Search Results - "Ahnn, Joohong"

Regulator of Calcineurin (RCAN): Beyond Down Syndrome Critical Region by Lee, Sun-Kyung, Ahnn, Joohong

“…The regulator of calcineurin (RCAN) was first reported as a novel gene called DSCR1, encoded in a region termed the Down syndrome critical region (DSCR) of…”
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Human Endogenous Retroviruses as Gene Expression Regulators: Insights from Animal Models into Human Diseases by Durnaoglu, Serpen, Lee, Sun-Kyung, Ahnn, Joohong

“…The human genome contains many retroviral elements called human endogenous retroviruses (HERVs), resulting from the integration of retroviruses throughout…”
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Human Endogenous Retroviruses: Friends and Foes in Urology Clinics by Lee, Sun-Kyung, Kim, Seung Hyun, Ahnn, Joohong

“…Human endogenous retroviruses (HERVs) are originated from ancient exogenous retroviruses, which infected human germ line cells millions of years ago. HERVs…”
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Syncytin, envelope protein of human endogenous retrovirus (HERV): no longer 'fossil' in human genome by Durnaoglu, Serpen, Lee, Sun-Kyung, Ahnn, Joohong

“…Human endogenous retroviruses (HERVs) are 'fossil viruses' that resulted from stable integrations of exogenous retroviruses throughout evolution. HERVs are…”
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Loss of Calreticulin Uncovers a Critical Role for Calcium in Regulating Cellular Lipid Homeostasis by Wang, Wen-An, Liu, Wen-Xin, Durnaoglu, Serpen, Lee, Sun-Kyung, Lian, Jihong, Lehner, Richard, Ahnn, Joohong, Agellon, Luis B., Michalak, Marek

“…A direct link between Ca 2+ and lipid homeostasis has not been definitively demonstrated. In this study, we show that manipulation of ER Ca 2+ causes the…”
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Human Endogenous Retrovirus K (HERV-K) can drive gene expression as a promoter in Caenorhabditis elegans by Durnaoglu, Serpen, Kim, Heui-Soo, Ahnn, Joohong, Lee, Sun-Kyung

“…Endogenous retroviruses (ERVs) are retrotransposons present in various metazoan genomes and have been implicated in metazoan evolution as well as in nematodes…”
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Interplay between the oxidoreductase PDIA6 and microRNA-322 controls the response to disrupted endoplasmic reticulum calcium homeostasis by Groenendyk, Jody, Peng, Zhenling, Dudek, Elzbieta, Fan, Xiao, Mizianty, Marcin J, Dufey, Estefanie, Urra, Hery, Sepulveda, Denisse, Rojas-Rivera, Diego, Lim, Yunki, Kim, Do Han, Baretta, Kayla, Srikanth, Sonal, Gwack, Yousang, Ahnn, Joohong, Kaufman, Randal J, Lee, Sun-Kyung, Hetz, Claudio, Kurgan, Lukasz, Michalak, Marek

“…The disruption of the energy or nutrient balance triggers endoplasmic reticulum (ER) stress, a process that mobilizes various strategies, collectively called…”
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Morphological Characterization of small, dumpy, and long Phenotypes in Caenorhabditis elegans by Cho, Joshua Young, Choi, Tae-Woo, Kim, Seung Hyun, Ahnn, Joohong, Lee, Sun-Kyung

“…The determinant factors of an organism’s size during animal development have been explored from various angles but remain partially understood. In…”
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Botulinum Toxin as a Pain Killer: Players and Actions in Antinociception by Kim, Dong-Wan, Lee, Sun-Kyung, Ahnn, Joohong

“…Botulinum neurotoxins (BoNTs) have been widely used to treat a variety of clinical ailments associated with pain. The inhibitory action of BoNTs on synaptic…”
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Novel Findings of Anti-Filarial Drug Target and Structure-Based Virtual Screening for Drug Discovery by Choi, Tae-Woo, Cho, Jeong Hoon, Ahnn, Joohong, Song, Hyun-Ok

“…Lymphatic filariasis and onchocerciasis caused by filarial nematodes are important diseases leading to considerable morbidity throughout tropical countries…”
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Dicarbonyl/L-xylulose reductase (DCXR) producing xylitol regulates egg retention through osmolality control in Caenorhabditis elegans by Kim, Yuh-Nam, Kim, Seung Hyun, Son, Le Tho, Ahnn, Joohong, Lee, Sun-Kyung

“…To support life, the osmolality of the cellular fluid is tightly regulated by various means, including osmolyte control. Dicarbonyl/L-xylulose reductase (DCXR)…”
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Allele-Specific Phenotype Suggests a Possible Stimulatory Activity of RCAN-1 on Calcineurin in Caenorhabditis elegans by Li, Weixun, Choi, Tae-Woo, Ahnn, Joohong, Lee, Sun-Kyung

“…Regulator of calcineurin 1 (RCAN1) binds to calcineurin through the PxIxIT motif, which is evolutionarily conserved. SP repeat phosphorylation in RCAN1 is…”
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Autophagy genes mediate the effect of calcineurin on life span in C. elegans by Dwivedi, Meenakshi, Song, Hyun-Ok, Ahnn, Joohong

“…Calcineurin (CaN) is a serine/threonine phosphatase, activated by Ca2+/calmodulin (Ca2+/CaM). CaN is known to regulate various cellular responses in different…”
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Pharmacological activation of Sirt1 ameliorates polyglutamine-induced toxicity through the regulation of autophagy by Shin, Bae Hyun, Lim, Yunki, Oh, Hye Jin, Park, Sang Min, Lee, Sun-Kyung, Ahnn, Joohong, Kim, Do Han, Song, Woo Keun, Kwak, Tae Hwan, Park, Woo Jin

“…Intracellular accumulation of polyglutamine (polyQ)-expanded Huntingtin (Htt) protein is a hallmark of Huntington's disease (HD). This study evaluated whether…”
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Morphological Characterization of small, dumpy, and long Phenotypes in Caenorhabditis elegans by Cho, Joshua Young, Choi, Tae-Woo, Kim, Seung Hyun, Ahnn, Joohong, Lee, Sun-Kyung

“…The determinant factors of an organism's size during animal development have been explored from various angles but remain partially understood. In…”
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Calcineurin tax-6 regulates male ray development and counteracts with kin-29 kinase in Caenorhabditis elegans by Kim, Seung Hyun, Jung, Hana, Ahnn, Joohong, Lee, Sun-Kyung

“…Phosphorylation is one of the critical protein modifications, which can lead to changing the activity of the proteins and regulating a variety of biological…”
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Human Endogenous Retrovirus K (HERV-K) can drive gene expression as a promoter in Caenorhabditis elegans by Durnaoglu, Serpen, Kim, Heui-Soo, Ahnn, Joohong, Lee, Sun-Kyung

“…Endogenous retroviruses (ERVs) are retrotransposons present in various metazoan genomes and have been implicated in metazoan evolution as well as in nematodes…”
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PYP-1, inorganic pyrophosphatase, is required for larval development and intestinal function in C. elegans by Ko, Kyung Min, Lee, Wonhae, Yu, Jae-Ran, Ahnn, Joohong

“…Inorganic pyrophosphatase (PPase) catalyzes the hydrolysis of inorganic pyrophosphate (PPi) into phosphate (Pi), which provides a thermodynamic driving force…”
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C. elegans STI-1, the Homolog of Sti1/Hop, Is Involved in Aging and Stress Response by Song, Hyun-Ok, Lee, Wonhae, An, Kiyoung, Lee, Hye-suk, Cho, Jeong Hoon, Park, Zee-Yong, Ahnn, Joohong

“…Environmental and physiological stresses such as heat shock, oxidative stress, heavy metals, and pathogenic conditions induce cellular stress response. This…”
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Allele-Specific Phenotype Suggests a Possible Stimulatory Activity of RCAN-1 on Calcineurin in Caenorhabditis elegans by Li, Weixun, Choi, Tae-Woo, Ahnn, Joohong, Lee, Sun-Kyung

“…Regulator of calcineurin 1 (RCAN1) binds to calcineurin through the PxIxIT motif, which is evolutionarily conserved. SP repeat phosphorylation in RCAN1 is…”
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