Search Results - "Ahn, Yeseul"

A Semi-Physiological Three-Compartment Model Describes Brain Uptake Clearance and Efflux of Sucrose and Mannitol after IV Injection in Awake Mice by Noorani, Behnam, Chowdhury, Ekram Ahmed, Alqahtani, Faleh, Sajib, Md Sanaullah, Ahn, Yeseul, Nozohouri, Ehsan, Patel, Dhavalkumar, Mikelis, Constantinos, Mehvar, Reza, Bickel, Ulrich

“…Purpose To evaluate a three-compartmental semi-physiological model for analysis of uptake clearance and efflux from brain tissue of the hydrophilic markers…”
Get full text

LC–MS/MS-based in vitro and in vivo investigation of blood–brain barrier integrity by simultaneous quantitation of mannitol and sucrose by Noorani, Behnam, Chowdhury, Ekram Ahmed, Alqahtani, Faleh, Ahn, Yeseul, Patel, Dhavalkumar, Al-Ahmad, Abraham, Mehvar, Reza, Bickel, Ulrich

“…Background Understanding the pathophysiology of the blood brain-barrier (BBB) plays a critical role in diagnosis and treatment of disease conditions. Applying…”
Get full text

Uptake Transporters at the Blood–Brain Barrier and Their Role in Brain Drug Disposition by Parvez, Md Masud, Sadighi, Armin, Ahn, Yeseul, Keller, Steve F, Enoru, Julius O

“…Uptake drug transporters play a significant role in the pharmacokinetic of drugs within the brain, facilitating their entry into the central nervous system…”
Get full text

Advanced Microfluidic Vascularized Tissues as Platform for the Study of Human Diseases and Drug Development by Noorani, Behnam, Cucullo, Luca, Ahn, Yeseul, Kadry, Hossam, Bhalerao, Aditya, Raut, Snehal, Nozohouri, Ehsan, Chowdhury, Ekram Ahmed

“…The vascular system plays a critical role in human physiology and diseases. It is a complex subject to study using in vitro models due to its dynamic and…”
Get full text

Higher Brain Uptake of Gentamicin and Ceftazidime under Isoflurane Anesthesia Compared to Ketamine/Xylazine by Ahn, Yeseul, Patil, Chanakya D, Nozohouri, Ehsan, Zoubi, Sumaih, Patel, Dhavalkumar, Bickel, Ulrich

“…We have recently shown that the volatile anesthetics isoflurane and sevoflurane acutely enhance the brain uptake of the hydrophilic markers sucrose and…”
Get full text

Systemic and Brain Pharmacokinetics of Milnacipran in Mice: Comparison of Intraperitoneal and Intravenous Administration by Bagchi, Sounak, Nozohouri, Ehsan, Ahn, Yeseul, Patel, Dhavalkumar, Bickel, Ulrich, Karamyan, Vardan T

“…Milnacipran is a dual serotonin and norepinephrine reuptake inhibitor, clinically used for the treatment of major depression or fibromyalgia. Currently, there…”
Get full text

Impact of in-utero electronic cigarette exposure on neonatal neuroinflammation, oxidative stress and mitochondrial function by Archie, Sabrina Rahman, Sifat, Ali Ehsan, Mara, David, Ahn, Yeseul, Akter, Khondker Ayesha, Zhang, Yong, Cucullo, Luca, Abbruscato, Thomas J.

“…Introduction: Despite the prevalence of the perception that electronic cigarettes (e-cig) are a safer alternative to tobacco smoke, growing concern about their…”
Get full text

Efficacy and Safety of Innovative Experimental Chimeric Antigen Receptor (CAR) T-cells versus Axicabtagene ciloleucel (Yescarta) for the Treatment of Relapsed/Refractory Large B-Cell Lymphoma (LBCL): Matching Adjusted Indirect Comparisons (MAICs) and Systematic Review by Weinstein, Bayarmagnai, Muresan, Bogdan, Solano, Sara, de Macedo, Antonio Vaz, Lee, YoonJung, Su, Yu-Chen, Ahn, Yeseul, Henriquez, Gabriela, Camargo, Cristina, Kim, Gwang-Jin, Carpenter, David O

“…Despite favorable results of CAR T-cell therapy for relapsed/refractory large B-cell lymphoma (R/R LBCL), several challenges remain, including incomplete…”
Get full text

Impact of Physical Activity and Medication Adherence on the Seizure Frequency and Quality of Life of Epileptic Patients: A Population Study in West Texas by Lee, YoonJung, Ahn, Yeseul, Cucullo, Luca

“…Epilepsy is a neurological disease that affects 1-3% of the population. People with epilepsy (PWE) have poor physical and psychological health and a lower…”
Get full text

68 Characterization of Bovine Extracellular Vesicles Isolated from Colostrum by Brown, Audrey, Santos, Rafaela, Ahn, Yeseul, Bickel, Ulrich, Rosa, Fernanda

“…Abstract Bovine colostrum is composed of a variety of biologically active compounds including microRNAs (miRNA), which are found within extracellular vesicles…”
Get full text

ULK1 phosphorylates Ser30 of BECN1 in association with ATG14 to stimulate autophagy induction by Park, Ji-Man, Seo, Minchul, Jung, Chang Hwa, Grunwald, Douglas, Stone, Matthew, Otto, Neil Michael, Toso, Erik, Ahn, Yeseul, Kyba, Michael, Griffin, Timothy J., Higgins, LeeAnn, Kim, Do-Hyung

“…ULK1 (unc51-like autophagy activating kinase 1) is a serine/threonine kinase that plays a key role in regulating macroautophagy/autophagy induction in response…”
Get full text

The Acute Impact of Propofol on Blood–Brain Barrier Integrity in Mice by Nozohouri, Ehsan, Ahn, Yeseul, Zoubi, Sumaih, Patel, Dhavalkumar, Archie, Sabrina Rahman, Akter, Khondker Ayesha, Siddique, Muhammad Bilal, Huang, Juyang, Abbruscato, Thomas J., Bickel, Ulrich

“…Purpose We investigated whether short term infusion of propofol, a highly lipophilic agonist at GABA A receptors, which is in widespread clinical use as…”
Get full text

Effects of Volatile Anesthetics versus Ketamine on Blood-Brain Barrier Permeability via Lipid-Mediated Alterations of Endothelial Cell Membranes by Noorani, Behnam, Chowdhury, Ekram Ahmed, Alqahtani, Faleh, Ahn, Yeseul, Nozohouri, Ehsan, Zoubi, Sumaih, Patel, Dhavalkumar, Wood, Laurence, Huang, Juyang, Siddique, Muhammad Bilal, Al-Ahmad, Abraham, Mehvar, Reza, Bickel, Ulrich

“…The purpose of this study was to investigate the effects of the volatile anesthetic agents isoflurane and sevoflurane, at clinically relevant concentrations,…”
Get full text

Copper foil exposed structure for thin PoP warpage improvement by YeSeul Ahn, JinSeong Kim, ChaGyu Song, GyuWan Han, JuHoon Yoon, ChoonHeung Lee

“…Advanced flip chip packaging technology supports the next generation of products with increased die complexities. The increase in complexity and functionality…”
Get full text