Search Results - "Ahmed Safwat"

Anti-Helicobacter, Antitubercular and Cytotoxic Activities of Scalaranes from the Red Sea Sponge Hyrtios erectus by Alahdal, Abdulrahman M, Asfour, Hani Z, Ahmed, Safwat A, Noor, Ahmad O, Al-Abd, Ahmed M, Elfaky, Mahmoud A, Elhady, Sameh S

“…The Red Sea specimen of the marine sponge (order Dictyoceratida) was found to contain scalarane-type sesterterpenes. 12- -deacetyl-12,19-di- -scalarin ( ), a…”
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The effect of fusion sputtering surface treatment on microshear bond strength of zirconia and MDP-containing resin cement by Ali, Nesma, Safwat, Ahmed, Aboushelib, Moustafa

“…The aim of this study is to evaluate the effect of fusion sputtering surface treatment on the microshear bond strength of zirconia and self-adhesive…”
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Editorial Comment from Dr Safwat to Risk of urinary stones among women with pelvic organ prolapse: A national population‐based cohort study by Safwat, Ahmed S

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Minor oxygenated cannabinoids from high potency Cannabis sativa L by Ahmed, Safwat A., Ross, Samir A., Slade, Desmond, Radwan, Mohamed M., Khan, Ikhlas A., ElSohly, Mahmoud A.

“…Nine oxygenated cannabinoids (1–9) were isolated from a high potency Cannabis sativa L. variety. Their chemical structures were elucidated using spectroscopic…”
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The long-term consequences of the hypospadias salvage repair issue by Hammouda, Hisham M, Shahat, Ahmed A, Safwat, Ahmed S, Taha, Taha M

“…To present the long-term results of redo-hypospadias at our tertiary referral center following a failed prior repair. One hundred sixty-four individuals with a…”
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Editorial Comment to Two‐year‐old girl with impacted ureteral stone successfully treated with a single session of combined percutaneous nephrostomy and ureteroscopy by Safwat, Ahmed S

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Antiproliferative Scalarane-Based Metabolites from the Red Sea Sponge Hyrtios erectus by Elhady, Sameh S, Al-Abd, Ahmed M, El-Halawany, Ali M, Alahdal, Abdulrahman M, Hassanean, Hashim A, Ahmed, Safwat A

“…Two new sesterterpenes analogs, namely, 12-acetoxy,16-epi-hyrtiolide (1) and 12β-acetoxy,16β-methoxy,20α-hydroxy-17-scalaren-19,20-olide (2), containing a…”
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Isolation and Pharmacological Evaluation of Minor Cannabinoids from High-Potency Cannabis sativa by Radwan, Mohamed M, ElSohly, Mahmoud A, El-Alfy, Abir T, Ahmed, Safwat A, Slade, Desmond, Husni, Afeef S, Manly, Susan P, Wilson, Lisa, Seale, Suzanne, Cutler, Stephen J, Ross, Samir A

“…Seven new naturally occurring hydroxylated cannabinoids (1–7), along with the known cannabiripsol (8), have been isolated from the aerial parts of high-potency…”
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Evaluation of 2-Thioxoimadazolidin-4-one Derivatives as Potent Anti-Cancer Agents through Apoptosis Induction and Antioxidant Activation: In Vitro and In Vivo Approaches by Nafie, Mohamed S, Khodair, Ahmed I, Hassan, Hebat Allah Y, El-Fadeal, Noha M Abd, Bogari, Hanin A, Elhady, Sameh S, Ahmed, Safwat A

“…Hepatocellular carcinoma (HCC) is one of the most widespread malignancies and is reported as the fourth most prevalent cause of cancer deaths worldwide…”
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A New Bioactive Metabolite Isolated from the Red Sea Marine Sponge Hyrtios erectus by Elhady, Sameh S, El-Halawany, Ali M, Alahdal, Abdulrahman M, Hassanean, Hashim A, Ahmed, Safwat A

“…Chemical investigation of the lipophilic fraction of Hyrtios erectus, a Red Sea sponge, yielded a new pentacyclic nitrogen-containing scalarane;…”
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Dual SARS-CoV-2 and MERS-CoV inhibitors from Artemisia monosperma : isolation, structure elucidation, molecular modelling studies, and in vitro activities by Badawy, Ahmed M, Donia, Marwa Samir M, Hamdy, Nehal G, El-Ayouty, Mayada M, Mohamed, Osama G, Darwish, Khaled M, Tripathi, Ashootosh, Ahmed, Safwat A

“…The COVID-19 pandemic has spread throughout the whole globe, so it is imperative that all available resources be used to treat this scourge. In reality, the…”
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Dereplication strategies for targeted isolation of new antitrypanosomal actinosporins A and B from a marine sponge associated-Actinokineospora sp. EG49 by Abdelmohsen, Usama Ramadan, Cheng, Cheng, Viegelmann, Christina, Zhang, Tong, Grkovic, Tanja, Ahmed, Safwat, Quinn, Ronald J, Hentschel, Ute, Edrada-Ebel, RuAngelie

“…High resolution Fourier transform mass spectrometry (HRFTMS) and nuclear magnetic resonance (NMR) spectroscopy were employed as complementary metabolomic tools…”
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Molecular Docking and Dynamics Simulation Study of Hyrtios erectus Isolated Scalarane Sesterterpenes as Potential SARS-CoV-2 Dual Target Inhibitors by Elhady, Sameh S., Abdelhameed, Reda F. A., Malatani, Rania T., Alahdal, Abdulrahman M., Bogari, Hanin A., Almalki, Ahmad J., Mohammad, Khadijah A., Ahmed, Safwat A., Khedr, Amgad I. M., Darwish, Khaled M.

“…Presently, the world is under the toll of pandemic coronavirus disease-2019 (COVID-19) outbreak caused by SARS-CoV-2. Lack of effective and safe therapeutics…”
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New antibacterial xanthone from the marine sponge-derived Micrococcus sp. EG45 by Eltamany, Enas E., Abdelmohsen, Usama Ramadan, Ibrahim, Amany K., Hassanean, Hashim A., Hentschel, Ute, Ahmed, Safwat A.

“…[Display omitted] Microluside A [4 (19-para-hydroxy benzoyloxy-O-β-d-cellobiosyl), 5 (30-para-hydroxy benzoyloxy-O-β-d-glucopyranosyl) xanthone (1)] is a…”
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Zygo-Albuside A: New Saponin from Zygophyllum album L. with Significant Antioxidant, Anti-Inflammatory and Antiapoptotic Effects against Methotrexate-Induced Testicular Damage by Abdelhameed, Reda F. A., Fattah, Shaimaa A., Mehanna, Eman T., Hal, Dina M., Mosaad, Sarah M., Abdel-Kader, Maged S., Ibrahim, Amany K., Ahmed, Safwat A., Badr, Jihan M., Eltamany, Enas E.

“…Chemical investigation of the crude extract of the aerial part of Zygophyllum album L. (Z. album) led to the isolation of a new saponin, Zygo-albuside A (7),…”
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A new antitrypanosomal alkaloid from the Red Sea marine sponge Hyrtios sp by Shady, Nourhan Hisham, Fouad, Mostafa A., Ahmed, Safwat, Pimentel-Elardo, Sheila Marie, Nodwell, Justin R., Kamel, Mohamed Salah, Abdelmohsen, Usama Ramadan

“…The antitrypanosomally active crude extract of the sponge Hyrtios sp. was subjected to metabolomic analysis using liquid chromatography coupled with high…”
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Chemical Constituent Profiling of Phyllostachys heterocycla var. Pubescens with Selective Cytotoxic Polar Fraction through EGFR Inhibition in HepG2 Cells by Abdelhameed, Reda F A, Habib, Eman S, Ibrahim, Ahmed K, Yamada, Koji, Abdel-Kader, Maged S, Ahmed, Safwat A, Ibrahim, Amany K, Badr, Jihan M, Nafie, Mohamed S

“…Different extracts of the Bamboo shoot skin var. pubescens were screened against panel of cancer cell lines and normal one. The cell viability results…”
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In vivo determination of analgesic and anti-inflammatory activities of isolated compounds from Cleome amblyocarpa and molecular modelling for the top active investigated compounds by El-Ayouty, Mayada M, Eltahawy, Nermeen A, Abd El-Sameaa, Ahmed M, Badawy, Ahmed M, Darwish, Khaled M, Elhady, Sameh S, Shokr, Mostafa M, Ahmed, Safwat A

“…Barr. and Murb. from the family Cleomaceae is used in folk medicine as it has analgesic, anti-inflammatory, antibacterial and antioxidant activities. In this…”
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Isolated compounds from Cuscuta pedicellata ameliorate oxidative stress and upregulate expression of some energy regulatory genes in high fat diet induced obesity in rats by Mehanna, Eman T., El-sayed, Norhan M., Ibrahim, Amany K., Ahmed, Safwat A., Abo-Elmatty, Dina M.

“…[Display omitted] •The study involved the extract of C. pedicellata and ten of its isolated compounds.•The investigated compounds showed anti-oxidant effect in…”
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Biologically Active Cannabinoids from High-Potency Cannabis sativa by Radwan, Mohamed M, ElSohly, Mahmoud A, Slade, Desmond, Ahmed, Safwat A, Khan, Ikhlas A, Ross, Samir A

“…Nine new cannabinoids (1−9) were isolated from a high-potency variety of Cannabis sativa. Their structures were identified as (±)-4-acetoxycannabichromene (1),…”
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