Search Results - "Ahrens, Allison M"
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Flexible simultaneous mesoscale two-photon imaging of neural activity at high speeds
Published in Nature communications (17-11-2021)“…Understanding brain function requires monitoring local and global brain dynamics. Two-photon imaging of the brain across mesoscopic scales has presented…”
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jYCaMP: an optimized calcium indicator for two-photon imaging at fiber laser wavelengths
Published in Nature methods (01-07-2020)“…Femtosecond lasers at fixed wavelengths above 1,000 nm are powerful, stable and inexpensive, making them promising sources for two-photon microscopy…”
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Neural Activity in the Ventral Pallidum Encodes Variation in the Incentive Value of a Reward Cue
Published in The Journal of neuroscience (27-07-2016)“…There is considerable individual variation in the extent to which reward cues are attributed with incentive salience. For example, a food-predictive…”
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Running speed and REM sleep control two distinct modes of rapid interhemispheric communication
Published in Cell reports (Cambridge) (05-07-2022)“…Rhythmic gamma-band communication within and across cortical hemispheres is critical for optimal perception, navigation, and memory. Here, using multisite…”
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Reduction of Dopamine Synaptic Activity: Degradation of 50-kHz Ultrasonic Vocalization in Rats
Published in Behavioral neuroscience (01-04-2009)“…Vocal deficits are prevalent and debilitating in Parkinson's disease. These deficits may be related to the initial pathology of the nigrostriatal dopamine…”
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High-speed low-light in vivo two-photon voltage imaging of large neuronal populations
Published in Nature methods (01-07-2023)“…Monitoring spiking activity across large neuronal populations at behaviorally relevant timescales is critical for understanding neural circuit function. Unlike…”
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Neural circuits linking sleep and addiction: Animal models to understand why select individuals are more vulnerable to substance use disorders after sleep deprivation
Published in Neuroscience and biobehavioral reviews (01-01-2020)“…•There is individual variation in the effects of sleep loss on reward circuitry.•This individual variation has been difficult to study in preclinical animal…”
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Assessing the role of dopamine in limb and cranial-oromotor control in a rat model of Parkinson's disease
Published in Journal of communication disorders (01-09-2011)“…Abstract Parkinson's disease (PD) is a neurodegenerative disorder primarily characterized by sensorimotor dysfunction. The neuropathology of PD includes a loss…”
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Neurons of the Ventral Tegmental Area Encode Individual Differences in Motivational "Wanting" for Reward Cues
Published in The Journal of neuroscience (11-11-2020)“…It has been argued that the dopaminergic system is involved in the attribution of motivational value to reward predictive cues as well as prediction error. To…”
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Rats that sign-track are resistant to Pavlovian but not instrumental extinction
Published in Behavioural brain research (01-01-2016)“…•Sign trackers (STs) attribute more incentive salience to cues than goal trackers (GTs).•We examined STs and GTs when a Pavlovian cue was no longer…”
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Repeated intravenous cocaine experience: Development and escalation of pre-drug anticipatory 50-kHz ultrasonic vocalizations in rats
Published in Behavioural brain research (01-09-2010)“…Ultrasonic vocalization (USV) in the 50-kHz range occurs in rats immediately upon first-time exposure to cocaine or amphetamine, and rapidly increases with…”
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Individual differences in the conditioned and unconditioned rat 50-kHz ultrasonic vocalizations elicited by repeated amphetamine exposure
Published in Psychopharmacology (01-10-2013)“…Rationale Adult rats often produce 50-kHz ultrasonic vocalizations (USVs), particularly the frequency-modulated varieties, in appetitive situations. These…”
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The missing variable: ultrasonic vocalizations reveal hidden sensitization and tolerance-like effects during long-term cocaine administration
Published in Psychopharmacologia (01-02-2012)“…Rationale Subtypes of 50-kHz ultrasonic vocalizations (USVs) in rats are thought to reflect positive affect and occur with cocaine or amphetamine delivery. In…”
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DeepVID v2: self-supervised denoising with decoupled spatiotemporal enhancement for low-photon voltage imaging
Published in Neurophotonics (Print) (01-10-2024)“…Voltage imaging is a powerful tool for studying the dynamics of neuronal activities in the brain. However, voltage imaging data are fundamentally corrupted by…”
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Repeated intravenous amphetamine exposure: Rapid and persistent sensitization of 50-kHz ultrasonic trill calls in rats
Published in Behavioural brain research (30-01-2009)“…Short 50-kilohertz (kHz) range frequency-modulated ultrasonic vocalizations (USVs) produced by rats and mice are unconditionally elicited by drugs of abuse or…”
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Cocaine deprivation effect: Cue abstinence over weekends boosts anticipatory 50-kHz ultrasonic vocalizations in rats
Published in Behavioural brain research (06-12-2010)“…In drug dependence studies, rats are often tested daily with short breaks (such as weekends) spent untested in their home cages. Research on alcohol models has…”
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Dynamic Encoding of Incentive Salience in the Ventral Pallidum: Dependence on the Form of the Reward Cue
Published in eNeuro (01-03-2018)“…Some rats are especially prone to attribute incentive salience to a cue (conditioned stimulus, CS) paired with food reward (sign-trackers, STs), but the extent…”
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Limb use and complex ultrasonic vocalization in a rat model of Parkinson's disease: Deficit-targeted training
Published in Parkinsonism & related disorders (01-01-2008)“…Abstract Recent evidence in animal models of Parkinson's disease (PD) suggests that exercise and other forms of motor enhancement can be beneficial when…”
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