Search Results - "Ahn, Brian"

Isocitrate dehydrogenase mutations suppress STAT1 and CD8+ T cell accumulation in gliomas by Kohanbash, Gary, Carrera, Diego A, Shrivastav, Shruti, Ahn, Brian J, Jahan, Naznin, Mazor, Tali, Chheda, Zinal S, Downey, Kira M, Watchmaker, Payal B, Beppler, Casey, Warta, Rolf, Amankulor, Nduka A, Herold-Mende, Christel, Costello, Joseph F, Okada, Hideho

“…Mutations in the isocitrate dehydrogenase genes IDH1 and IDH2 are among the first genetic alterations observed during the development of lower-grade glioma…”
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TGF-β downregulates the activating receptor NKG2D on NK cells and CD8+ T cells in glioma patients by Crane, Courtney A., Han, Seunggu J., Barry, Jeffery J., Ahn, Brian J., Lanier, Lewis L., Parsa, Andrew T.

“…The activating receptor NKG2D, expressed by natural killer (NK) cells and CD8+ T cells, has a role in the specific killing of transformed cells. We examined…”
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Induction of robust type-I CD8+ T-cell responses in WHO grade 2 low-grade glioma patients receiving peptide-based vaccines in combination with poly-ICLC by Okada, Hideho, Butterfield, Lisa H, Hamilton, Ronald L, Hoji, Aki, Sakaki, Masashi, Ahn, Brian J, Kohanbash, Gary, Drappatz, Jan, Engh, Johnathan, Amankulor, Nduka, Lively, Mark O, Chan, Michael D, Salazar, Andres M, Shaw, Edward G, Potter, Douglas M, Lieberman, Frank S

“…WHO grade 2 low-grade gliomas (LGG) with high risk factors for recurrence are mostly lethal despite current treatments. We conducted a phase I study to…”
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Soluble factors secreted by glioblastoma cell lines facilitate recruitment, survival, and expansion of regulatory T cells: implications for immunotherapy by Crane, Courtney A, Ahn, Brian J, Han, Seunggu J, Parsa, Andrew T

“…In patients with glioma, the tumor microenvironment can significantly impact pro-inflammatory immune cell functions. However, the mechanisms by which this…”
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Immune-checkpoint blockade and active immunotherapy for glioma by Ahn, Brian J, Pollack, Ian F, Okada, Hideho

“…Cancer immunotherapy has made tremendous progress, including promising results in patients with malignant gliomas. Nonetheless, the immunological…”
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A systematic review of intracranial chondrosarcoma and survival by Bloch, Orin G, Jian, Brian J, Yang, Isaac, Han, Seunggu J, Aranda, Derick, Ahn, Brian J, Parsa, Andrew T

“…Abstract Most data regarding survival in patients with chondrosarcoma are limited to case studies and small series performed at single institutions. A…”
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Clinical characteristics and outcomes for a modern series of primary gliosarcoma patients by Han, Seunggu J., Yang, Isaac, Ahn, Brian J., Otero, Jose J., Tihan, Tarik, McDermott, Michael W., Berger, Mitchel S., Prados, Michael D., Parsa, Andrew T.

“…BACKGROUND: Primary gliosarcoma (PGS) is a rare central nervous system tumor with limited experience reported in the literature. In the current study, the…”
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Effectiveness of the AAOS Leadership Fellows Program for Orthopaedic Surgeons by Day, Charles S., Tabrizi, Shervin, Kramer, Jeffrey, Yule, Arthur C., Ahn, Brian S.

“…Effective physician leadership is critical to the future success of healthcare organizations. The American Academy of Orthopaedic Surgeons (AAOS) Leadership…”
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Secondary gliosarcoma after diagnosis of glioblastoma: clinical experience with 30 consecutive patients by Han, Seunggu J, Yang, Isaac, Otero, Jose J, Ahn, Brian J, Tihan, Tarik, McDermott, Michael W, Berger, Mitchel S, Chang, Susan M, Parsa, Andrew T

“…Gliosarcoma can arise secondarily, after conventional adjuvant treatment of high-grade glioma. The current literature on the occurrence of secondary…”
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Histamine deficiency promotes accumulation of immunosuppressive immature myeloid cells and growth of murine gliomas by Ahn, Brian, Kohanbash, Gary, Ohkuri, Takayuki, Kosaka, Akemi, Chen, Xiaowei, Ikeura, Maki, Wang, Timothy C, Okada, Hideho

“…To elucidate mechanisms underlying epidemiological findings of decreased risk of glioma development in patients with allergies and asthma, gliomas were induced…”
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Gamma interferon-mediated superinduction of B7-H1 in PTEN-deficient glioblastoma: a paradoxical mechanism of immune evasion by Han, Seunggu J, Ahn, Brian J, Waldron, James S, Yang, Isaac, Fang, Shanna, Crane, Courtney A, Pieper, Russell O, Parsa, Andrew T

“…B7 homolog 1 (B7-H1) is a recently discovered immunoresistance protein that is regulated posttranscriptionally after PTEN loss in malignant glioma, a deadly…”
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Secondary gliosarcoma after diagnosis of glioblastoma: clinical experience with 30 consecutive patients: Clinical article by HAN, Seunggu J, YANG, Isaac, OTERO, Jose J, AHN, Brian J, TIHAN, Tarik, MCDERMOTT, Michael W, BERGER, Mitchel S, CHANG, Susan M, PARSA, Andrew T

“…Object Gliosarcoma can arise secondarily, after conventional adjuvant treatment of high-grade glioma. The current literature on the occurrence of secondary…”
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complement cascade as a mediator of tissue growth and regeneration by Rutkowski, Martin J, Sughrue, Michael E, Kane, Ari J, Ahn, Brian J, Fang, Shanna, Parsa, Andrew T

“…Recent evidence has demonstrated that the complement cascade is involved in a variety of physiologic and pathophysiologic processes in addition to its role as…”
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ROBUST INDUCTION OF TYPE-1 CD8+ T-CELL RESPONSES IN WHO GRADE II LOW-GRADE GLIOMA PATIENTS RECEIVING PEPTIDE-BASED VACCINES IN COMBINATION WITH POLY-ICLC by Okada, H., Butterfield, L. H., Hamilton, R. L., Hoji, A., Sakaki, M., Ahn, B. J., Kohanbash, G., Drappatz, J., Engh, J., Amankulor, N., Lively, M. O., Chan, M. D., Salazar, A. M., Potter, D. M., Shaw, E. G., Lieberman, F. S.

“…BACKGROUND: WHO grade II low-grade gliomas (LGGs) with high risk factors for recurrence are mostly lethal despite current treatments, and novel approaches are…”
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Hand and Wrist Research Productivity: A Twenty-year Analysis by Ahn, Christine, BA, Li, Richard, BA, Ahn, Brian, BA, Kuo, Phoebe, Day, Charles S., MD

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Changes in Brain-derived Neurotrophic Factor From Active and Sham Transcranial Direct Current Stimulation in Older Adults With Knee Osteoarthritis by Suchting, Robert, Teixeira, Antonio L., Ahn, Brian, Colpo, Gabriela D., Park, Juyoung, Ahn, Hyochol

“…Objectives: Previous work has shown effects of transcranial direct current stimulation (tDCS) on clinical pain measures, qualitative sensory testing measures,…”
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Cranial chondrosarcoma and recurrence by Bloch, Orin G, Jian, Brian J, Yang, Isaac, Han, Seunggu J, Aranda, Derick, Ahn, Brian J, Parsa, Andrew T

“…The literature regarding recurrences in patients with cranial chondrosarcoma is limited to small series performed at single institutions, raising the question…”
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Individual Patient-Specific Immunity against High-Grade Glioma after Vaccination with Autologous Tumor Derived Peptides Bound to the 96 KD Chaperone Protein by CRANE, Courtney A, HAN, Seunggu J, MCDERMOTT, Michael W, PRADOS, Michael D, PARSA, Andrew T, AHN, Brian, OEHLKE, Jessica, KIVETT, Valerie, FEDOROFF, Anne, BUTOWSKI, Nicholas, CHANG, Susan M, CLARKE, Jennifer, BERGER, Mitchel S

“…Cancer immunotherapy offers hope of a highly specific nontoxic adjuvant treatment. Heat shock protein peptide complexes (HSPPCs) found in cancer cells carry…”
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Transcranial Direct Current Stimulation in Nicotine Use: Nursing Implications for Patient Outcomes by Gwon, Seok Hyun, Lee, Han-Joo, Brian Ahn, Hyochol

“…Abstract Tobacco use is a leading cause of cancer, cardiovascular and respiratory disease, and preventable death in the United States. The brains of…”
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Increased Alternative Complement Pathway Function and Improved Survival during Critical Illness by Bain, William, Li, Huihua, van der Geest, Rick, Moore, Sara R, Olonisakin, Tolani F, Ahn, Brian, Papke, Erin, Moghbeli, Kaveh, DeSensi, Rebecca, Rapport, Sarah, Saul, Melissa, Hulver, Mei, Xiong, Zeyu, Mallampalli, Rama K, Ray, Prabir, Morris, Alison, Ma, Lina, Doi, Yohei, Zhang, Yingze, Kitsios, Georgios D, Kulkarni, Hrishikesh S, McVerry, Bryan J, Ferreira, Viviana P, Nouraie, Mehdi, Lee, Janet S

“…Complement is crucial for host defense but may also drive dysregulated inflammation. There is limited understanding of alternative complement function, which…”
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