Search Results - "Aho, Johanna"

Mutation update for the ACTN2 gene by Ranta‐aho, Johanna, Olive, Montse, Vandroux, Marie, Roticiani, Giorgia, Dominguez, Cristina, Johari, Mridul, Torella, Annalaura, Böhm, Johann, Turon, Janina, Nigro, Vincenzo, Hackman, Peter, Laporte, Jocelyn, Udd, Bjarne, Savarese, Marco

“…ACTN2 encodes alpha‐actinin‐2, a protein expressed in human cardiac and skeletal muscle. The protein, located in the sarcomere Z‐disk, functions as a link…”
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Roadmap to 3D-Printed Oral Pharmaceutical Dosage Forms: Feedstock Filament Properties and Characterization for Fused Deposition Modeling by Aho, Johanna, Bøtker, Johan Peter, Genina, Natalja, Edinger, Magnus, Arnfast, Lærke, Rantanen, Jukka

“…Application of additive manufacturing techniques (3D printing) for mass-customized products has boomed in the recent years. In pharmaceutical industry and…”
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Melt Extrusion of High-Dose Co-Amorphous Drug-Drug Combinations by Arnfast, Lærke, Kamruzzaman, Md, Löbmann, Korbinian, Aho, Johanna, Baldursdottir, Stefania, Rades, Thomas, Rantanen, Jukka

“…Purpose Many future drug products will be based on innovative manufacturing solutions, which will increase the need for a thorough understanding of the…”
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Protein‐extending ACTN2 frameshift variants cause variable myopathy phenotypes by protein aggregation by Ranta‐aho, Johanna, Felice, Kevin J., Jonson, Per Harald, Sarparanta, Jaakko, Yvorel, Cédric, Harzallah, Ines, Touraine, Renaud, Pais, Lynn, Austin‐Tse, Christina A., Ganesh, Vijay S., O'Leary, Melanie C., Rehm, Heidi L., Hehir, Michael K., Subramony, Sub, Wu, Qian, Udd, Bjarne, Savarese, Marco

“…Objective The objective of the study is to characterize the pathomechanisms underlying actininopathies. Distal myopathies are a group of rare, inherited…”
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On the measurement and modeling of viscosity of polymers at low temperatures by Aho, Johanna, Syrjälä, Seppo

“…Viscosity was measured for three amorphous polymers, PS, PMMA and PC, down to temperatures well below those normally available. Measurements were made in the…”
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Exploring the Complexity of Processing-Induced Dehydration during Hot Melt Extrusion Using In-Line Raman Spectroscopy by Arnfast, Lærke, van Renterghem, Jeroen, Aho, Johanna, Bøtker, Johan, Raijada, Dhara, Baldursdóttir, Stefania, De Beer, Thomas, Rantanen, Jukka

“…The specific aim in this study was to understand the effect of critical process parameters on the solid form composition of model drug compounds during hot…”
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Capillary rheometry of polymer melts — Simulation and experiment by Syrjälä, Seppo, Aho, Johanna

“…This paper discusses shear viscosity measurements of polymer melts by the capillary rheometer. Particular emphasis is placed on investigating the effects of…”
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In silico product design of pharmaceuticals by Boetker, Johan, Raijada, Dhara, Aho, Johanna, Khorasani, Milad, Søgaard, Søren V., Arnfast, Lærke, Bohr, Adam, Edinger, Magnus, Water, Jorrit J., Rantanen, Jukka

“…The increasing demand for personalized medicine necessitates the production of easily customizable dosage forms. As the number of possible dosage forms may…”
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Capillary rheometry of polymer melts - Simulation and experiment by Syrjala, Seppo, Aho, Johanna

“…This paper discusses shear viscosity measurements of polymer melts by the capillary rheometer. Particular emphasis is placed on investigating the effects of…”
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Evaluation of Different Methods for Determining the Entrance Pressure Drop in Capillary Rheometry by Aho Johanna, Syrjälä Seppo

“…Two approaches for determining the entrance pressure drop in capillary rheometry were compared with low-density polyethylene and polystyrene melts as test…”
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Rheology: A cross-disciplinary technology evolving to take on new challenges (22nd Nordic Rheology Conference 2013) by Madsen Claus Greve, Aho Johanna, Featherston David Wray, Baldursdottir Stefania

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Current advance on distal myopathy genetics by Ranta-Aho, Johanna, Johari, Mridul, Udd, Bjarne

“…Distal myopathies are a clinically heterogenous group of rare, genetic muscle diseases, that present with weakness in hands and/or feet at onset. Some of these…”
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Modifying release characteristics from 3D printed drug-eluting products by Boetker, Johan, Water, Jorrit Jeroen, Aho, Johanna, Arnfast, Lærke, Bohr, Adam, Rantanen, Jukka

“…This work describes an approach to modify the release of active compound from a 3D printed model drug product geometry intended for flexible dosing and…”
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Rheology as a tool for evaluation of melt processability of innovative dosage forms by Aho, Johanna, Boetker, Johan P., Baldursdottir, Stefania, Rantanen, Jukka

“…[Display omitted] Future manufacturing of pharmaceuticals will involve innovative use of polymeric excipients. Hot melt extrusion (HME) is an already…”
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Oscillatory Shear Rheology in Examining the Drug-Polymer Interactions Relevant in Hot Melt Extrusion by Aho, Johanna, Edinger, Magnus, Botker, Johan, Baldursdottir, Stefania, Rantanen, Jukka

“…The flow properties of drug-polymer mixtures have a significant influence on their processability when using techniques such as hot melt extrusion (HME)…”
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Three-dimensional printing of drug-eluting implants: preparation of an antimicrobial polylactide feedstock material by Water, Jorrit Jeroen, Bohr, Adam, Boetker, Johan, Aho, Johanna, Sandler, Niklas, Nielsen, Hanne Mørck, Rantanen, Jukka

“…The aim of the present work was to investigate the potential of three-dimensional (3D) printing as a manufacturing method for products intended for…”
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Near-infrared chemical imaging (NIR-CI) of 3D printed pharmaceuticals by Khorasani, Milad, Edinger, Magnus, Raijada, Dhara, Bøtker, Johan, Aho, Johanna, Rantanen, Jukka

“…[Display omitted] Hot-melt extrusion and 3D printing are enabling manufacturing approaches for patient-centred medicinal products. Hot-melt extrusion is a…”
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Melt Extrusion of High-Dose Co-Amorphous Drug-Drug Combinations: Theme: Formulation and Manufacturing of Solid Dosage Forms Guest Editors: Tony Zhou and Tonglei Li by Arnfast, Lærke, Kamruzzaman, Md, Löbmann, Korbinian, Aho, Johanna, Baldursdottir, Stefania, Rades, Thomas, Rantanen, Jukka

“…Purpose Many future drug products will be based on innovative manufacturing solutions, which will increase the need for a thorough understanding of the…”
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Electrospinnability of Poly Lactic-co-glycolic Acid (PLGA): the Role of Solvent Type and Solvent Composition by Liu, Xiaoli, Baldursdottir, Stefania G., Aho, Johanna, Qu, Haiyan, Christensen, Lars Porskjær, Rantanen, Jukka, Yang, Mingshi

“…ABSTRACT Purpose In this study, the electrospinnability of poly(lactic-co-glycolic acid) (PLGA) solutions was investigated, with a focus on understanding the…”
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Measurement of the pressure dependence of viscosity of polymer melts using a back pressure-regulated capillary rheometer by Aho, Johanna, Syrjälä, Seppo

“…The effect of pressure on the melt viscosity was experimentally investigated for five polymers: polycarbonate (PC), acrylonitrile-butadiene-styrene (ABS),…”
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