Search Results - "Ahmadian, M.R."
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1
662 Mitotic spindle stress elicited by TACC3 depletion as a major trigger of premature senescence
Published in European journal of cancer supplements (2010)Get full text
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Critical off‐target effects of the widely used Rac1 inhibitors NSC23766 and EHT1864 in mouse platelets
Published in Journal of thrombosis and haemostasis (01-05-2015)“…Summary Background Platelet aggregation at sites of vascular injury is essential for normal hemostasis, but may also cause pathologic vessel occlusion. Rho…”
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3
470P Anti-tumor mechanisms of rigosertib in colorectal cancer
Published in Annals of oncology (01-09-2020)Get full text
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4
Allosteric regulation of GRB2 modulates RAS activation
Published in Small GTPases (2022)“…RAS activation is a multiple-step process in which linkage of the extracellular stimuli to the RAS activator SOS1 is the main step in RAS activation. GRB2…”
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Loss-of-function mutations within the IL-2 inducible kinase ITK in patients with EBV-associated lymphoproliferative diseases
Published in Leukemia (01-05-2012)“…The purpose of this study was the appraisal of the clinical and functional consequences of germline mutations within the gene for the IL-2 inducible T-cell…”
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6
Specific mosaic KRAS mutations affecting codon 146 cause oculoectodermal syndrome and encephalocraniocutaneous lipomatosis
Published in Clinical genetics (01-10-2016)“…Oculoectodermal syndrome (OES) and encephalocraniocutaneous lipomatosis (ECCL) are rare disorders that share many common features, such as epibulbar dermoids,…”
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7
The centrosomal protein TACC3 controls paclitaxel sensitivity by modulating a premature senescence program
Published in Oncogene (18-11-2010)“…Microtubule-interfering cancer drugs such as paclitaxel (PTX) often cause chemoresistance and severe side effects, including neurotoxicity. To explore…”
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Dosimetric characteristics of 192Ir sources used in interstitial brachytherapy
Published in Applied radiation and isotopes (01-08-2001)“…Dosimetric quantities of 192Ir seed (5 mm length) and wire (10 mm length) brachytherapy sources have been determined. The quantities were measured based on the…”
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Allosteric regulation of GRB2 modulates RAS activation
Published in Small GTPases (31-12-2022)“…RAS activation is a multiple-step process in which linkage of the extracellular stimuli to the RAS activator SOS1 is the main step in RAS activation. GRB2…”
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Overproduction of the Thermus thermophilus elongation factor Tu in Escherichia coli
Published in Biochimie (01-07-1991)“…The elongation factor Tu (EF-Tu) encoded by the tufl gene of the extreme thermophilic bacterium Thermus thermophilus HB8 was expressed under control of the tac…”
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