Search Results - "Ahsan, Md. Kaimul"
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Cardioprotection by resveratrol: a novel mechanism via autophagy involving the mTORC2 pathway
Published in Cardiovascular research (01-04-2010)“…Aims On the basis of our previous reports that cardioprotection induced by ischaemic preconditioning induces autophagy and that resveratrol, a polyphenolic…”
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Redox regulation of cell survival by the thioredoxin superfamily: an implication of redox gene therapy in the heart
Published in Antioxidants & redox signaling (01-11-2009)“…Reactive oxygen species (ROS) are the key mediators of pathogenesis in cardiovascular diseases. Members of the thioredoxin superfamily take an active part in…”
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Linaclotide activates guanylate cyclase‐C/cGMP/protein kinase‐II‐dependent trafficking of CFTR in the intestine
Published in Physiological reports (01-06-2017)“…The transmembrane receptor guanylyl cyclase‐C (GC‐C), expressed on enterocytes along the intestine, is the molecular target of the GC‐C agonist peptide…”
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Thioredoxin-binding protein-2 deficiency enhances methionine-choline deficient diet-induced hepatic steatosis but inhibits steatohepatitis in mice
Published in Antioxidants & redox signaling (01-10-2009)“…In nonalcoholic fatty liver disease, oxidative stress is believed to play a crucial role as a second-hit for the progression of simple steatosis to…”
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Thioredoxin binding protein-2 mediates metabolic adaptation in response to lipopolysaccharide in vivo
Published in Critical care medicine (01-12-2010)Get full text
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Activation of adenosine receptor A2A increases HSC proliferation and inhibits death and senescence by down-regulation of p53 and Rb
Published in Frontiers in pharmacology (2014)“…During fibrosis hepatic stellate cells (HSC) undergo activation, proliferation, and senescence but the regulation of these important processes is poorly…”
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Co‐ordinated autophagy with resveratrol and γ‐tocotrienol confers synergetic cardioprotection
Published in Journal of cellular and molecular medicine (01-10-2010)“…This study compared two dietary phytochemicals, grape‐derived resveratrol and palm oil‐derived γ‐tocotrienol, either alone or in combination, on the…”
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Thioredoxin and thioredoxin binding protein 2 in the liver
Published in IUBMB life (01-10-2008)“…Thioredoxin (TRX) is a 12‐kDa protein with redox‐active dithiol in the active site ‐Cys‐Gly‐Pro‐Cys‐ and constitutes a major thiol reducing system. TRX…”
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Thioredoxin binding protein-2 mediates metabolic adaptation in response to lipopolysaccharide in vivo
Published in Critical care medicine (01-12-2010)“…OBJECTIVES:Endotoxin triggers a reorganization of the energy metabolic pathway, including the promotion of fatty acid utilization to adapt to a high energy…”
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Downregulation of cardiac lineage protein-1 confers cardioprotection through the upregulation of redox effectors
Published in FEBS letters (04-01-2010)“…CLP-1, the mouse homologue of human Hexim1 protein, exerts inhibitory control on transcriptional elongation factor-b of RNA transcript elongation. Previously,…”
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Thioredoxin-binding protein-2 (TBP-2): Its potential roles in the aging process
Published in BioFactors (Oxford) (2006)“…Thioredoxin (TRX) binding protein‐2 (TBP‐2), a negative regulator of TRX, is involved in intracellular redox regulation and cellular growth. The expression of…”
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Serum and Glucocorticoid‐Inducible Kinase 1 (SGK1): An Important Contributor to Diarrhea and Malabsorption in Microvillus Inclusion Disease (MVID)
Published in The FASEB journal (01-05-2022)“…Microvillus Inclusion Disease (MVID) is a lethal congenital diarrheal disease resulting from loss of function mutations in the actin motor myosin VB (MYO5B)…”
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Glucocorticoids and serum- and glucocorticoid-inducible kinase 1 are potent regulators of CFTR in the native intestine: implications for stress-induced diarrhea
Published in American journal of physiology: Gastrointestinal and liver physiology (01-08-2020)“…Nongenomic glucocorticoid (GC) and serum- and glucocorticoid-inducible kinase 1 (SGK1) signaling regulate ion transport, but CFTR has not been investigated in…”
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Mechanism of Linaclotide‐induced Trafficking of CFTR and NHE3 in the Human Intestinal Cell‐lines Caco‐2 BBe and T84 cells
Published in The FASEB journal (01-04-2015)“…Abstract only Linaclotide (Linzess) is a potent guanylate cyclase‐C (GCC) agonist in clinical use for treatment of chronic constipation and irritable bowel…”
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Modulation of microRNA 20b with resveratrol and longevinex is linked with their potent anti‐angiogenic action in the ischaemic myocardium and synergestic effects of resveratrol and γ‐tocotrienol
Published in Journal of cellular and molecular medicine (01-10-2012)“…Resveratrol, a constituent of red wine, and γ‐tocotrienol, a constituent of palm oil are important for cardioprotection. Although microRNAs are known…”
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Identification of intestinal ion transport defects in microvillus inclusion disease
Published in American journal of physiology: Gastrointestinal and liver physiology (01-07-2016)“…Loss of function mutations in the actin motor myosin Vb (Myo5b) lead to microvillus inclusion disease (MVID) and death in newborns and children. MVID results…”
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Loss of Serum Glucocorticoid-Inducible Kinase 1 SGK1 Worsens Malabsorption and Diarrhea in Microvillus Inclusion Disease (MVID)
Published in Journal of clinical medicine (19-07-2022)“…Microvillus inclusion disease (MVID), a lethal congenital diarrheal disease, results from loss of function mutations in the apical actin motor myosin VB…”
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Loss of thioredoxin-binding protein-2/vitamin D3 up-regulated protein 1 in human T-cell leukemia virus type I-dependent T-cell transformation: Implications for adult T-cell leukemia leukemogenesis
Published in Cancer research (Chicago, Ill.) (15-02-2004)“…Human T-cell leukemia virus type I (HTLV-I) is the causative agent of adult T-cell leukemia (ATL). However, the low incidence of ATL among HTLV-I-infected…”
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Co-ordinated autophagy with resveratrol and [gamma]-tocotrienol confers synergetic cardioprotection
Published in Journal of cellular and molecular medicine (01-10-2010)“…This study compared two dietary phytochemicals, grape-derived resveratrol and palm oil-derived ...-tocotrienol, either alone or in combination, on the…”
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