Search Results - "Ahn, Christopher S"

Metabolic Reprogramming of Stromal Fibroblasts through p62-mTORC1 Signaling Promotes Inflammation and Tumorigenesis by Valencia, Tania, Kim, Ji Young, Abu-Baker, Shadi, Moscat-Pardos, Jorge, Ahn, Christopher S., Reina-Campos, Miguel, Duran, Angeles, Castilla, Elias A., Metallo, Christian M., Diaz-Meco, Maria T., Moscat, Jorge

“…The tumor microenvironment plays a critical role in cancer progression, but the precise mechanisms by which stromal cells influence the epithelium are poorly…”
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Mitochondria as biosynthetic factories for cancer proliferation by Ahn, Christopher S, Metallo, Christian M

“…Unchecked growth and proliferation is a hallmark of cancer, and numerous oncogenic mutations reprogram cellular metabolism to fuel these processes. As a…”
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Combinatorial CRISPR-Cas9 Metabolic Screens Reveal Critical Redox Control Points Dependent on the KEAP1-NRF2 Regulatory Axis by Zhao, Dongxin, Badur, Mehmet G., Luebeck, Jens, Magaña, Jose H., Birmingham, Amanda, Sasik, Roman, Ahn, Christopher S., Ideker, Trey, Metallo, Christian M., Mali, Prashant

“…The metabolic pathways fueling tumor growth have been well characterized, but the specific impact of transforming events on network topology and enzyme…”
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ATF4-Induced Metabolic Reprograming Is a Synthetic Vulnerability of the p62-Deficient Tumor Stroma by Linares, Juan F., Cordes, Thekla, Duran, Angeles, Reina-Campos, Miguel, Valencia, Tania, Ahn, Christopher S., Castilla, Elias A., Moscat, Jorge, Metallo, Christian M., Diaz-Meco, Maria T.

“…Tumors undergo nutrient stress and need to reprogram their metabolism to survive. The stroma may play a critical role in this process by providing nutrients to…”
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Loss of myoferlin redirects breast cancer cell motility towards collective migration by Volakis, Leonithas I, Li, Ruth, Ackerman, 4th, William E, Mihai, Cosmin, Bechel, Meagan, Summerfield, Taryn L, Ahn, Christopher S, Powell, Heather M, Zielinski, Rachel, Rosol, Thomas J, Ghadiali, Samir N, Kniss, Douglas A

“…Cell migration plays a central role in the invasion and metastasis of tumors. As cells leave the primary tumor, they undergo an epithelial to mesenchymal…”
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Abstract SY01-02: Autophagy and metabolic reprogramming in the tumor stroma by Moscat, Jorge, Linares, Juan F., Duran, Angeles, Valencia, Tania, Ahn, Christopher S., Metallo, Christian, Diaz-Meco, Maria T.

“…Cancer is the result of the stepwise acquisition of genetic alterations within the epithelial compartment. However, recent data supports the relevance of the…”
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