Search Results - "Ahrens, Christian"
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Protter: interactive protein feature visualization and integration with experimental proteomic data
Published in Bioinformatics (15-03-2014)“…The ability to integrate and visualize experimental proteomic evidence in the context of rich protein feature annotations represents an unmet need of the…”
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Mercury (II) reduction and co-precipitation of metallic mercury on hydrous ferric oxide in contaminated groundwater
Published in The Science of the total environment (01-01-2016)“…Mercury (Hg) speciation and sorption analyses in contaminated aquifers are useful for understanding transformation, retention, and mobility of Hg in…”
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Explosive cell lysis as a mechanism for the biogenesis of bacterial membrane vesicles and biofilms
Published in Nature communications (14-04-2016)“…Many bacteria produce extracellular and surface-associated components such as membrane vesicles (MVs), extracellular DNA and moonlighting cytosolic proteins…”
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Towards the characterization of the hidden world of small proteins in Staphylococcus aureus, a proteogenomics approach
Published in PLoS genetics (01-06-2021)“…Small proteins play essential roles in bacterial physiology and virulence, however, automated algorithms for genome annotation are often not yet able to…”
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A Practical Guide to Small Protein Discovery and Characterization Using Mass Spectrometry
Published in Journal of bacteriology (18-01-2022)“…Small proteins of up to ∼50 amino acids are an abundant class of biomolecules across all domains of life. Yet due to the challenges inherent in their size,…”
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Long-read based de novo assembly of low-complexity metagenome samples results in finished genomes and reveals insights into strain diversity and an active phage system
Published in BMC microbiology (25-06-2019)“…Complete and contiguous genome assemblies greatly improve the quality of subsequent systems-wide functional profiling studies and the ability to gain novel…”
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Pushing the limits of de novo genome assembly for complex prokaryotic genomes harboring very long, near identical repeats
Published in Nucleic acids research (28-09-2018)“…Abstract Generating a complete, de novo genome assembly for prokaryotes is often considered a solved problem. However, we here show that Pseudomonas koreensis…”
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Generating and navigating proteome maps using mass spectrometry
Published in Nature reviews. Molecular cell biology (01-11-2010)“…Key Points Complete proteome reference maps, which contain validated, mass spectrometry (MS)-derived, reference fragment ion spectra for unique peptides for…”
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Competition assays and physiological experiments of soil and phyllosphere yeasts identify Candida subhashii as a novel antagonist of filamentous fungi
Published in BMC microbiology (05-01-2017)“…While recent advances in next generation sequencing technologies have enabled researchers to readily identify countless microbial species in soil, rhizosphere,…”
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Volatile Organic Compounds from Native Potato-associated Pseudomonas as Potential Anti-oomycete Agents
Published in Frontiers in microbiology (23-11-2015)“…The plant kingdom represents a prominent biodiversity island for microbes that associate with the below- or aboveground organs of vegetal species. Both the…”
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A Peptidomimetic Antibiotic Targets Outer Membrane Proteins and Disrupts Selectively the Outer Membrane in Escherichia coli
Published in The Journal of biological chemistry (22-01-2016)“…Increasing antibacterial resistance presents a major challenge in antibiotic discovery. One attractive target in Gram-negative bacteria is the unique…”
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PeptideClassifier for protein inference and targeted quantitative proteomics
Published in Nature biotechnology (01-07-2010)Get full text
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Identification and functional characterization of N-terminally acetylated proteins in Drosophila melanogaster
Published in PLoS biology (03-11-2009)“…Protein modifications play a major role for most biological processes in living organisms. Amino-terminal acetylation of proteins is a common modification…”
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Seasonal Dynamics of Glyphosate and AMPA in Lake Greifensee: Rapid Microbial Degradation in the Epilimnion During Summer
Published in Environmental science & technology (17-04-2018)“…Occurrence and fate of glyphosate, a widely used herbicide, and its main metabolite AMPA was investigated in Lake Greifensee, Switzerland. Monthly vertical…”
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Detection of Known and Novel Small Proteins in Pseudomonas stutzeri Using a Combination of Bottom-Up and Digest-Free Proteomics and Proteogenomics
Published in Analytical chemistry (Washington) (15-08-2023)“…Small proteins of around 50 aa in length have been largely overlooked in genetic and biochemical assays due to the inherent challenges with detecting and…”
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An integrative strategy to identify the entire protein coding potential of prokaryotic genomes by proteogenomics
Published in Genome research (01-12-2017)“…Accurate annotation of all protein-coding sequences (CDSs) is an essential prerequisite to fully exploit the rapidly growing repertoire of completely sequenced…”
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Comparative functional analysis of the Caenorhabditis elegans and Drosophila melanogaster proteomes
Published in PLoS biology (01-03-2009)“…The nematode Caenorhabditis elegans is a popular model system in genetics, not least because a majority of human disease genes are conserved in C. elegans. To…”
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The AHL- and BDSF-dependent quorum sensing systems control specific and overlapping sets of genes in Burkholderia cenocepacia H111
Published in PloS one (20-11-2012)“…Quorum sensing in Burkholderia cenocepacia H111 involves two signalling systems that depend on different signal molecules, namely N-acyl homoserine lactones…”
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Cis-2-dodecenoic acid receptor RpfR links quorum-sensing signal perception with regulation of virulence through cyclic dimeric guanosine monophosphate turnover
Published in Proceedings of the National Academy of Sciences - PNAS (18-09-2012)“…Many bacterial pathogens produce diffusible signal factor (DSF)-type quorum sensing (QS) signals in modulation of virulence and biofilm formation. Previous…”
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Bacterial tolerance to host-exuded specialized metabolites structures the maize root microbiome
Published in Proceedings of the National Academy of Sciences - PNAS (31-10-2023)“…Plants exude specialized metabolites from their roots, and these compounds are known to structure the root microbiome. However, the underlying mechanisms are…”
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