Long COVID and Wavering Incidence of Pulmonary Embolism: A Systematic Review

Pulmonary embolism (PE) is a serious medical condition that can occur as a result of venous thromboembolism (VTE). COVID-19, also known as Post-Acute Sequelae of SARS-CoV-2 infection (PASC), can potentially lead to PE due to the formation of blood clots in the lungs. This study aims to collate and r...

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Bibliographic Details
Published in:	Journal of community hospital internal medicine perspectives Vol. 13; no. 5; pp. 23 - 31
Main Authors:	Shah, Bushra, Ahmad, Mah Noor, Khalid, Musfira, Minhas, Amna, Ali, Ramsha, Sarfraz, Zouina, Sarfraz, Azza
Format:	Journal Article
Language:	English
Published:	United States Greater Baltimore Medical Center 02-09-2023
Subjects:	Review Pulmonary embolism SARS-CoV-2 Post-COVID-19 syndrome Long COVID Thromboembolic disorder
Online Access:	Get full text
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Summary:	Pulmonary embolism (PE) is a serious medical condition that can occur as a result of venous thromboembolism (VTE). COVID-19, also known as Post-Acute Sequelae of SARS-CoV-2 infection (PASC), can potentially lead to PE due to the formation of blood clots in the lungs. This study aims to collate and report trends of PE in patients with long COVID (4-12 weeks since infection) and post-COVID-19 syndrome (>12 weeks since infection). The study adhered to PRISMA Statement 2020 guidelines, and a systematic search was conducted in four databases. In total, nine observational studies were included with a total patient count of 45,825,187. The incidence of PE with long COVID/post-COVID-19 syndrome was seen among 31,885 individuals out of 44,967,887 participants. The incidence rate of PE was observed as 0.07%, given that the studies included matched controls. While we cannot state with certainty that COVID-19 infection in itself leads to higher risks of PE at a later time, this study emphasizes the need for optimized care and longitudinal studies during the COVID-19 era to account for deviations from the norm.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 ObjectType-Review-3 content type line 23
ISSN:	2000-9666 2000-9666
DOI:	10.55729/2000-9666.1233