Search Results - "Ahmed Abdi, Bahja"

Pathogenic Activation of Mesenchymal Stem Cells Is Induced by the Disease Microenvironment in Systemic Sclerosis by Taki, Zeinab, Gostjeva, Elena, Thilly, William, Yaseen, Bodoor, Lopez, Henry, Mirza, Maria, Hassuji, Zainab, Vigneswaran, Shivanee, Ahmed Abdi, Bahja, Hart, Amy, Arumalla, Nikita, Thomas, Gemma, Denton, Christopher P., Suleman, Yasir, Liu, Huan, Venturini, Cristina, O'Reilly, Steven, Xu, Shiwen, Stratton, Richard

“…Objective In systemic sclerosis (SSc), a persistent tissue repair process leads to progressive fibrosis of the skin and internal organs. The role of…”
Get full text

Use of Patterned Collagen Coated Slides to Study Normal and Scleroderma Lung Fibroblast Migration by Ahmed Abdi, Bahja, Lopez, Henry, Karrar, Sarah, Renzoni, Elisabetta, Wells, Athol, Tam, Angela, Etomi, Oseme, Hsuan, J. Justin, Martin, George R., Shiwen, Xu, Denton, Christopher P., Abraham, David, Stratton, Richard

“…Systemic sclerosis (SSc) is a spreading fibrotic disease affecting the skin and internal organs. We aimed to model pathogenic fibroblast migration in SSc in…”
Get full text

200 Evaluating novel peptide therapeutics targeting pathogenic macrophages in systemic sclerosis by Stanway, James, Abdi, Bahja Ahmed, Lopez, Henry, Martin, George, Stratton, Richard J

Get full text

A Role of Myocardin Related Transcription Factor-A (MRTF-A) in Scleroderma Related Fibrosis by Shiwen, Xu, Stratton, Richard, Nikitorowicz-Buniak, Joanna, Ahmed-Abdi, Bahja, Ponticos, Markella, Denton, Christopher, Abraham, David, Takahashi, Ayuko, Suki, Bela, Layne, Matthew D, Lafyatis, Robert, Smith, Barbara D

“…In scleroderma (systemic sclerosis, SSc), persistent activation of myofibroblast leads to severe skin and organ fibrosis resistant to therapy. Increased…”
Get full text

Interleukin-31 promotes pathogenic mechanisms underlying skin and lung fibrosis in scleroderma by Yaseen, Bodoor, Lopez, Henry, Taki, Zeinab, Zafar, Sara, Rosario, Henrique, Abdi, Bahja Ahmed, Vigneswaran, Shivanee, Xing, Fiona, Arumalla, Nikita, Black, Simon, Ahmad, Sara, Kumar, Kimti, Gul, Rabia, Scolamiero, Laura, Morris, Sian, Bowman, Alex, Stainer, Anna, Rice, Alexandra, Stock, Carmel, Renzoni, Elisabetta, Denton, Christopher P, Venturini, Cristina, Brown, Max, O’Reilly, Steven, Stratton, Richard

“…Abstract Objectives Cytokines released by infiltrating T cells may promote mechanisms leading to fibrosis in scleroderma. The aim of this study was to…”
Get full text

198 Critical role of the prolyl 3-hydroxylase LEPREL1 in scleroderma-related fibrosis by Ahmed, Bahja Abdi, Shiwen, Xu, Denton, Christopher, Martin, George, Fraser, Jess, Lopez, Henry, Stratton, Richard

Get full text

O17 Interleukin 31 promotes pathogenic mechanisms in scleroderma and induces skin fibrosis in mice by Arumalla, Nikita, Rosario, Henrique, Taki, Zeinab, Vigneswaran, Shivanee, Denton, Christopher, Abdi, Bahja Ahmed, Lopez, Henry, Stratton, Richard

Get full text

193 Correlating plasma cytokine levels with right heart catheterisation parameters in systemic sclerosis-related pulmonary arterial hypertension by Ho, Chup Hei, Nihtyanova, Svetlana, Abdi, Bahja Ahmed, Coghlan, Gerry, Denton, Christopher, Schreiber, Benjamin, Ong, Voon Hong

Get full text

Autoantibodies Which Bind to and Activate Keratinocytes in Systemic Sclerosis by Moezinia, Carine, Wong, Valerie, Watson, James, Nagib, Lydia, Lopez Garces, Sandra, Zhang, Siyu, Ahmed Abdi, Bahja, Newton, Florence, Abraham, David, Stratton, Richard

“…Systemic sclerosis (SSc) is a multisystem connective tissue disease characterised by pathological processes involving autoimmunity, vasculopathy and resultant…”
Get full text

Multiplex cytokine analysis of dermal interstitial blister fluid defines local disease mechanisms in systemic sclerosis by Clark, Kristina En, Lopez, Henry, Abdi, Bahja Ahmed, Guerra, Sandra G, Shiwen, Xu, Khan, Korsa, Etomi, Oseme, Martin, George R, Abraham, David J, Denton, Christopher P, Stratton, Richard J

“…Clinical diversity in systemic sclerosis (SSc) reflects multifaceted pathogenesis and the effect of key growth factors or cytokines operating within a…”
Get full text

P247 Novel therapeutic peptides targeting CD206 modulate ATP-induced release of inflammatory and B cell activating factors in lupus macrophages by Shah, Shivanee, Smillie, Robert, Abdi, Bahja Ahmed, Stratton, Richard J

Get full text

P140 IgG Autoantibodies with Increased Affinity for Epithelial Cells in Severe Systemic Sclerosis by Moezinia, Carine, Wong, Valerie, Watson, James, Nagib, Lydia, Garces, Sandra Lopez, Lopez, Henry, Martin, George, Zhang, Siyu, Abdi, Bahja Ahmed, Denton, Christopher, Abraham, David, Stratton, Richard J

Get full text

P147 M2 macrophage associated fibrosis in early stage systemic sclerosis: an update on plasma biomarkers by Leeves, Laura A, Kannan, Zestranjyan, Ali, Yunus, Pan, Liyang, Malley, Tamir, Abraham, David, Leask, Andrew, Riser, Bruce, Abdi, Bahja Ahmed, Stratton, Richard J

Get full text

P231 Targeting the Rho/MRTF-A pathway inhibits growth factor and cytokine release but enhances efferocytosis in scleroderma macrophages by Garces, Sandra Lopez, Abdi, Bahja Ahmed, MacFadyen, Claire, Smillie, Robert, Nagib, Lydia, Ghani, Shahi, Shah, Shivani, Abraham, David, Denton, Christopher, Stratton, Richard J

Get full text

Randomised single centre double-blind placebo controlled phase II trial of Tocovid SupraBio in combination with pentoxifylline in patients suffering long-term gastrointestinal adverse effects of radiotherapy for pelvic cancer: The PPALM study by Andreyev, H. Jervoise N., Matthews, Jennifer, Adams, Carolyn, Gothard, Lone, Lucy, Claire, Tovey, Holly, Boyle, Sue, Anbalagan, Selvakumar, Musallam, Annette, Yarnold, John, Abraham, David, Bliss, Judith, Abdi, Bahja Ahmed, Taylor, Alexandra, Hauer-Jensen, Martin

“…•First human trial of gamma-tocotrienol with pentoxifylline assessing its potential to reduce radiotherapy-induced gastrointestinal damage .•Change in…”
Get full text

O06 Prolyl 3-hydroxylase 2 is a candidate gene in scleroderma involved in collagen synthesis and fibrosis by Abdi, Bahja Ahmed, Shiwen, Xu, Arumalla, Nikita, Denton, Christopher, Abraham, David, Stratton, Richard

Get full text

P155 Modelling calcinosis in systemic sclerosis through disease microenvironment-stem cell interactions: effect of novel therapeutic peptide RP832c by Coumbe, Ben G T, Ahmad, Sonia N, Thomas, Gemma, Borukhson, Liubov, Abdi, Bahja Ahmed, Lopez, Henry, Garvin, Charles, Jaynes, Jesse, Yates, Clayton, Martin, George, Denton, Christopher, Abraham, David, Stratton, Richard J

“…Background/Aims  Systemic sclerosis (SSc) is a rare and progressive connective tissue disease that is more common in women in the third to fifth decades of…”
Get full text

252Investigating the Misfolded Protein Response in Systemic Sclerosis by Delaney, Matthew, Ahmed Abdi, Bahja, Denton, Christopher, Abraham, David, Arumalla, Nikita, Gibson, Mark, Stratton, Richard

Get full text

256Investigating the Role of a C-Kit-Positive Subpopulation in Scleroderma Lung Fibroblasts by Ahmed Abdi, Bahja, Etomi, Oseme, Lopez, Henry, Abraham, David, Denton, Christopher, Stratton, Richard

Get full text

307. MACROPHAGES FROM A SCLERODERMA SUBGROUP WITH HIGHER SKIN SCORES EXPRESS ACTIVATION MARKERS AND INDUCE FIBROBLASTS IN CO-CULTURE by King, Jamie, Sleep, David, Sohrabi, Yassmin, Tam, Angela, Abdi, Bahja Ahmed, Abraham, David, Denton, Christopher, Stratton, Richard

Get full text