeopardized by imbalances of the dNTP pool; such imbalances affect the rate of fork progression. For example, cytidine deaminase (CDA)…”
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Journal Article -
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Does social capital increase healthcare financing's projection? Results from the rural household of Uttar Pradesh, India
Published in SSM - population health (01-09-2021)“…In the absence of adequate social security, out-of-pocket health expenditure compels households to adopt coping strategies, such as utilizing savings, selling…”
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Social capital and utilization of immunization service: A multilevel analysis in rural Uttar Pradesh, India
Published in SSM - population health (01-04-2020)“…The National Health Policy (2017) of India advocates Universal Health Coverage through inclusive growth, decentralization, and rebuilding a cohesive community…”
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The Dynamic Nature of Human Dermal Fibroblasts Is Defined by Marked Variation in the Gene Expression of Specific Cytoskeletal Markers
Published in Life (Basel, Switzerland) (22-06-2022)“…The evidence for fibroblast heterogeneity is continuously increasing, and recent work has shed some light on the existence of different sub-populations of…”
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Human Basal and Suprabasal Keratinocytes Are Both Able to Generate and Maintain Dermo-Epidermal Skin Substitutes in Long-Term In Vivo Experiments
Published in Cells (Basel, Switzerland) (09-07-2022)“…The basal layer of human interfollicular epidermis has been described to harbour both quiescent keratinocyte stem cells and a transit amplifying cell…”
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Determinants of cardiovascular diseases among Indian expatriates residing in Ajman, UAE-A Pilot study
Published in Population medicine (27-04-2023)Get full text
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Bridging the gap or widening the divide? Exploring the dual role of social capital in healthcare financing in rural Uttar Pradesh, India
Published in Social science & medicine (1982) (01-06-2024)“…Social capital, defined as the nature of the social relationship and the resources embedded within the social network of an individual or community, influences…”
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The effects of Atm haploinsufficiency on mutation rate in the mouse germ line and somatic tissue
Published in Mutagenesis (01-09-2008)“…Using single-molecule polymerase chain reaction, the frequency of spontaneous and radiation-induced mutation at an expanded simple tandem repeat (ESTR) locus…”
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Poly(ADP-Ribosyl) Glycohydrolase Prevents the Accumulation of Unusual Replication Structures during Unperturbed S Phase
Published in Molecular and cellular biology (01-03-2015)“…Poly(ADP-ribosyl)ation (PAR) has been implicated in various aspects of the cellular response to DNA damage and genome stability. Although 17 human…”
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Pyrimidine Pool Disequilibrium Induced by a Cytidine Deaminase Deficiency Inhibits PARP-1 Activity, Leading to the Under Replication of DNA: e1005384
Published in PLoS genetics (01-07-2015)“…Genome stability is jeopardized by imbalances of the dNTP pool; such imbalances affect the rate of fork progression. For example, cytidine deaminase (CDA)…”
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Journal Article -
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Battery Electric Vehicle Global Adoption Practices and Distribution Grid Impacts: A Preliminary Case Study for Delhi, India
Published in Technology and economics of smart grids and sustainable energy (01-12-2017)“…Electric vehicles (EV) represent a large market opportunity to address macro- and micro-level carbon emissions, electric grid integration, and technological…”
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Electric transportation action plan for India
Published in 2016 First International Conference on Sustainable Green Buildings and Communities (SGBC) (01-12-2016)“…After almost 70-years after independence in 1947, India stands at the deterministic crossroads of economic growth and energy needs for over a billion people,…”
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Conference Proceeding -
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Battery Electric Vehicle Global Adoption Practices and Distribution Grid Impacts
Published in Technology and economics of smart grids and sustainable energy (01-01-2017)“…Electric vehicles (EV) represent a large market opportunity to address macro- and micro-level carbon emissions, electric grid integration, and technological…”
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The Other Side of the Mirror: An American Travels Through Syria
Published in Ploughshares (01-10-2011)“…The Other Side of the Mirror: An American Travels Through Syria by Brooke Allen is reviewed…”
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