Search Results - "Ahmed, Sharif U"
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Phage-Based Profiling of Rare Single Cells Using Nanoparticle-Directed Capture
Published in ACS nano (28-12-2021)“…Advances in single-cell level profiling of the proteome require quantitative and versatile platforms, especially for rare cell analyses such as circulating…”
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A magneto-activated nanoscale cytometry platform for molecular profiling of small extracellular vesicles
Published in Nature communications (11-09-2023)“…Exosomal PD-L1 (exoPD-L1) has recently received significant attention as a biomarker predicting immunotherapeutic responses involving the PD1/PD-L1 pathway…”
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Multifunctional 3D-Printed Wound Dressings
Published in ACS nano (27-07-2021)“…Personalized wound dressings provide enhanced healing for different wound types; however multicomponent wound dressings with discretely controllable delivery…”
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Single-cell mRNA cytometry via sequence-specific nanoparticle clustering and trapping
Published in Nature chemistry (01-05-2018)“…Cell-to-cell variation in gene expression creates a need for techniques that can characterize expression at the level of individual cells. This is particularly…”
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Nanostructured Architectures Promote the Mesenchymal–Epithelial Transition for Invasive Cells
Published in ACS nano (26-05-2020)“…Dynamic modulation of cellular phenotypes between the epithelial and mesenchymal statesthe epithelial–mesenchymal transition (EMT) and mesenchymal–epithelial…”
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Fluorescent Droplet Cytometry for On-Cell Phenotype Tracking
Published in Journal of the American Chemical Society (02-09-2020)“…Profiling the heterogeneous phenotypes of live cancer cells is a key capability that requires single-cell analysis. However, acquiring information at the…”
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Prismatic Deflection of Live Tumor Cells and Cell Clusters
Published in ACS nano (26-12-2018)“…The analysis of heterogeneous subpopulations of circulating tumor cells (CTCs) is critical to enhance our understanding of cancer metastasis and enable…”
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Tracking the expression of therapeutic protein targets in rare cells by antibody-mediated nanoparticle labelling and magnetic sorting
Published in Nature biomedical engineering (01-01-2021)“…Molecular-level features of tumours can be tracked using single-cell analyses of circulating tumour cells (CTCs). However, single-cell measurements of protein…”
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A putative vacuolar cargo receptor partially colocalizes with AtPEP12p on a prevacuolar compartment in Arabidopsis roots
Published in Proceedings of the National Academy of Sciences - PNAS (18-08-1998)“…Targeting of protein cargo to the vacuole/lysosome is a multistep process that appears to have conserved features between mammalian, yeast, and plant cells. In…”
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Isolation of Phenotypically Distinct Cancer Cells Using Nanoparticle-Mediated Sorting
Published in ACS applied materials & interfaces (21-06-2017)“…Isolating subpopulations of heterogeneous cancer cells is an important capability for the meaningful characterization of circulating tumor cells at different…”
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Aptamer and Antisense-Mediated Two-Dimensional Isolation of Specific Cancer Cell Subpopulations
Published in Journal of the American Chemical Society (02-03-2016)“…Cancer cells, and in particular those found circulating in blood, can have widely varying phenotypes and molecular profiles despite a common origin. New…”
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Ultrasensitive and rapid quantification of rare tumorigenic stem cells in hPSC-derived cardiomyocyte populations
Published in Science advances (01-03-2020)“…The ability to detect rare human pluripotent stem cells (hPSCs) in differentiated populations is critical for safeguarding the clinical translation of cell…”
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Toll-like receptor 4 mediates the antitumor host response induced by a 55-kilodalton protein isolated from Aeginetia indica L., a parasitic plant
Published in Clinical and diagnostic laboratory immunology (01-05-2004)“…A 55-kDa protein named AILb-A, isolated from the seed extract of Aeginetia indica L., a parasitic plant, induces a Th1-type T-cell response and elicits a…”
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Generation of subcutaneous and intrahepatic human hepatocellular carcinoma xenografts in immunodeficient mice
Published in Journal of visualized experiments (25-09-2013)“…In vivo experimental models of hepatocellular carcinoma (HCC) that recapitulate the human disease provide a valuable platform for research into disease…”
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The Plant Vacuolar Sorting Receptor AtELP Is Involved in Transport of NH2-Terminal Propeptide-Containing Vacuolar Proteins in Arabidopsis thaliana
Published in The Journal of cell biology (26-06-2000)“…Many soluble plant vacuolar proteins are sorted away from secreted proteins into small vesicles at the trans-Golgi network by transmembrane cargo receptors…”
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Identification of protamine 1 as a novel cancer‐testis antigen in early chronic lymphocytic leukaemia
Published in British journal of haematology (01-03-2009)“…Summary Early chronic lymphocytic leukaemia (CLL) is an ideal disease for immunotherapy. We previously showed that SEMG 1 is a cancer‐testis (CT) antigen in…”
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TX‐1877, a bifunctional hypoxic cell radiosensitizer, enhances anticancer host response: Immune cell migration and nitric oxide production
Published in International journal of cancer (10-09-2005)“…We investigated in the current study the effect of TX‐1877, a bifunctional hypoxic cell radiosensitizer, in augmenting anticancer host response. In the…”
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Tracking the expression of therapeutic protein targets in rare cells via antibody-mediated nanoparticle labelling and sorting
Published in Nature biomedical engineering (27-07-2020)“…Molecular-level features of tumours can be tracked via single-cell analyses of circulating tumour cells (CTCs). Yet single-cell measurements of protein…”
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Generation of Subcutaneous and Intrahepatic Human Hepatocellular Carcinoma Xenografts in Immunodeficient Mice
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Cloning and subcellular location of an Arabidopsis receptor-like protein that shares common features with protein-sorting receptors of eukaryotic cells
Published in Plant physiology (Bethesda) (01-05-1997)“…Many receptors involved in clathrin-mediated protein transport through the endocytic and secretory pathways of yeast and animal cells share common features…”
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