Search Results - "Ahmad, Rasheed"
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Obesity Is a Positive Modulator of IL-6R and IL-6 Expression in the Subcutaneous Adipose Tissue: Significance for Metabolic Inflammation
Published in PloS one (22-07-2015)“…The role of IL-6R/IL-6 axis in metabolic inflammation remains controversial. We determined the changes in adipose tissue expression of IL-6R and IL-6 in obese,…”
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Advanced Gold Nanomaterials for Photothermal Therapy of Cancer
Published in Journal of nanoscience and nanotechnology (01-01-2016)“…Photothermal therapy represents a non-invasive therapeutic tool to eradicate cancer tumor with minimum toxic effects. In this ablative therapy, accurate…”
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The Cooperative Induction of CCL4 in Human Monocytic Cells by TNF-α and Palmitate Requires MyD88 and Involves MAPK/NF-κB Signaling Pathways
Published in International journal of molecular sciences (19-09-2019)“…Chronic low-grade inflammation, also known as metabolic inflammation, is a hallmark of obesity and parallels with the presence of elevated circulatory levels…”
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ROS/TNF-α Crosstalk Triggers the Expression of IL-8 and MCP-1 in Human Monocytic THP-1 Cells via the NF-κB and ERK1/2 Mediated Signaling
Published in International journal of molecular sciences (01-10-2021)“…IL-8/MCP-1 act as neutrophil/monocyte chemoattractants, respectively. Oxidative stress emerges as a key player in the pathophysiology of obesity. However, it…”
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Metabolic Inflammation and Cellular Immunity
Published in Cells (Basel, Switzerland) (01-06-2023)“…Metabolic and immune cell responses are intimately linked and cross-regulated [...]…”
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Biological transformations of steroidal compounds: A review
Published in Steroids (01-10-2012)“…► Microbial transformation is an important tool for structural modification of compounds. ► Steroidal compounds are responsible for important biological…”
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DFT study of superhalogen and superalkali doped graphitic carbon nitride and its non-linear optical properties
Published in RSC advances (17-02-2021)“…DFT calculations are carried out to investigate nonlinear optical (NLO) properties of superhalogen (BCl 4 ) and superalkali (NLi 4 ) doped graphitic carbon…”
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Palmitate Activates CCL4 Expression in Human Monocytic Cells via TLR4/MyD88 Dependent Activation of NF-κB/MAPK/ PI3K Signaling Systems
Published in Cellular physiology and biochemistry (01-01-2018)“…Background/Aims: Obesity is associated with adipose tissue inflammation which plays a key role in the development of insulin resistance and type 2 diabetes…”
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Increased Expression of the Innate Immune Receptor TLR10 in Obesity and Type-2 Diabetes: Association with ROS-Mediated Oxidative Stress
Published in Cellular physiology and biochemistry (01-01-2018)“…Background/Aims: Metabolic diseases such as obesity and type-2 diabetes (T2D) are known to be associated with chronic low-grade inflammation called metabolic…”
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LPS Induces GM-CSF Production by Breast Cancer MDA-MB-231 Cells via Long-Chain Acyl-CoA Synthetase 1
Published in Molecules (Basel, Switzerland) (14-10-2020)“…Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a monomeric glycoprotein that has been implicated in the tumor growth and progression of different…”
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Endoplasmic Reticulum Stress Promotes the Expression of TNF-α in THP-1 Cells by Mechanisms Involving ROS/CHOP/HIF-1α and MAPK/NF-κB Pathways
Published in International journal of molecular sciences (01-10-2023)“…Obesity and metabolic syndrome involve chronic low-grade inflammation called metabolic inflammation as well as metabolic derangements from increased endotoxin…”
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IRF3 promotes adipose inflammation and insulin resistance and represses browning
Published in The Journal of clinical investigation (01-08-2016)“…The chronic inflammatory state that accompanies obesity is a major contributor to insulin resistance and other dysfunctional adaptations in adipose tissue…”
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Anthracene and Pyrene Biodegradation Performance of Marine Sponge Symbiont Bacteria Consortium
Published in Molecules (Basel, Switzerland) (13-11-2021)“…Every petroleum-processing plant produces sewage sludge containing several types of polycyclic aromatic hydrocarbons (PAHs). The degradation of PAHs via…”
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Synergistic end-capped engineering on non-fused thiophene ring-based acceptors to enhance the photovoltaic properties of organic solar cells
Published in RSC advances (25-04-2022)“…In this study, a series of non-fused thiophene ring-based small molecular acceptors ( 4T1-4T7 ) of A-D-A type are developed by the replacement of the…”
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Ceramide kinase regulates TNF-α-induced immune responses in human monocytic cells
Published in Scientific reports (15-04-2021)“…Ceramide kinase (CERK) phosphorylates ceramide to produce ceramide-1-phosphate (C1P), which is involved in the development of metabolic inflammation. TNF-α…”
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Editorial: Cardiometabolic diseases in postmenopausal women
Published in Frontiers in endocrinology (Lausanne) (07-11-2024)Get full text
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Elevated adipose tissue associated IL-2 expression in obesity correlates with metabolic inflammation and insulin resistance
Published in Scientific reports (01-10-2020)“…Adipose tissue (AT) associated cytokines are involved in the development of chronic low-grade inflammation in obese individuals. IL-2, a pleiotropic cytokine,…”
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A Cross-Sectional Study to Examine the Psychological Impact of the COVID-19 Pandemic on Healthcare Workers in Kuwait
Published in International journal of environmental research and public health (23-08-2022)“…In this study, we aimed to evaluate the psychological impact of the COVID-19 pandemic on healthcare workers to determine the prevalence of symptoms of…”
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TNF-α/Stearate Induced H3K9/18 Histone Acetylation Amplifies IL-6 Expression in 3T3-L1 Mouse Adipocytes
Published in International journal of molecular sciences (20-06-2024)“…Extensive evidence supports the connection between obesity-induced inflammation and the heightened expression of IL-6 adipose tissues. However, the mechanism…”
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TNFα induces matrix metalloproteinase-9 expression in monocytic cells through ACSL1/JNK/ERK/NF-kB signaling pathways
Published in Scientific reports (01-09-2023)“…Studies have established the association between increased plasma levels of matrix metalloproteinase (MMP)-9 and adipose tissue inflammation. Tumor necrosis…”
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