Search Results - "Ahmed, Amany"
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Mechanistic insights into the protective effects of chlorogenic acid against indomethacin-induced gastric ulcer in rats: Modulation of the cross talk between autophagy and apoptosis signaling
Published in Life sciences (1973) (15-06-2021)“…This study aimed to investigate the gastroprotective effect of chlorogenic acid (CGA) against Indomethacin (IND)-induced gastric ulcer (GU) in rats and its…”
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2
Acetyl-11-keto-β-boswellic acid prevents testicular torsion/detorsion injury in rats by modulating 5-LOX/LTB4 and p38-MAPK/JNK/Bax/Caspase-3 pathways
Published in Life sciences (1973) (01-11-2020)“…Testicular torsion/detorsion (T/D) is a critical medical condition that necessitates prompt surgical intervention to avoid testicular atrophy and infertility…”
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3
Enhanced upregulation of SIRT1 via pioglitazone and ligustrazine confers protection against ethanol-induced gastric ulcer in rats
Published in Naunyn-Schmiedeberg's archives of pharmacology (01-08-2024)“…Gastric ulcer is a disturbing disease that impacts many people worldwide. Pioglitazone (Piog), a thiazolidinedione, and ligustrazine (Ligu), a natural…”
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4
Sertraline Pre-Treatment Attenuates Hemorrhagic Transformation Induced in Rats after Cerebral Ischemia Reperfusion via Down Regulation of Neuronal CD163: Involvement of M1/M2 Polarization Interchange and Inhibiting Autophagy
Published in Journal of neuroimmune pharmacology (01-12-2023)“…Cerebral ischemia reperfusion (I/R) is one of the neurovascular diseases which leads to severe brain deterioration. Haemorrhagic transformation (HT) is the…”
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5
Protective effects of febuxostat against paraquat-induced lung toxicity in rats: Impact on RAGE/PI3K/Akt pathway and downstream inflammatory cascades
Published in Life sciences (1973) (15-03-2019)“…The herbicide paraquat causes fatal lung toxicity by induction of xanthine oxidase, production of free radicals and inflammation. Febuxostat, a xanthine…”
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6
Dapagliflozin, an SGLT2 inhibitor, ameliorates acetic acid-induced colitis in rats by targeting NFκB/AMPK/NLRP3 axis
Published in Inflammopharmacology (01-08-2021)“…The development of effective treatment strategies has been hindered by the complex pathogenesis of ulcerative colitis (UC). UC patients treated with current…”
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7
ERK activation by zeranol has neuroprotective effect in cerebral ischemia reperfusion
Published in Life sciences (1973) (15-06-2019)“…Incidence of stroke increases in postmenopausal women with dangerous consequences. In this study we used zeranol to protect ovariectomized (OVX) rats against…”
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8
Sitagliptin attenuates intestinal ischemia/reperfusion injury via cAMP/PKA, PI3K/Akt pathway in a glucagon-like peptide 1 receptor-dependent manner
Published in Life sciences (1973) (15-10-2018)“…This study investigated the effect of sitagliptin prophylactic treatment on intestinal I/R rat model and explored the possible underlying mechanism. Forty-five…”
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9
Pomegranate extract protects against cerebral ischemia/reperfusion injury and preserves brain DNA integrity in rats
Published in Life sciences (1973) (21-08-2014)“…Interruption to blood flow causes ischemia and infarction of brain tissues with consequent neuronal damage and brain dysfunction. Pomegranate extract is well…”
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10
Effect of hypothyroidism on contractile performance of isolated end-stage failing human myocardium
Published in PloS one (11-04-2022)“…The relationship between hypothyroidism and the occurrence and progression of heart failure (HF) has had increased interest over the past years. The low T3…”
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11
Akt / GSK3β / Nrf2 / HO-1 pathway activation by flurbiprofen protects the hippocampal neurons in a rat model of glutamate excitotoxicity
Published in Neuropharmacology (15-09-2021)“…Nuclear factor erythroid 2-related factor 2 (Nrf2) is a transcription factor that regulates redox homeostasis of the cell through regulation of the antioxidant…”
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12
Effect of bempedoic acid on angiotensin-II induced hypertension and vascular tissue remodelling in renal hypertensive rats through AMPK multiple signalling pathways modulation
Published in Life sciences (1973) (01-05-2023)“…Angiotensin II (Ang II), the effector of the renin-angiotensin system (RAS), is a key player in the pathogenesis of chronic hypertension, accompanied by…”
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13
Targeting the adenosine monophosphate-activated protein kinase signalling pathway by bempedoic acid attenuates Angiotensin II-induced cardiac remodelling in renovascular hypertension in rats
Published in Life sciences (1973) (15-09-2023)“…The crosstalk between the renin-angiotensin system and Adenosine monophosphate-activated protein kinase (AMPK) gained significant interest due to their…”
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14
Lixisenatide Reduced Damage in Hippocampus CA1 Neurons in a Rat Model of Cerebral Ischemia-Reperfusion Possibly Via the ERK/P38 Signaling Pathway
Published in Journal of molecular neuroscience (01-07-2020)“…Glucagon-like peptide-1 (GLP-1) is a gut-derived peptide that has various physiological actions. One of its main actions is the regulation of blood glucose…”
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15
Effect of hexavalent chromium exposure on the liver and kidney tissues related to the expression of CYP450 and GST genes of Oreochromis niloticus fish: Role of curcumin supplemented diet
Published in Ecotoxicology and environmental safety (30-01-2020)“…The present study evaluated the adverse effects of the hexavalent chromium (Cr (VI)) at sub-lethal concentrations and the ameliorative potential of curcumin…”
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Nursing Informatics Competencies Among Nursing Students and Their Relationship to Patient Safety Competencies: Knowledge, Attitude, and Skills
Published in Computers, informatics, nursing (01-11-2015)“…With implementation of information technology in healthcare settings to promote safety and evidence-based nursing care, a growing emphasis on the importance of…”
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Dimethyl fumarate interferes with MyD88‐dependent toll‐like receptor signalling pathway in isoproterenol‐induced cardiac hypertrophy model
Published in Journal of pharmacy and pharmacology (01-11-2018)“…Objectives To investigate the effect of dimethyl fumarate (DMF) on Toll‐like receptor (TLR) signalling pathway in isoproterenol (ISO)‐induced cardiac…”
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Ethyl pyruvate attenuates isoproterenol-induced myocardial infarction in rats: Insight to TNF-α-mediated apoptotic and necroptotic signaling interplay
Published in International immunopharmacology (01-02-2022)“…Effect of ethyl pyruvate on tumor necrosis factor receptor pathway of apoptosis and necroptosis. Complex 1: RIPK1 ubiquitinated and deactivated by cIAPs to…”
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19
The protective effect of zeranol in cerebral ischemia reperfusion via p-CREB overexpression
Published in Life sciences (1973) (15-01-2019)“…Cerebral ischemia reperfusion (I/R) is a neurovascular disease leading to cerebral damage. It was found that postmenopausal women are liable to more dangerous…”
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20
The effects of chitosan-vitamin C nanocomposite supplementation on the growth performance, antioxidant status, immune response, and disease resistance of Nile tilapia (Oreochromis niloticus) fingerlings
Published in Aquaculture (15-03-2021)“…This study was performed to investigate the effect of the dietary supplementation of chitosan-vitamin C nanocomposite (CVCN) at four different concentrations…”
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