Search Results - "Ahn, Jung‐Hyuck"

Ahnak scaffolds p11/Anxa2 complex and L-type voltage-gated calcium channel and modulates depressive behavior by Jin, Junghee, Bhatti, Dionnet L., Lee, Ko-Woon, Medrihan, Lucian, Cheng, Jia, Wei, Jing, Zhong, Ping, Yan, Zhen, Kooiker, Cassandra, Song, Claire, Ahn, Jung-Hyuck, Obermair, Gerald J., Lee, Amy, Gresack, Jodi, Greengard, Paul, Kim, Yong

“…Genetic polymorphisms of the L-type voltage-gated calcium channel (VGCC) are associated with psychiatric disorders including major depressive disorder…”
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Protective role of ABCA1 in ischemic preconditioning is mediated by downregulation of miR-33-5p and miR-135-5p by Sung, Hye Youn, Choi, Eun Nam, Han, Jihye, Chae, Yun Ju, Im, Sun-Wha, Kim, Hee-Sun, Park, Eun-Mi, Ahn, Jung-Hyuck

“…Ischemic preconditioning (IPC) significantly reduces ischemia–reperfusion injury in the brain by inducing ischemic tolerance. Although emerging evidence…”
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Protein kinase A activates protein phosphatase 2A by phosphorylation of the B56δ subunit by Ahn, Jung-Hyuck, McAvoy, Thomas, Rakhilin, Sergey V, Nishi, Akinori, Greengard, Paul, Nairn, Angus C

“…Our previous studies of DARPP-32 in striatal slices have shown that activation of D1 receptors leads to cAMP-dependent dephosphorylation of Thr-75, the Cdk5…”
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Epigenome-wide association study of diabetic chronic kidney disease progression in the Korean population: the KNOW-CKD study by Sung, Hye Youn, Lee, Sangjun, Han, Miyeun, An, Woo Ju, Ryu, Hyunjin, Kang, Eunjeong, Park, Yong Seek, Lee, Seung Eun, Ahn, Curie, Oh, Kook-Hwan, Park, Sue K., Ahn, Jung-Hyuck

“…Since the etiology of diabetic chronic kidney disease (CKD) is multifactorial, studies on DNA methylation for kidney function deterioration have rarely been…”
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SMARCA3, a Chromatin-Remodeling Factor, Is Required for p11-Dependent Antidepressant Action by Oh, Yong-Seok, Gao, Pu, Lee, Ko-Woon, Ceglia, Ilaria, Seo, Ji-Seon, Zhang, Xiaozhu, Ahn, Jung-Hyuck, Chait, Brian T., Patel, Dinshaw J., Kim, Yong, Greengard, Paul

“…p11, through unknown mechanisms, is required for behavioral and cellular responses to selective serotonin reuptake inhibitors (SSRIs). We show that SMARCA3, a…”
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Role of Treg and TH17 Cells of the Gastric Mucosa in Children With Helicobacter pylori Gastritis by Gil, Joo Hyun, Seo, Jeong Wan, Cho, Min-Sun, Ahn, Jung-Hyuck, Sung, Hye Youn

“…ABSTRACT Objective: The aim of the present study was to examine the expression of FOXP3, interleukin (IL)‐10, transforming growth factor (TGF)‐β1, IL‐17A, and…”
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Ablation of ceramide synthase 2 exacerbates dextran sodium sulphate‐induced colitis in mice due to increased intestinal permeability by Kim, Ye‐Ryung, Volpert, Giora, Shin, Kyong‐Oh, Kim, So‐Yeon, Shin, Sun‐Hye, Lee, Younghay, Sung, Sun Hee, Lee, Yong‐Moon, Ahn, Jung‐Hyuck, Pewzner‐Jung, Yael, Park, Woo‐Jae, Futerman, Anthony H., Park, Joo‐Won

“…Ceramides mediate crucial cellular processes including cell death and inflammation and have recently been implicated in inflammatory bowel disease. Ceramides…”
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A phosphatase cascade by which rewarding stimuli control nucleosomal response by Girault, Jean-Antoine, Stipanovich, Alexandre, Valjent, Emmanuel, Matamales, Miriam, Nishi, Akinori, Ahn, Jung-Hyuck, Maroteaux, Matthieu, Bertran-Gonzalez, Jesus, Brami-Cherrier, Karen, Enslen, Hervé, Corbillé, Anne-Gaëlle, Filhol, Odile, Nairn, Angus C, Greengard, Paul, Hervé, Denis

“…Appetite and drug addiction Disruptions in dopamine signalling have been implicated in psychiatric disorders, such as schizophrenia and drug addiction. The…”
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Amyloid Beta-Mediated Hypomethylation of Heme Oxygenase 1 Correlates with Cognitive Impairment in Alzheimer's Disease by Sung, Hye Youn, Choi, Byung-Ok, Jeong, Jee Hyang, Kong, Kyoung Ae, Hwang, Jinha, Ahn, Jung-Hyuck

“…To identify epigenetically regulated genes involved in the pathogenesis of Alzheimer's disease (AD) we analyzed global mRNA expression and methylation profiles…”
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Phosphorylation of WAVE1 regulates actin polymerization and dendritic spine morphology by Ceglia, Ilaria, Kwak, Seung P, Bardoni, Barbara, Ho Ryu, Sung, Greengard, Paul, Sung, Jee Young, Kim, Amie M, Kim, Yong, Scott, John D, Lee, Ko-Woon, Halford, Jonathan M, Park, Jong Bae, Schenck, Annette, Nairn, Angus C, Ahn, Jung-Hyuck

“…WAVE1—the Wiskott–Aldrich syndrome protein (WASP)-family verprolin homologous protein 1—is a key regulator of actin-dependent morphological processes in…”
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C16‑ceramide and sphingosine 1‑phosphate/S1PR2 have opposite effects on cell growth through mTOR signaling pathway regulation by Kim, Min Hee, Park, Joo-Won, Lee, Eun-Ji, Kim, Shin, Shin, Sun-Hye, Ahn, Jung-Hyuck, Jung, Yunjae, Park, Inkeun, Park, Woo-Jae

“…Recently, sphingolipid derivatives, such as ceramide and sphingosine‑1‑phosphate (S1P), have emerged as key modulators in apoptotic cell death and cell…”
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Autophagy induction in the skeletal myogenic differentiation of human tonsil-derived mesenchymal stem cells by Park, Saeyoung, Choi, Yoonyoung, Jung, Namhee, Kim, Jieun, Oh, Seiyoon, Yu, Yeonsil, Ahn, Jung-Hyuck, Jo, Inho, Choi, Byung-Ok, Jung, Sung-Chul

“…Mesenchymal stem cells (MSCs) are capable of self-renewal and differentiation and are thus a valuable source for the replacement of diseased or damaged organs…”
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Amyloid beta-mediated epigenetic alteration of insulin-like growth factor binding protein 3 controls cell survival in Alzheimer's disease by Sung, Hye Youn, Choi, Eun Nam, Lyu, Dahyun, Mook-Jung, Inhee, Ahn, Jung-Hyuck

“…Swedish double mutation (KM670/671NL) of amyloid precursor protein (APP) is reported to increase toxic amyloid β (Aβ) production via aberrant cleavage at the…”
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Identification of Serum Metabolites for Predicting Chronic Kidney Disease Progression according to Chronic Kidney Disease Cause by Kang, Eunjeong, Li, Yufei, Kim, Bora, Huh, Ki Young, Han, Miyeun, Ahn, Jung-Hyuck, Sung, Hye Youn, Park, Yong Seek, Lee, Seung Eun, Lee, Sangjun, Park, Sue K, Cho, Joo-Youn, Oh, Kook-Hwan

“…Early detection and proper management of chronic kidney disease (CKD) can delay progression to end-stage kidney disease. We applied metabolomics to discover…”
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Regulatory B Subunits of Protein Phosphatase 2A Are Involved in Site-specific Regulation of Tau Protein Phosphorylation by Yu, Un Young, Yoo, Byong Chul, Ahn, Jung-Hyuck

“…Overexpression of amyloid precursor protein with the Swedish mutation causes abnormal hyperphosphorylation of the microtubule-associated protein tau…”
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Aberrant DNA methylation in the IFITM1 promoter enhances the metastatic phenotype in an intraperitoneal xenograft model of human ovarian cancer by KIM, NAM HEE, SUNG, HYE YOUN, CHOI, EUN NAM, LYU, DAHYUN, CHOI, HYUCK JAE, JU, WOONG, AHN, JUNG-HYUCK

“…A lack of reliable biomarkers for the early detection and risk of metastatic recurrences makes ovarian cancer the most lethal gynecological cancer. To…”
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Protein kinase C-dependent dephosphorylation of tyrosine hydroxylase requires the B56δ heterotrimeric form of protein phosphatase 2A by Ahn, Jung-Hyuck, Kim, Yong, Kim, Hee-Sun, Greengard, Paul, Nairn, Angus C

“…Tyrosine hydroxylase, which plays a critical role in regulation of dopamine synthesis, is known to be controlled by phosphorylation at several critical sites…”
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Overexpression of mucin 13 due to promoter methylation promotes aggressive behavior in ovarian cancer cells by Sung, Hye Youn, Park, Ae Kyung, Ju, Woong, Ahn, Jung-Hyuck

“…Recent discoveries suggest that aberrant DNA methylation provides cancer cells with advanced metastatic properties. However, the precise regulatory mechanisms…”
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Aberrant Promoter Hypomethylation of Sortilin 1: A Moyamoya Disease Biomarker by Sung, Hye Youn, Lee, Ji Yeoun, Park, Ae Kyung, Moon, Youn Joo, Jo, Inho, Park, Eun-Mi, Wang, Kyu-Chang, Phi, Ji Hoon, Ahn, Jung-Hyuck, Kim, Seung-Ki

“…The pathogenesis of moyamoya disease (MMD) remains poorly understood, and no reliable molecular biomarkers for MMD have been identified to date. The present…”
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Anti-inflammatory and antioxidant mechanisms of urolithin B in activated microglia by Lee, Gyeongjin, Park, Jin-Sun, Lee, Eun-Jung, Ahn, Jung-Hyuck, Kim, Hee-Sun

“…Urolithin B is one of the gut microbial metabolites of ellagitannins and is found in diverse plant foods, including pomegranates, berries, walnuts, tropical…”
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