Search Results - "Ahmad, Raise"
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G Protein-Coupled Receptors in Taste Physiology and Pharmacology
Published in Frontiers in pharmacology (30-11-2020)“…Heterotrimeric G protein-coupled receptors (GPCRs) comprise the largest receptor family in mammals and are responsible for the regulation of most physiological…”
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Hunting for the function of orphan GPCRs – beyond the search for the endogenous ligand
Published in British journal of pharmacology (01-07-2015)“…Seven transmembrane‐spanning proteins (7TM), also called GPCRs, are among the most versatile and evolutionary successful protein families. Out of the 400…”
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GPR50-Ctail cleavage and nuclear translocation: a new signal transduction mode for G protein-coupled receptors
Published in Cellular and molecular life sciences : CMLS (01-12-2020)“…Transmission of extracellular signals by G protein-coupled receptors typically relies on a cascade of intracellular events initiated by the activation of…”
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Orphan GPR61, GPR62 and GPR135 receptors and the melatonin MT2 receptor reciprocally modulate their signaling functions
Published in Scientific reports (21-08-2017)“…Understanding the function of orphan G protein-coupled receptors (GPCRs), whose cognate ligand is unknown, is of major importance as GPCRs are privileged drug…”
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Objective Measurements Associated with the Preferred Eating Qualities of Fermented Salamis
Published in Foods (26-08-2021)“…The development of new food products can be expedited by understanding the physicochemical attributes that are most relevant to consumers. Although many…”
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The orphan GPR50 receptor promotes constitutive TGFβ receptor signaling and protects against cancer development
Published in Nature communications (23-03-2018)“…Transforming growth factor-β (TGFβ) signaling is initiated by the type I, II TGFβ receptor (TβRI/TβRII) complex. Here we report the formation of an alternative…”
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Generation and identification of kokumi compounds and their validation by taste-receptor assay: An example with dry-cured lamb meat
Published in Food Chemistry: X (30-03-2022)“…•Fifteen ɤ-glutamyl dipeptides (GGP) were identified in meat crust hydrolysate.•In vitro cell based CaSR assay was applied to measure kokumi tastants…”
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Melatonin MT1 and MT2 receptor ERK signaling is differentially dependent on Gi/o and Gq/11 proteins
Published in Journal of pineal research (01-05-2020)“…G protein‐coupled receptors (GPCRs) transmit extracellular signals into cells by activating G protein‐ and β‐arrestin‐dependent pathways. Extracellular…”
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Investigation of free amino acids in lactic acid bacteria fermented milk and their ability to activate the calcium sensing receptor
Published in International dairy journal (01-06-2023)“…A fullness in sensorial response is sought in low fat dairy foods to improve palatability, which may be achieved through activation of the calcium sensing…”
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Photoperiodic regulation of MT1 and MT2 melatonin receptor expression in spleen and thymus of a tropical rodent Funambulus pennanti during reproductively active and inactive phases
Published in Chronobiology international (01-04-2010)“…Photoperiodic regulation of melatonin receptor types on target tissues, such as lymphatic organs, has never been explored for any seasonal breeder. In the…”
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Immune responses to lipopolysaccharide challenge in a tropical rodent (Funambulus pennanti): photoperiod entrainment and sex differences
Published in Stress (Amsterdam, Netherlands) (01-03-2012)“…Annual variation in day length (photoperiod) triggers changes in the immune system of seasonal breeders. The rationale behind this study was to delineate any…”
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Comparative analysis of kokumi tastant intensity from mechanically deboned meat across three species through in vitro calcium‐sensing receptor activity
Published in International journal of food science & technology (01-11-2024)“…Summary The emergence of kokumi sensation as a flavour enhancer prompted the search for cost effective and the sustainable production of kokumi flavour…”
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Photoperiodic regulation of nuclear melatonin receptor RORα in lymphoid organs of a tropical rodent Funambulus pennanti: Role in seasonal oxidative stress
Published in Journal of photochemistry and photobiology. B, Biology (01-01-2015)“…•Short days enhanced the total antioxidant status of blood and lymphoid tissues.•High plasma melatonin induced AA-NAT activity in the lymphoid tissues.•RORα…”
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Effect of intra-testicular melatonin injection on testicular functions, local and general immunity of a tropical rodent Funambulus pennanti
Published in Endocrine (01-06-2010)“…Local antigonadotrophic action of melatonin in testes has never been correlated with local and general immune status of any rodent. Intra-testicular injection…”
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Melatonin MT 1 and MT 2 receptor ERK signaling is differentially dependent on G i/o and G q/11 proteins
Published in Journal of pineal research (01-05-2020)“…G protein-coupled receptors (GPCRs) transmit extracellular signals into cells by activating G protein- and β-arrestin-dependent pathways. Extracellular…”
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Melatonin receptors limit dopamine reuptake by regulating dopamine transporter cell-surface exposure
Published in Cellular and molecular life sciences : CMLS (01-12-2018)“…Melatonin, a neuro-hormone released by the pineal gland, has multiple effects in the central nervous system including the regulation of dopamine (DA) levels,…”
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Age dependent expression of melatonin membrane receptor (MT1, MT2) and its role in regulation of nitrosative stress in tropical rodent Funambulus pennanti
Published in Free radical research (01-02-2012)“…Age-dependent declining level of melatonin induces free radical load and thereby deteriorates immune function. However, reports are lacking about age-dependent…”
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Detection of recombinant and endogenous mouse melatonin receptors by monoclonal antibodies targeting the C‐terminal domain
Published in Journal of pineal research (01-03-2019)“…Melatonin receptors play important roles in the regulation of circadian and seasonal rhythms, sleep, retinal functions, the immune system, depression, and type…”
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GPR50 in TGFβ signaling and breast cancer
Published in Oncoscience (27-06-2018)Get full text
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Melatonin membrane receptor type MT1 modulates cell-mediated immunity in the seasonally breeding tropical rodent Funambulus pennanti
Published in Neuroimmunomodulation (01-01-2012)“…Despite the evidence for melatonin membrane receptors (MT1R and MT2R) on lymphoid tissues in a wide range of seasonal breeders, their specific potency has…”
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