Search Results - "Ahmed, Syed F"

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  1. 1

    Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain by Magnussen, Helge M., Ahmed, Syed F., Sibbet, Gary. J., Hristova, Ventzislava A., Nomura, Koji, Hock, Andreas K., Archibald, Lewis J., Jamieson, Andrew G., Fushman, David, Vousden, Karen H., Weissman, Allan M., Huang, Danny T.

    Published in Nature communications (29-04-2020)
    “…Phosphorylation of MDM2 by ATM upon DNA damage is an important mechanism for deregulating MDM2, thereby leading to p53 activation. ATM phosphorylates multiple…”
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    Journal Article
  2. 2

    DTX3L ubiquitin ligase ubiquitinates single-stranded nucleic acids by Dearlove, Emily L, Chatrin, Chatrin, Buetow, Lori, Ahmed, Syed F, Schmidt, Tobias, Bushell, Martin, Smith, Brian O, Huang, Danny T

    Published in eLife (08-10-2024)
    “…Ubiquitination typically involves covalent linking of ubiquitin (Ub) to a lysine residue on a protein substrate. Recently, new facets of this process have…”
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    Journal Article
  3. 3

    A comparison of the bone and growth phenotype of mdx , mdx:Cmah -/- and mdx:Utrn +/- murine models with the C57BL/10 wild-type mouse by Wood, Claire L, Suchacki, Karla J, van 't Hof, Rob, Cawthorn, Will P, Dillon, Scott, Straub, Volker, Wong, Sze Choong, Ahmed, Syed F, Farquharson, Colin

    Published in Disease models & mechanisms (01-02-2020)
    “…The muscular dystrophy X-linked ( ) mouse is commonly used as a mouse model of Duchenne muscular dystrophy (DMD). Its phenotype is, however, mild, and other…”
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    Journal Article
  4. 4

    Structural insights into ADP-ribosylation of ubiquitin by Deltex family E3 ubiquitin ligases by Chatrin, Chatrin, Gabrielsen, Mads, Buetow, Lori, Nakasone, Mark A, Ahmed, Syed F, Sumpton, David, Sibbet, Gary J, Smith, Brian O, Huang, Danny T

    Published in Science advances (01-09-2020)
    “…Cellular cross-talk between ubiquitination and other posttranslational modifications contributes to the regulation of numerous processes. One example is…”
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    Journal Article
  5. 5

    Increased linear bone growth by GH in the absence of SOCS2 is independent of IGF-1 by Dobie, Ross, Ahmed, Syed F., Staines, Katherine A., Pass, Chloe, Jasim, Seema, MacRae, Vicky E., Farquharson, Colin

    Published in Journal of cellular physiology (01-11-2015)
    “…Growth hormone (GH) signaling is essential for postnatal linear bone growth, but the relative importance of GHs actions on the liver and/or growth plate…”
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    Journal Article
  6. 6

    Assessment of toxicities and outcomes in patients with breast cancer treated with hypofractionated radiotherapy by Sindhu, M, Malik, Monica, Ahmed, Syed, Valiyaveettil, Deepthi

    Published in Indian journal of cancer (01-10-2020)
    “…Background: Hypofractionation is now becoming the standard of care in breast irradiation. The aim of this study was to assess the toxicities and outcomes in…”
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    Journal Article
  7. 7

    Histological Assessment of Gonads in DSD: Relevance for Clinical Management by Spoor, Johannes A, Oosterhuis, J Wolter, Hersmus, Remko, Biermann, Katharina, Wolffenbuttel, Katja P, Cools, Martine, Kazmi, Zainab, Ahmed, Syed F, Looijenga, Leendert H J

    Published in Sexual development (01-02-2018)
    “…Malignant gonadal germ cell tumors, referred to as germ cell cancers (GCC), occur with increased frequency in individuals who have specific types of…”
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    Journal Article
  8. 8
  9. 9

    DTX3L ubiquitin ligase ubiquitinates single-stranded nucleic acids by Dearlove, Emily L, Chatrin, Chatrin, Buetow, Lori, Ahmed, Syed F, Schmidt, Tobias, Bushell, Martin, Smith, Brian O, Huang, Danny T

    Published in eLife (08-10-2024)
    “…Ubiquitination typically involves covalent linking of ubiquitin (Ub) to a lysine residue on a protein substrate. Recently, new facets of this process have…”
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    Journal Article
  10. 10

    Autoinflammation in patients with leukocytic CBL loss of heterozygosity is caused by constitutive ERK-mediated monocyte activation by Bohlen, Jonathan, Bagarić, Ivan, Vatovec, Taja, Ogishi, Masato, Ahmed, Syed F, Cederholm, Axel, Buetow, Lori, Sobrino, Steicy, Le Floc'h, Corentin, Arango-Franco, Carlos A, Seabra, Luis, Michelet, Marine, Barzaghi, Federica, Leardini, Davide, Saettini, Francesco, Vendemini, Francesca, Baccelli, Francesco, Catala, Albert, Gambineri, Eleonora, Veltroni, Marinella, Aguilar de la Red, Yurena, Rice, Gillian I, Consonni, Filippo, Berteloot, Laureline, Largeaud, Laetitia, Conti, Francesca, Roullion, Cécile, Masson, Cécile, Bessot, Boris, Seeleuthner, Yoann, Le Voyer, Tom, Rinchai, Darawan, Rosain, Jérémie, Neehus, Anna-Lena, Erazo-Borrás, Lucia, Li, Hailun, Janda, Zarah, Cho, En-Jui, Muratore, Edoardo, Soudée, Camille, Lainé, Candice, Delabesse, Eric, Goulvestre, Claire, Ma, Cindy S, Puel, Anne, Tangye, Stuart G, André, Isabelle, Bole-Feysot, Christine, Abel, Laurent, Erlacher, Miriam, Zhang, Shen-Ying, Béziat, Vivien, Lagresle-Peyrou, Chantal, Six, Emmanuelle, Pasquet, Marlène, Alsina, Laia, Aiuti, Alessandro, Zhang, Peng, Crow, Yanick J, Landegren, Nils, Masetti, Riccardo, Huang, Danny T, Casanova, Jean-Laurent, Bustamante, Jacinta

    Published in The Journal of clinical investigation (15-10-2024)
    “…Patients heterozygous for germline CBL loss-of-function (LOF) variants can develop myeloid malignancy, autoinflammation, or both, if some or all of their…”
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    Journal Article
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  13. 13

    Fetal effects of cocaine: an updated meta-analysis by Addis, Antonio, Moretti, Myla E., Ahmed Syed, Fayyazuddin, Einarson, Thomas R., Koren, Gideon

    Published in Reproductive toxicology (Elmsford, N.Y.) (01-07-2001)
    “…Background: A very large number of women in the reproductive age group consume cocaine, leading to grave concerns regarding the long term health of millions of…”
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    Journal Article Conference Proceeding
  14. 14

    Reproducibility of medical information obtained via the telephone vs personal interview by Einarson, A, Ahmed Syed, F, Gallo, M, Einarson, T R, Koren, G, Ahmed, F

    Published in Veterinary and human toxicology (01-12-1999)
    “…The Motherisk [corrected] Program, a teratogenic information service, conducts patient interviews over the telephone as well as in a clinic setting. In both…”
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    Journal Article