Search Results - "Ahrendt, Steven A"
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Serum microRNA biomarkers for detection of non-small cell lung cancer
Published in PloS one (28-02-2012)“…Non small cell lung cancer (NSCLC) is the leading cause of cancer-related mortality world-wide and the majority of cases are diagnosed at late stages of…”
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Clinicopathologic and molecular analysis of disseminated appendiceal mucinous neoplasms: identification of factors predicting survival and proposed criteria for a three-tiered assessment of tumor grade
Published in Modern pathology (01-11-2014)“…Previous studies have demonstrated that the prognosis of disseminated mucinous appendiceal neoplasms is highly dependent upon tumor grade. Reflecting this, the…”
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Tissue Factor Expression, Angiogenesis, and Thrombosis in Pancreatic Cancer
Published in Clinical cancer research (15-05-2007)“…Purpose: Hemostatic activation is common in pancreatic cancer and may be linked to angiogenesis and venous thromboembolism. We investigated expression of…”
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An integrated genome-wide approach to discover deregulated microRNAs in non-small cell lung cancer: Clinical significance of miR-23b-3p deregulation
Published in Scientific reports (28-08-2015)“…In spite of significant technical advances, genesis and progression of non-small cell lung cancer (NSCLC) remain poorly understood. We undertook an integrated…”
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GNAS is frequently mutated in both low-grade and high-grade disseminated appendiceal mucinous neoplasms but does not affect survival
Published in Human pathology (01-08-2014)“…Summary We analyzed a series of 55 disseminated appendiceal mucinous neoplasms treated at our institution for GNAS and KRAS mutations in an attempt to…”
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Gene Promoter Hypermethylation in Tumors and Lymph Nodes of Stage I Lung Cancer Patients
Published in Clinical cancer research (01-04-2003)“…Promoter hypermethylation is an important pathway for repression of gene transcription in cancer cells and a promising marker for cancer detection. We tested…”
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The p53 Codon 72 Proline Allele Is Associated with p53 Gene Mutations in Non–Small Cell Lung Cancer
Published in Clinical cancer research (01-04-2005)“…The p53 gene plays a critical role in cell cycle control, the initiation of apoptosis, and in DNA repair. An Arg/Pro polymorphism at codon 72 of the p53 gene…”
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Rapid p53 Sequence Analysis in Primary Lung Cancer Using an Oligonucleotide Probe Array
Published in Proceedings of the National Academy of Sciences - PNAS (22-06-1999)“…The p53 gene was sequenced in 100 primary human lung cancers by using direct dideoxynucleotide cycle sequencing and compared with sequence analysis by using…”
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Surgical Therapy of Iatrogenic Lesions of Biliary Tract
Published in World journal of surgery (01-10-2001)“… Iatrogenic injuries of the biliary tract have increased in incidence over the past decade with the introduction of laparoscopic cholecystectomy. Although a…”
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Thymidylate Synthase Expression Predicts the Response to 5-Fluorouracil-based Adjuvant Therapy in Pancreatic Cancer
Published in Clinical cancer research (15-09-2003)“…Purpose: Thymidylate synthase (TS) is the target enzyme for 5-fluorouracil (5-FU), and TS expression may determine clinical response and survival after therapy…”
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Dynamic Anthropometrics in Pancreatic Cancer: Associations Between Body Composition Changes During Neoadjuvant Therapy and Survival Outcomes After Resection
Published in Annals of surgical oncology (01-11-2024)“…Background Assessment of individual tumor biology and response to systemic therapy in pancreatic ductal adenocarcinoma (PDAC) remains a clinical challenge. The…”
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Radiologic Occult Metastases in Pancreatic Cancer: Analysis of Risk Factors and Survival Outcomes in the Age of Contemporary Neoadjuvant Multi-agent Chemotherapy
Published in Annals of surgical oncology (01-09-2024)“…Background Radiologic occult metastatic disease (ROMD) in patients with pancreatic ductal adenocarcinoma (PDAC) who undergo contemporary neoadjuvant…”
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Normal CEA Levels After Neoadjuvant Chemotherapy and Cytoreduction with Hyperthermic Intraperitoneal Chemoperfusion Predict Improved Survival from Colorectal Peritoneal Metastases
Published in Annals of surgical oncology (01-04-2024)“…Background Normal carcinoembryonic antigen (CEA) levels (≤ 2.5 ng/ml) after resection of localized colorectal cancer or liver metastases are associated with…”
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The Chicago Consensus on Peritoneal Surface Malignancies: Management of Appendiceal Neoplasms
Published in Annals of surgical oncology (01-06-2020)“…The Chicago Consensus Working Group provides multidisciplinary recommendations for the management of appendiceal neoplasms specifically related to the…”
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Solid Pseudopapillary Neoplasm: A Single Institutional Case Series of a Rare Pancreatic Tumor
Published in Journal of the advanced practitioner in oncology (01-07-2022)“…Solid pseudopapillary neoplasms (SPN) are rare pancreatic cystic neoplasms with low malignant potential that tend to occur in young women. Due to the rarity of…”
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Quality of Life Following Major Laparoscopic or Open Pancreatic Resection
Published in Annals of surgical oncology (01-09-2019)“…Purpose This study was designed to compare quality of life (QoL) among patients who underwent open versus laparoscopic pancreatic resection, including distal…”
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Implementation of Minimally Invasive Pancreaticoduodenectomy at Low and High-Volume Centers
Published in The Journal of surgical research (01-12-2021)“…There is a need to better define the safety of implementing the use of minimally invasive pancreaticoduodenectomy (MIPD) in order to provide evidence for safe…”
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The Chicago Consensus on Peritoneal Surface Malignancies: Management of Colorectal Metastases
Published in Annals of surgical oncology (01-06-2020)“…The Chicago Consensus Working Group provides multidisciplinary recommendations for the management of colorectal cancer specifically as it relates to the…”
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