Search Results - "Ahmed, Amira F."
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Diacerein protects rats with liver ischemia/reperfusion damage: Down-regulation of TLR4/ NFκ-B signaling pathway
Published in Biomedicine & pharmacotherapy (01-02-2021)“…[Display omitted] •Liver ischemia reperfusion injury is an unavoidable problem, still a challenge.•Diacerein exhibits anti-inflammatory, anti-apoptotic and…”
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Low-dose lixisenatide protects against early-onset nephropathy induced in diabetic rats
Published in Life sciences (1973) (15-12-2020)“…Diabetic nephropathy (DN) is the most frequent cause of end-stage renal disease. This study was performed to investigate the possible protective effect of…”
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Role of JNK, ERK, and p38 MAPK signaling pathway in protective effect of sildenafil in cyclophosphamide-induced placental injury in rats
Published in Life sciences (1973) (15-03-2022)“…Chemotherapeutic agents; cyclophosphamide (CYC) is used for treatment of cancer and autoimmune diseases. Grievously, CYC is non-selective as it affects both…”
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BMI relationship to the onset of puberty: assessment of growth parameters and sexual maturity changes in Egyptian children and adolescents of both sexes
Published in Journal of pediatric endocrinology & metabolism : JPEM (28-01-2020)“…Background Puberty is the period of human growth and development. To determine the onset of puberty with regards to the effect of higher adiposity, together…”
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Underlying mechanisms behind the protective effect of angiotensin (1–7) in experimental rat model of ovarian ischemia reperfusion injury
Published in Life sciences (1973) (15-10-2019)“…Ovarian ischemia as a consequence of torsion constitutes a gynecologic emergency affecting females during reproductive age. Its management by detorsion results…”
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TLR4/ MyD88/NF-κB signaling pathway involved in the protective effect of diacerein against lung fibrosis in rats
Published in Human & experimental toxicology (01-08-2023)“…Purpose Pulmonary fibrosis (PF) is an inescapable problem. Diacerein, a chondro-protective drug, has antioxidant and anti-inflammatory effects. Its effect on…”
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Role of nitric oxide in mediating the cardioprotective effect of agomelatine against isoproterenol-induced myocardial injury in rats
Published in Naunyn-Schmiedeberg's archives of pharmacology (01-10-2020)“…Myocardial infarction (M/I) is a common cause of mortality worldwide. Agomelatine (AGO), a potent melatonin receptor agonist, proved to have…”
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Preparation and Evaluation of Atorvastatin-Loaded Nanoemulgel on Wound-Healing Efficacy
Published in Pharmaceutics (13-11-2019)“…Tissue repair and wound healing are complex processes that involve inflammation, granulation, and remodeling of the tissue. The potential of various statins…”
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The IL-6/HO-1/STAT3 signaling pathway is implicated in the amelioration of acetaminophen-induced hepatic toxicity: A neonatal rat model
Published in Human & experimental toxicology (01-01-2023)“…The widespread use of acetaminophen (APAP) in children as an over-the-counter treatment can cause acute liver failure through accidental overdose or ingestion…”
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Idebenone regulates sirt1/Nrf2/TNF-α pathway with inhibition of oxidative stress, inflammation, and apoptosis in testicular torsion/detorsion in juvenile rats
Published in Human & experimental toxicology (01-05-2022)“…Testicular torsion is an emergency, mainly in newborn and adolescent males, resulting in testicular ischemia. The current study aimed to evaluate the effect of…”
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