Search Results - "Ahmad Khan, Faiyaz"

Fanconi-Bickel Syndrome: A Review of the Mechanisms That Lead to Dysglycaemia by Sharari, Sanaa, Abou-Alloul, Mohamad, Hussain, Khalid, Ahmad Khan, Faiyaz

“…Accumulation of glycogen in the kidney and liver is the main feature of Fanconi-Bickel Syndrome (FBS), a rare disorder of carbohydrate metabolism inherited in…”
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Understanding the Mechanism of Diabetes Mellitus in a LRBA-Deficient Patient by Hawari, Iman, Ericsson, Johan, Kabeer, Basirudeen Syed Ahamed, Chaussabel, Damien, Alsulaiti, Asma, Sharari, Sanaa A, Maccalli, Cristina, Khan, Faiyaz Ahmad, Hussain, Khalid

“…The scope of this study is to show that DM in a LRBA-deficient patient with a stop codon mutation (c.3999 G > A) was not mediated through autoimmunity. We have…”
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Phosphodiesterase 3B (PDE3B) Regulates NLRP3 Inflammasome and Metabolic Cross Talk in Adipose Tissue by Khan, Faiyaz Ahmad, Chung, Youn Wook, Tang, Yan, Hockman, Steven C, Liu, Steve, Khan, Yusuf, Huo, Kevin, Amar, Marcelo J, Remaley, Alan T, Manganiello, Vincent C

“…Abstract only Activation of inflammation in white adipose tissue (WAT) which includes infiltration/expansion of WAT macrophages contributes to pathogenesis of…”
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Effects of SRT1720 (SRT) and Resveratrol (RSV) on AMP‐activated protein kinase (AMPK) and PKA‐signaling in Adipocytes: Roles for Phosphodiesterase (PDE) (3 and 4) by KHAN, FAIYAZ AHMAD, Park, Sung‐Jun, Chung, Jay H, Manganiello, Vincent c

“…Abstract only SIRT1 activators, SRT and RSV mimic effects of caloric restriction (CR) in lower organisms and mice. In 3T3‐L1 adipocytes, SRT and RSV inhibited…”
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PKA‐induced Interaction of Phosphorylated PDE3A (pPDE3A) and BIG1 (Brefeldin A‐inhibited guanine nucleotide exchange protein 1) in Cytosolic Fractions from Human Myocardium may be Important in Regulation of BIG1 Function by Khan, Faiyaz Ahmad, Szabo-Fresnais, Nicolas, Krall, Judy, Moss, Joel, Vaughan, Martha, Movsesian, Matthew, Manganiello, Vincent

“…Abstract only BIG1 and BIG2 proteins, which contain A‐kinase anchoring protein (AKAP) motifs, catalyze activation of class I ARFs (ADP‐ribosylation factors) by…”
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The Roles of Serine/Threonine Protein Phosphatases in Regulation of PDE3B Signaling in 3T3‐L1 Adipocytes by Khan, Faiyaz Ahmad, Zmuda‐Trzebiatowska, Emilia, Degerman, Eva, Manganiello, Vincent

“…Abstract only Using sucrose gradient centrifugation and confocal microscopy, PDE3B was localized in internal membranes and PM in adipocytes. PDE3B is…”
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Subcellular Localization of Human Myocardial PDE3 Isoforms and Components of cAMP Signaling Pathways by Khan, Faiyaz Ahmad, Krall, Judith, Vandeput, Fabrice, Shen, Weixing, Manganiello, Vincent, Movsesian, Matthew

“…Abstract only Caveolae‐enriched plasma membrane (PM) fractions from failing heart myocardium are highly enriched in b2‐ARs, b3‐ARs, Gα (i), adenylyl cyclase…”
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In PDE3B KO mice, White Adipose Tissue (WAT) Exhibits Characteristics of “Good Fat,” i.e., Brown Adipose Tissue (BAT): II. Alterations in Angiogenesis and cAMP‐and AMP Kinase‐signaling by Khan, Faiyaz Ahmad, tang, Yan, Chung, Youn Wook, Zmuda‐Trzebiatowska, Emilia, Hockman, Steve, Gavrilova, Oksana, Berger, Karin, Degerman, Eva, Manganiello, Vincent

“…Abstract only Obesity is a major risk factor for type 2 diabetes and cardiovascular disease. WAT affects body fat and energy utilization via storage and…”
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Differential regulation of adipocyte PDE3B in distinct membrane compartments in response to insulin and CL316243 by Khan, Faiyaz Ahmad, Lindh, Rebecka, Tang, Yan, Ruishalme, Lida, Ost, Anita, Stalfors, Peter, Degerman, Eva, Manganiello, Vincent

“…Abstract only PDE3B is activated by insulin and CL (CL316243, a b3‐receptor agonist) in adipocytes via PKB‐ and PKA‐ signaling, respectively. Activation of…”
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Insulin‐induced formation of macromolecular complexes involved in activation of Phosphodiesterase3B (PDE3B) in 3T3‐L1 adipocytes by Khan, Faiyaz Ahmad, Nilsson, Rebecka, Tang, Yan, Degerman, Eva, Manganiello, Vincent C

“…PDE3B is an important regulator of several insulin‐ and cAMP‐dependent signaling pathways. Fractionation of membranes from adipocytes revealed that PDE3B was…”
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