Search Results - "Ahmed, Syed F"
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Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain
Published in Nature communications (29-04-2020)“…Phosphorylation of MDM2 by ATM upon DNA damage is an important mechanism for deregulating MDM2, thereby leading to p53 activation. ATM phosphorylates multiple…”
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DTX3L ubiquitin ligase ubiquitinates single-stranded nucleic acids
Published in eLife (08-10-2024)“…Ubiquitination typically involves covalent linking of ubiquitin (Ub) to a lysine residue on a protein substrate. Recently, new facets of this process have…”
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A comparison of the bone and growth phenotype of mdx , mdx:Cmah -/- and mdx:Utrn +/- murine models with the C57BL/10 wild-type mouse
Published in Disease models & mechanisms (01-02-2020)“…The muscular dystrophy X-linked ( ) mouse is commonly used as a mouse model of Duchenne muscular dystrophy (DMD). Its phenotype is, however, mild, and other…”
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Structural insights into ADP-ribosylation of ubiquitin by Deltex family E3 ubiquitin ligases
Published in Science advances (01-09-2020)“…Cellular cross-talk between ubiquitination and other posttranslational modifications contributes to the regulation of numerous processes. One example is…”
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Increased linear bone growth by GH in the absence of SOCS2 is independent of IGF-1
Published in Journal of cellular physiology (01-11-2015)“…Growth hormone (GH) signaling is essential for postnatal linear bone growth, but the relative importance of GHs actions on the liver and/or growth plate…”
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Assessment of toxicities and outcomes in patients with breast cancer treated with hypofractionated radiotherapy
Published in Indian journal of cancer (01-10-2020)“…Background: Hypofractionation is now becoming the standard of care in breast irradiation. The aim of this study was to assess the toxicities and outcomes in…”
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Histological Assessment of Gonads in DSD: Relevance for Clinical Management
Published in Sexual development (01-02-2018)“…Malignant gonadal germ cell tumors, referred to as germ cell cancers (GCC), occur with increased frequency in individuals who have specific types of…”
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A child with congenital short gut associated with DYNC2LI1 ciliopathy
Published in Clinical dysmorphology (01-01-2021)Get full text
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DTX3L ubiquitin ligase ubiquitinates single-stranded nucleic acids
Published in eLife (08-10-2024)“…Ubiquitination typically involves covalent linking of ubiquitin (Ub) to a lysine residue on a protein substrate. Recently, new facets of this process have…”
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Autoinflammation in patients with leukocytic CBL loss of heterozygosity is caused by constitutive ERK-mediated monocyte activation
Published in The Journal of clinical investigation (15-10-2024)“…Patients heterozygous for germline CBL loss-of-function (LOF) variants can develop myeloid malignancy, autoinflammation, or both, if some or all of their…”
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The Physiology and Mechanism of Growth
Published in World review of nutrition and dietetics (01-01-2016)Get more information
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Fetal effects of cocaine: an updated meta-analysis
Published in Reproductive toxicology (Elmsford, N.Y.) (01-07-2001)“…Background: A very large number of women in the reproductive age group consume cocaine, leading to grave concerns regarding the long term health of millions of…”
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Reproducibility of medical information obtained via the telephone vs personal interview
Published in Veterinary and human toxicology (01-12-1999)“…The Motherisk [corrected] Program, a teratogenic information service, conducts patient interviews over the telephone as well as in a clinic setting. In both…”
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