Search Results - "Ahmed, Mohammad Z."
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Molecular docking analysis of rutin reveals possible inhibition of SARS-CoV-2 vital proteins
Published in Journal of Traditional and Complementary Medicine (01-03-2021)“…Background and aim: COVID-19 emerged by the end of 2019 in Wuhan, China. It spreaded and became a public health emergency all over the world by mid of April…”
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2
Phytochemical characterization, antioxidant and antibacterial activities of crude extracts of Anisomeles malabarica and Coldenia procumbens
Published in Journal of Toxicology and Environmental Health, Part A (02-09-2023)“…The aim of this study was to determine the phytochemical profile, antibacterial and antioxidant activities of crude aqueous leaf extracts of Anisomeles…”
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3
Anti-viral drug discovery against monkeypox and smallpox infection by natural curcumin derivatives: A Computational drug design approach
Published in Frontiers in cellular and infection microbiology (22-03-2023)“…In the last couple of years, viral infections have been leading the globe, considered one of the most widespread and extremely damaging health problems and one…”
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Assessment of the Anticancer Effect of Chlorojanerin Isolated from Centaurothamnus maximus on A549 Lung Cancer Cells
Published in Molecules (Basel, Switzerland) (29-03-2023)“…The goal of this study was to assess the anticancer efficacy of chlorojanerin against various cancer cells. The effects of chlorojanerin on cell cytotoxicity,…”
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Cytotoxicity of Newly Synthesized Quinazoline-Sulfonamide Derivatives in Human Leukemia Cell Lines and Their Effect on Hematopoiesis in Zebrafish Embryos
Published in International journal of molecular sciences (25-04-2022)“…Many quinazoline derivatives with pharmacological properties, such as anticancer activity, have been synthesized. Fourteen quinazoline derivatives bearing a…”
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6
Janerin Induces Cell Cycle Arrest at the G2/M Phase and Promotes Apoptosis Involving the MAPK Pathway in THP-1, Leukemic Cell Line
Published in Molecules (Basel, Switzerland) (13-12-2021)“…Janerin is a cytotoxic sesquiterpene lactone that has been isolated and characterized from different species of the genus. In this study, janerin was isolated…”
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The Antiproliferative and Apoptotic Effects of a Novel Quinazoline Carrying Substituted-Sulfonamides: In Vitro and Molecular Docking Study
Published in Molecules (Basel, Switzerland) (01-02-2022)“…In order to investigate for a new effective and safe anticancer drug, we synthesized a novel series of quinazoline containing biologically active…”
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Novel sulphonamide-bearing methoxyquinazolinone derivatives as anticancer and apoptosis inducers: synthesis, biological evaluation and in silico studies
Published in Journal of enzyme inhibition and medicinal chemistry (01-12-2022)“…We synthesised a new series of sulphonamide-bearing quinazolinone derivatives 5-18 and evaluated their in vitro cytotoxicity in various cancer cell lines…”
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Therapeutic Potential of Withaferin-A and Propolis Combinational Drug Therapy for Breast Cancer: An In Vivo Interpretation for Validating the Antiproliferative Efficacy and Ameliorative Potential in Benzo[a]pyrene-Induced Breast Metastasis
Published in Journal of chemistry (14-05-2024)“…Cancer is a serious health problem, with a rising trend in its occurrence documented globally. Female breast cancer is the most common type of cancer worldwide…”
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10
Sesamol Induces Apoptosis-Like Cell Death in Leishmania donovani
Published in Frontiers in cellular and infection microbiology (28-10-2021)“…Background Visceral leishmaniasis (VL), caused by the protozoan parasite Leishmania donovani ( L. donovani ), is the most severe form of leishmaniasis. It is…”
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Aminoglycosides as potential inhibitors of SARS-CoV-2 main protease: an in silico drug repurposing study on FDA-approved antiviral and anti-infection agents
Published in Journal of infection and public health (01-05-2021)“…The emergence and spread of SARS-CoV-2 throughout the world has created an enormous socioeconomic impact. Although there are several promising drug candidates…”
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12
Spectroscopic and cloud point studies of the interaction and thermodynamics of ciprofloxacin hydrochloride+surfactants mixture in different solvents: Effect of temperature and composition
Published in The Korean journal of chemical engineering (01-07-2021)“…Surfactant is one of the most important chemical entities in drug formulation which can bind with drug molecules. Herein, the binding interaction of…”
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Corrigendum: Anti-viral drug discovery against monkeypox and smallpox infection by natural curcumin derivatives: a computational drug design approach
Published in Frontiers in cellular and infection microbiology (09-06-2023)“…[This corrects the article DOI: 10.3389/fcimb.2023.1157627.]…”
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Effect of Date Palm (Phoenix dactylifera) Phytochemicals on Aβ1−40 Amyloid Formation: An in-silico Analysis
Published in Frontiers in neuroscience (25-07-2022)“…Alzheimer's disease (AD) is a neurodegenerative disease and the most prevalent form of dementia. The generation of oxygen free radicals and oxidative damage is…”
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Chemical profile, antiproliferative and pro-apoptotic activities of essential oils of Pulicaria arabica against A549 lung cancer cell line
Published in Saudi pharmaceutical journal (01-12-2023)“…Pulicaria arabica has been traditionally utilized in folk medicine for various purposes such as ulcer treatments as well as antidiarrheal agent. Herein, the…”
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Deregulation of apoptotic proteins by induction of Dendropthae falcata (L.f.) Ettingsh plant extract in breast cancer cells: A proteome-wide analysis
Published in Iranian journal of basic medical sciences (2023)“…Objective(s): The present study evaluated the protein-based analysis to unravel the role and mechanism behind the Dendropthae falcata plant extract treatment…”
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Revisiting the Flora of Saudi Arabia: Phytochemical and Biological Investigation of the Endangered Plant Species Euphorbia saudiarabica
Published in Metabolites (13-04-2023)“…plants have a significant place in traditional medicine due to their numerous therapeutic properties, including their anti-tumor effects, which have been…”
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Enhanced Apoptosis by Functionalized Highly Reduced Graphene Oxide and Gold Nanocomposites in MCF‑7 Breast Cancer Cells
Published in ACS omega (15-06-2021)“…Graphene nanocomposites have gained significant interest in a variety of biological applications due to their unique properties. Herein, we have studied the…”
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Unprecedented Insights on Chemical and Biological Significance of Euphorbia cactus Growing in Saudi Arabia
Published in Plants (Basel) (02-03-2022)“…Ehrenb ex Boiss. is a plant species reported from central Africa and the southern Arabian Peninsula, belonging to the family of Euphorbiaceae. The plant has…”
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Cell surface expression of Ribophorin I, an endoplasmic reticulum protein, over different cell types
Published in International journal of biological macromolecules (01-04-2024)“…Ribophorin-1 serves as one of the subunits of the oligosaccharyltransferase (OST) complex located in the endoplasmic reticulum (ER). Until now, RPN-1 was…”
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