Search Results - "Ahmed, Atif A."
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Polypyrimidine Tract Binding Protein: A Universal Player in Cancer Development
Published in Current molecular medicine (01-01-2024)“…Polypyrimidine tract binding protein is a 57-Kda protein located in the perinucleolar compartment where it binds RNA and regulates several biological functions…”
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Genomic insights into pediatric intestinal inflammatory and eosinophilic disorders using single-cell RNA-sequencing
Published in Frontiers in immunology (13-08-2024)“…Chronic inflammation of the gastrointestinal tissues underlies gastrointestinal inflammatory disorders, leading to tissue damage and a constellation of painful…”
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Characterization of the Mucosally-Adherent Duodenal Microbiome in Children with and without Crohn's Disease
Published in Pharmaceuticals (Basel, Switzerland) (11-07-2022)“…Manipulation of the microbiome is a rational treatment strategy for inflammatory bowel disease (IBD). Compared to the colon and terminal ileum (TI),…”
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YAP and the Hippo pathway in pediatric cancer
Published in Molecular & cellular oncology (04-05-2017)“…The Hippo pathway is an important signaling pathway that controls cell proliferation and apoptosis. It is evolutionarily conserved in mammals and is stimulated…”
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Tisagenlecleucel infusion in patients with relapsed/refractory ALL and concurrent serious infection
Published in Journal for immunotherapy of cancer (01-01-2021)“…BackgroundTisagenlecleucel, an anti-CD19 chimeric antigen receptor T (CAR-T) cell therapy, has demonstrated durable efficacy and a manageable safety profile in…”
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Expression of therapeutic targets in Ewing sarcoma family tumors
Published in Human pathology (01-07-2012)“…Summary Ewing sarcoma family tumor is an aggressive malignant tumor of bone and soft tissue in children and adolescents. Despite advances in modern therapy,…”
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Use of the Anatomage Virtual Table in Medical Education and as a Diagnostic Tool: An Integrative Review
Published in Curēus (Palo Alto, CA) (10-03-2023)“…Studies on human anatomy mainly depend on cadaver dissection. New technology devices have progressed to improve anatomy teaching, such as the 3D Anatomage…”
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9-Year-old With Altered Mental Status
Published in The Pediatric infectious disease journal (01-11-2023)Get full text
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Neuroblastoma in children: Update on clinicopathologic and genetic prognostic factors
Published in Pediatric hematology and oncology (03-04-2017)“…Neuroblastoma is the most common extracranial solid tumor in childhood accounting for 8-10% of all childhood malignancies. The tumor is characterized by a…”
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Cancer diagnostics: The journey from histomorphology to molecular profiling
Published in Oncotarget (06-09-2016)“…Although histomorphology has made significant advances into the understanding of cancer etiology, classification and pathogenesis, it is sometimes complicated…”
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An Infant Presenting with Seizures and Renal Failure
Published in Clinical chemistry (Baltimore, Md.) (01-02-2021)Get full text
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Claudins in human cancer: a review
Published in Histology and histopathology (01-01-2010)“…Claudins are tight junction proteins that are critical for the sealing of cellular sheets and controlling paracellular ion flux. The claudin family of proteins…”
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Histoplasma osteomyelitis in a 15‐year‐old kidney transplant patient
Published in Transplant infectious disease (01-12-2022)Get full text
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Phase III Trial Adding Vincristine-Topotecan-Cyclophosphamide to the Initial Treatment of Patients With Nonmetastatic Ewing Sarcoma: A Children's Oncology Group Report
Published in Journal of clinical oncology (20-12-2021)“…The primary aim of this phase III randomized trial was to test whether the addition of vincristine, topotecan, and cyclophosphamide (VTC) to interval…”
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Therapy resistance mechanisms in Ewing’s sarcoma family tumors
Published in Cancer chemotherapy and pharmacology (01-04-2014)“…Ewing’s sarcoma family tumors are aggressive small round cell malignancies that arise in bone or soft tissues in adolescents and young adults. The addition of…”
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Grb2-associated binding protein-1 as a biomarker in bone and soft tissue sarcomas
Published in Pathology (01-10-2019)“…The Grb2-associated binding proteins are a family of platform proteins involved in signalling transduction pathways. A major family member, Gab1, modulates the…”
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Normal or reactive minor cell populations in bone marrow and peripheral blood mimic minimal residual leukemia by flow cytometry
Published in Cytometry. Part B, Clinical cytometry (01-09-2021)“…Background Measurable residual disease (MRD) is a strong independent poor prognostic factor for acute leukemia. Multiparameter flow cytometry (FCM) is a…”
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IGF1R immunohistochemistry in Ewing's sarcoma as predictor of response to targeted therapy
Published in International journal of health sciences (01-07-2020)“…Ewing's sarcoma is an aggressive malignancy of bone and soft tissue in children and young adults. Despite advances in modern therapy, metastasis can occur and…”
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Evaluation of Genotypic Antiviral Resistance Testing as an Alternative to Phenotypic Testing in a Patient with DOCK8 Deficiency and Severe HSV-1 Disease
Published in The Journal of infectious diseases (11-06-2020)“…Abstract Antiviral resistance frequently complicates the treatment of herpes simplex virus (HSV) infections in immunocompromised patients. Here we present the…”
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Cuplike nuclear morphology is highly associated with IKZF1 deletion in pediatric precursor B-cell ALL
Published in Blood (18-07-2019)Get full text
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