Search Results - "Ahn, Susie"
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Predicting in vitro drug sensitivity using Random Forests
Published in Bioinformatics (15-01-2011)“…Panels of cell lines such as the NCI-60 have long been used to test drug candidates for their ability to inhibit proliferation. Predictive models of in vitro…”
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2
Unsupervised Analysis of Transcriptomic Profiles Reveals Six Glioma Subtypes
Published in Cancer research (Chicago, Ill.) (01-03-2009)“…Gliomas are the most common type of primary brain tumors in adults and a significant cause of cancer-related mortality. Defining glioma subtypes based on…”
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Genomic changes and gene expression profiles reveal that established glioma cell lines are poorly representative of primary human gliomas
Published in Molecular cancer research (01-01-2008)“…Genetic aberrations, such as gene amplification, deletions, and loss of heterozygosity, are hallmarks of cancer and are thought to be major contributors to the…”
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4
Epigenetic-Mediated Dysfunction of the Bone Morphogenetic Protein Pathway Inhibits Differentiation of Glioblastoma-Initiating Cells
Published in Cancer cell (01-01-2008)“…Despite similarities between tumor-initiating cells with stem-like properties (TICs) and normal neural stem cells, we hypothesized that there may be…”
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Inositol Polyphosphate-5-Phosphatase F (INPP5F) inhibits STAT3 activity and suppresses gliomas tumorigenicity
Published in Scientific reports (05-12-2014)“…Glioblastoma (GBM), the most common type of primary malignant brain tumors harboring a subpopulation of stem-like cells (GSCs), is a fast-growing and often…”
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6
Identification of molecular pathways facilitating glioma cell invasion in situ
Published in PloS one (03-11-2014)“…Gliomas are mostly incurable secondary to their diffuse infiltrative nature. Thus, specific therapeutic targeting of invasive glioma cells is an attractive…”
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Prediction of Associations between microRNAs and Gene Expression in Glioma Biology
Published in PloS one (16-02-2011)“…Despite progress in the determination of miR interactions, their regulatory role in cancer is only beginning to be unraveled. Utilizing gene expression data…”
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8
Micro-environment causes reversible changes in DNA methylation and mRNA expression profiles in patient-derived glioma stem cells
Published in PloS one (01-04-2014)“…In vitro and in vivo models are widely used in cancer research. Characterizing the similarities and differences between a patient's tumor and corresponding in…”
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G-cimp status prediction of glioblastoma samples using mRNA expression data
Published in PloS one (06-11-2012)“…Glioblastoma Multiforme (GBM) is a tumor with high mortality and no known cure. The dramatic molecular and clinical heterogeneity seen in this tumor has led to…”
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10
Identification of competence pheromone responsive genes in Streptococcus pneumoniae by use of DNA microarrays
Published in Molecular microbiology (01-02-2004)“…Summary Natural genetic transformation in Streptococcus pneumoniae is controlled in part by a quorum‐sensing system mediated by a peptide pheromone called…”
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Metabolic plasticity of IDH1 -mutant glioma cell lines is responsible for low sensitivity to glutaminase inhibition
Published in Cancer & metabolism (21-10-2020)“…Targeting glutamine metabolism in cancer has become an increasingly vibrant area of research. Mutant IDH1 (IDH1 ) gliomas are considered good candidates for…”
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CTIM-06. EVALUATING THE ASSOCIATION BETWEEN PERIPHERAL BLOOD IMMUNOLOGIC RESPONSE AND THERAPEUTIC RESPONSE TO IMMUNE CHECKPOINT INHIBITION IN PATIENTS WITH NEWLY DIAGNOSED GLIOBLASTOMA AND GLIOSARCOMA
Published in Neuro-oncology (Charlottesville, Va.) (14-11-2022)“…Abstract Immune checkpoint inhibition (ICI) has failed to demonstrate significant efficacy in glioblastoma. With the underlying hypothesis that generation of…”
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Detailed longitudinal sampling of glioma stem cells in situ reveals Chr7 gain and Chr10 loss as repeated events in primary tumor formation and recurrence
Published in International journal of cancer (15-11-2017)“…Intratumoral heterogeneity at the genetic, epigenetic, transcriptomic, and morphologic levels is a commonly observed phenomenon in many aggressive cancer…”
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Emergency Department Patients are Receptive to Prayer-Based Interventions to Reduce Alcohol Use
Published in Journal of religion and health (01-08-2020)“…Previous studies show that elements of spirituality, including prayer and religious services, may contribute to reductions in harmful alcohol use. The…”
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Purification and Characterization of a Cytotonic Protein Expressed In Vitro by the Live Cholera Vaccine Candidate CVD 103-HgR
Published in Infection and Immunity (01-10-2000)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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A Core Regulatory Circuit in Glioblastoma Stem Cells Links MAPK Activation to a Transcriptional Program of Neural Stem Cell Identity
Published in Scientific reports (03-03-2017)“…Glioblastoma, the most common primary malignant brain tumor, harbors a small population of tumor initiating cells (glioblastoma stem cells) that have many…”
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Adjuvant therapy for early stage, endometrial cancer with lymphovascular space invasion: Is there a role for chemotherapy?
Published in Gynecologic oncology (01-03-2020)“…Lymphovascular space invasion (LVSI) is an independent risk factor for recurrence and poor survival in early-stage endometrioid endometrial cancer (EEC), but…”
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Abstract A019: Phase II trial evaluating the association of peripheral blood immunologic response and therapeutic response to immune checkpoint inhibition in patients with newly diagnosed glioblastoma and gliosarcoma
Published in Cancer research (Chicago, Ill.) (04-03-2024)“…Abstract Background: Glioblastoma and gliosarcoma are highly aggressive, Grade IV CNS malignancies with notoriously immunosuppressive tumor microenvironments…”
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CBIO-11. UPREGULATION OF THE TGF-β PATHWAY DRIVES TRANSFORMATION OF GLIOBLASTOMA INTO GLIOSARCOMA AND OSTEOSARCOMA
Published in Neuro-oncology (Charlottesville, Va.) (06-11-2017)Get full text
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TGF-β and BMP signaling are associated with the transformation of glioblastoma to gliosarcoma and then osteosarcoma
Published in Neuro-oncology advances (01-01-2024)“…Abstract Background Gliosarcoma, an isocitrate dehydrogenase wildtype (IDH-WT) variant of glioblastoma, is defined by clonal biphasic differentiation into…”
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