Pulmonary hyalinizing granuloma. Bilateral pulmonary nodules associated with chronic idiopathic thrombocytopenic purpura

Pulmonary hyalinizing granuloma. Bilateral pulmonary nodules associated with chronic idiopathic thrombocytopenic purpura

We report a case of a 30-year-old female who had been treated periodically with steroids for idiopathic thrombocytopenic purpura ITP over the last 10 years. Recently, during the course of investigation, she was found to have incidental asymptomatic multiple pulmonary nodules on chest CT. Following a...

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Bibliographic Details
Published in:Saudi medical journal Vol. 26; no. 9; p. 1459
Main Authors: Satti, Mohamed B, Batouk, Abdelnasir A, Abdelaziz, Muntasir M, Ahmad, Mohamed F, Abdelaal, Mohamed A
Format: Journal Article
Language:English
Published: Saudi Arabia 01-09-2005
Subjects:
Adult
Biopsy, Needle
Female
Follow-Up Studies
Granuloma, Respiratory Tract - complications
Granuloma, Respiratory Tract - diagnosis
Granuloma, Respiratory Tract - drug therapy
Humans
Hyalin - metabolism
Immunohistochemistry
Prednisolone - therapeutic use
Purpura, Thrombocytopenic, Idiopathic - complications
Purpura, Thrombocytopenic, Idiopathic - diagnosis
Purpura, Thrombocytopenic, Idiopathic - drug therapy
Rare Diseases
Risk Assessment
Tomography, X-Ray Computed
Treatment Outcome
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Summary:We report a case of a 30-year-old female who had been treated periodically with steroids for idiopathic thrombocytopenic purpura ITP over the last 10 years. Recently, during the course of investigation, she was found to have incidental asymptomatic multiple pulmonary nodules on chest CT. Following a needle biopsy to exclude malignancy, 2 nodules were excised and were histologically confirmed as pulmonary hyalinizing granuloma PHG. The remaining 2 nodules regressed on increasing her dose of steroids. The case is discussed with emphasis on the histological and radiological differential diagnosis, in addition to including ITP among the spectrum of immunologic conditions associated with PHG.
ISSN:0379-5284