Search Results - "Ahmad Fuaad, Abdullah"

Peptide conjugation via CuAAC 'click' chemistry by Ahmad Fuaad, Abdullah A H, Azmi, Fazren, Skwarczynski, Mariusz, Toth, Istvan

“…The copper (I)-catalyzed alkyne azide 1,3-dipolar cycloaddition (CuAAC) or 'click' reaction, is a highly versatile reaction that can be performed under a…”
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The Use of Microwave-Assisted Solid-Phase Peptide Synthesis and Click Chemistry for the Synthesis of Vaccine Candidates Against Hookworm Infection by Fuaad, Abdullah A H Ahmad, Skwarczynski, Mariusz, Toth, Istvan

“…A protein-based vaccine approach against hookworm infection has failed to deliver the expected outcome, due to a problem with an allergic response in the…”
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Nanoparticle tools to improve and advance precision practices in the Agrifoods Sector towards sustainability - A review by Lang, Claudia, Mission, Elaine Gabutin, Ahmad Fuaad, Abdullah Al-Hadi, Shaalan, Mohamed

“…Common agricultural pest and pathogen management practices are reliant on agrochemicals (pesticides, herbicides, and fertilizers), drugs and synthetic…”
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Polymer-peptide hybrids as a highly immunogenic single-dose nanovaccine by Ahmad Fuaad, Abdullah A H, Jia, Zhongfan, Zaman, Mehfuz, Hartas, Jon, Ziora, Zyta M, Lin, I-Chun, Moyle, Peter M, Batzloff, Michael R, Good, Michael F, Monteiro, Michael J, Skwarczynski, Mariusz, Toth, Istvan

“…To explore four-arm star poly(t-butyl)acrylate (P(t)BA)-peptide and linear P(t)BA-peptide conjugates as a vaccine-delivery system against Group A…”
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The use of a conformational cathepsin D-derived epitope for vaccine development against Schistosoma mansoni by Ahmad Fuaad, Abdullah A.H., Roubille, Romain, Pearson, Mark S., Pickering, Darren A., Loukas, Alex C., Skwarczynski, Mariusz, Toth, Istvan

“…[Display omitted] Schistosomiasis is caused by the infection from Schistosoma species. Among these, Schistosoma mansoni is one of the major species that…”
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Recent Progress on Nanocarriers for Topical-Mediated RNAi Strategies for Crop Protection-A Review by Mat Jalaluddin, Nurzatil Sharleeza, Asem, Maimunah, Harikrishna, Jennifer Ann, Ahmad Fuaad, Abdullah Al Hadi

“…To fulfil the growing needs of the global population, sustainability in food production must be ensured. Insect pests and pathogens are primarily responsible…”
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DENV-Mimetic Polymersome Nanoparticles Bearing Multi-Epitope Lipopeptides Antigen as the Next-Generation Dengue Vaccine by Abdul Rahman, Nur Adilah, Mohamad Norpi, Abdin Shakirin, Nordin, Muhammad Luqman, Mohd Amin, Mohd Cairul Iqbal, Ahmad Fuaad, Abdullah Al-Hadi, Muhammad Azami, Nor Azila, Marasini, Nirmal, Azmi, Fazren

“…Dengue remains a severe threat to public health. The safety and efficacy of the licensed dengue vaccine is not clinically satisfactory, which necessitate the…”
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Inhibition of SARS-CoV-2 3CL protease by the anti-viral chimeric protein RetroMAD1 by Chan, Lee-Chin, Mat Yassim, Aini Syahida, Ahmad Fuaad, Abdullah Al Hadi, Leow, Thean Chor, Sabri, Suriana, Radin Yahaya, Radin Shafierul, Abu Bakar, Awang Muhammad Sagaf

“…COVID-19 results from SARS-CoV-2, which mutates frequently, challenging current treatments. Therefore, it is critical to develop new therapeutic drugs against…”
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Hit-to-Lead Short Peptides against Dengue Type 2 Envelope Protein: Computational and Experimental Investigations by Zaidi, Norburhanuddin Johari, Abdullah, Adib Afandi, Heh, Choon Han, Lin, Chun-Hung, Othman, Rozana, Ahmad Fuaad, Abdullah Al Hadi

“…Data from the World Health Organisation show that the global incidence of dengue infection has risen drastically, with an estimated 400 million cases of dengue…”
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Development of Novel Melanocortin Receptor Agonists Based on the Cyclic Peptide Framework of Sunflower Trypsin Inhibitor‑1 by Durek, Thomas, Cromm, Philipp M, White, Andrew M, Schroeder, Christina I, Kaas, Quentin, Weidmann, Joachim, Ahmad Fuaad, Abdullah, Cheneval, Olivier, Harvey, Peta J, Daly, Norelle L, Zhou, Yang, Dellsén, Anita, Österlund, Torben, Larsson, Niklas, Knerr, Laurent, Bauer, Udo, Kessler, Horst, Cai, Minying, Hruby, Victor J, Plowright, Alleyn T, Craik, David J

“…Ultrastable cyclic peptide frameworks offer great potential for drug design due to their improved bioavailability compared to their linear analogues. Using the…”
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Recent progress in adjuvant discovery for peptide-based subunit vaccines by Azmi, Fazren, Ahmad Fuaad, Abdullah Al Hadi, Skwarczynski, Mariusz, Toth, Istvan

“…Peptide-based subunit vaccines are of great interest in modern immunotherapy as they are safe, easy to produce and well defined. However, peptide antigens…”
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Self-adjuvanting vaccine against group A streptococcus: Application of fibrillized peptide and immunostimulatory lipid as adjuvant by Azmi, Fazren, Ahmad Fuaad, Abdullah Al Hadi, Giddam, Ashwini Kumar, Batzloff, Michael R., Good, Michael F., Skwarczynski, Mariusz, Toth, Istvan

“…A B-cell epitope was incorporated into three potentially self-adjuvanting vaccine delivery systems and self-assembled into nanoparticles. The presence of two…”
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New modular platform based on multi-adjuvanted amphiphilic chitosan nanoparticles for efficient lipopeptide vaccine delivery against group A streptococcus by Norpi, Abdin Shakirin Mohamad, Nordin, Muhammad Luqman, Ahmad, Nuraziemah, Katas, Haliza, Fuaad, Abdullah Al-Hadi Ahmad, Sukri, Asif, Marasini, Nirmal, Azmi, Fazren

“…An effective vaccine against group A streptococcus (GAS) is highly desirable for definitive control of GAS infections. In the present study, two variants of…”
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Lipopeptide Nanoparticles: Development of Vaccines against Hookworm Parasite by Fuaad, Abdullah A. H. Ahmad, Pearson, Mark S., Pickering, Darren A., Becker, Luke, Zhao, Guangzu, Loukas, Alex C., Skwarczynski, Mariusz, Toth, Istvan

“…Necator americanus (hookworm) infects over half a billion people worldwide. Anthelminthic drugs are commonly used to treat the infection; however, vaccination…”
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Computational-aided design: minimal peptide sequence to block dengue virus transmission into cells by Arumugam, Aathe Cangaree, Agharbaoui, Fatima Ezzahra, Khazali, Ahmad Suhail, Yusof, Rohana, Abd Rahman, Noorsaadah, Ahmad Fuaad, Abdullah Al Hadi

“…Dengue virus (DV) infection is one of the main public health concerns, affecting approximately 390 million people worldwide, as reported by the World Health…”
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Melanocortin 1 Receptor Agonists Based on a Bivalent, Bicyclic Peptide Framework by Durek, Thomas, Kaas, Quentin, White, Andrew M, Weidmann, Joachim, Fuaad, Abdullah Ahmad, Cheneval, Olivier, Schroeder, Christina I, de Veer, Simon J, Dellsén, Anita, Österlund, Torben, Larsson, Niklas, Knerr, Laurent, Bauer, Udo, Plowright, Alleyn T, Craik, David J

“…We have designed a new class of highly potent bivalent melanocortin receptor ligands based on the nature-derived bicyclic peptide sunflower trypsin inhibitor 1…”
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Back Cover: Lipopeptide Nanoparticles: Development of Vaccines against Hookworm Parasite (ChemMedChem 10/2015) by Fuaad, Abdullah A. H. Ahmad, Pearson, Mark S., Pickering, Darren A., Becker, Luke, Zhao, Guangzu, Loukas, Alex C., Skwarczynski, Mariusz, Toth, Istvan

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Synthesis and Characterisation of Self-Assembled and Self-Adjuvanting Asymmetric Multi-Epitope Lipopeptides of Ovalbumin by Eskandari, Sharareh, Stephenson, Rachel J., Fuaad, Abdullah Ahmad, Apte, Simon H., Doolan, Denise L., Toth, Istvan

“…Designing a lipopeptide (LP) vaccine with a specific asymmetric arrangement of epitopes may result in an improved display of antigens, increasing host‐cell…”
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Next-generation Dengue Vaccines: Leveraging Peptide-Based Immunogens and Advanced Nanoparticles as Delivery Platforms by Rahman, Nur Adilah Abdul, Fuaad, Abdullah Al-Hadi Ahmad, Azami, Nor Azila Muhammad, Amin, Mohd Cairul Iqbal Mohd, Azmi, Fazren

“…Dengue, caused by the dengue virus (DENV), is a prevalent arthropod-borne disease in humans and poses a significant burden on public health. Severe cases of…”
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