Search Results - "Ahmad, Kareem"
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Probing the limits of aptamer affinity with a microfluidic SELEX platform
Published in PloS one (14-11-2011)“…Nucleic acid-based aptamers offer many potential advantages relative to antibodies and other protein-based affinity reagents, including facile chemical…”
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Selection is more intelligent than design: improving the affinity of a bivalent ligand through directed evolution
Published in Nucleic acids research (01-12-2012)“…Multivalent molecular interactions can be exploited to dramatically enhance the performance of an affinity reagent. The enhancement in affinity and specificity…”
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Outcomes of mechanically ventilated patients with COVID-19 associated respiratory failure
Published in PloS one (23-11-2020)“…The outcomes of patients requiring invasive mechanical ventilation for COVID-19 remain poorly defined. We sought to determine clinical characteristics and…”
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Modeling Human Neurological and Neurodegenerative Diseases: From Induced Pluripotent Stem Cells to Neuronal Differentiation and Its Applications in Neurotrauma
Published in Frontiers in molecular neuroscience (28-02-2017)“…With the help of several inducing factors, somatic cells can be reprogrammed to become induced pluripotent stem cell (iPSCs) lines. The success is in obtaining…”
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Development of an efficient targeted cell-SELEX procedure for DNA aptamer reagents
Published in PloS one (13-08-2013)“…DNA aptamers generated by cell-SELEX offer an attractive alternative to antibodies, but generating aptamers to specific, known membrane protein targets has…”
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Transformation of Personal Computers and Mobile Phones into Genetic Diagnostic Systems
Published in Analytical chemistry (Washington) (16-09-2014)“…Molecular diagnostics based on the polymerase chain reaction (PCR) offer rapid and sensitive means for detecting infectious disease, but prohibitive costs have…”
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Connective tissue disease-associated interstitial lung disease and outcomes after hospitalization: A cohort study
Published in Respiratory medicine (01-07-2019)“…The impact of hospitalization on patient outcomes is increasingly recognized and considered in the prognostication of many pulmonary disorders. We sought to…”
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Idiopathic pulmonary fibrosis patients with severe physiologic impairment: characteristics and outcomes
Published in Respiratory research (06-01-2021)“…There is no widely accepted grading system for IPF disease severity, although physiologic impairment based on pulmonary function testing is frequently…”
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Review of Recent Efforts in Cooling Photovoltaic Panels (PVs) for Enhanced Performance and Better Impact on the Environment
Published in Nanomaterials (Basel, Switzerland) (13-05-2022)“…The global need for energy has grown in tandem with mankind's development and spread. This has resulted in an increase in the use of fossil energy sources, a…”
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Nitrous Oxide Induces Prominent Cell Proliferation in Adult Rat Hippocampal Dentate Gyrus
Published in Frontiers in cellular neuroscience (17-05-2018)“…The identification of distinct and more efficacious antidepressant treatments is highly needed. Nitrous oxide (N O) is an N-methyl-D-aspartic acid (NMDA)…”
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Improving Aptamer Selection Efficiency through Volume Dilution, Magnetic Concentration, and Continuous Washing in Microfluidic Channels
Published in Analytical chemistry (Washington) (01-09-2011)“…The generation of nucleic acid aptamers with high affinity typically entails a time-consuming, iterative process of binding, separation, and amplification. It…”
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Selection Strategy to Generate Aptamer Pairs that Bind to Distinct Sites on Protein Targets
Published in Analytical chemistry (Washington) (19-06-2012)“…Many analytical techniques benefit greatly from the use of affinity reagent pairs, wherein each reagent recognizes a discrete binding site on a target. For…”
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Evaluating parental experiences in teaching children with learning disabilities in resource rooms of public schools in Amman
Published in Frontiers in education (Lausanne) (29-10-2024)“…Background The education of children with learning disabilities in public schools’ resource rooms remains a vital area of concern, particularly in Amman, where…”
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The role of public school principals and teachers in developing the social responsibility of students with learning disabilities: a joint perspective
Published in Frontiers in education (Lausanne) (28-10-2024)“…Introduction Public school principals and teachers are crucial in shaping students with learning disabilities to become socially responsible individuals…”
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Chemosensitivity of U251 Cells to the Co-treatment of D-Penicillamine and Copper: Possible Implications on Wilson Disease Patients
Published in Frontiers in molecular neuroscience (31-01-2017)“…D-Penicillamine (PA), a copper chelator, and one of the recommended drugs for treatment of Wilson disease (WD) has been reported to worsen the symptoms of…”
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HRCT evaluation of patients with interstitial lung disease: comparison of the 2018 and 2011 diagnostic guidelines
Published in Therapeutic advances in respiratory disease (2020)“…Background and aims: Chest high-resolution computed tomography (HRCT) is the central diagnostic tool in discerning idiopathic pulmonary fibrosis (IPF) from…”
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Rathke cleft cyst with size fluctuation: A systematic literature review and case illustration
Published in Interdisciplinary neurosurgery : Advanced techniques and case management (01-09-2021)“…Rathke cleft cysts (RCCs) are known sellar/suprasellar lesions that can grow and become symptomatic. For most asymptomatic lesions, stability is a typical…”
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The Use of 5-Aminolevulinic Acid in Low-Grade Glioma Resection: A Systematic Review
Published in Operative neurosurgery (Hagerstown, Md.) (01-07-2020)“…Abstract BACKGROUND For optimizing high-grade glioma resection, 5-aminolevulinic acid is a reliable tool. However, its efficacy in low-grade glioma resection…”
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Inhaled Nitric Oxide via High-Flow Nasal Cannula in Patients with Acute Respiratory Failure Related to COVID-19
Published in Clinical medicine insights. Circulatory, respiratory and pulmonary medicine (2021)“…INTRODUCTION Limited evidence exists regarding use of inhaled nitric oxide (iNO) in spontaneously breathing patients. We evaluated the effectiveness of…”
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Endovascular Embolization of a Lateral Sacral Fistula: 2-Dimensional Operative Video
Published in Operative neurosurgery (Hagerstown, Md.) (01-09-2020)“…Abstract Spinal dural arteriovenous fistulas are the most common vascular malformations of the spine. They are localized in the sacral spine in 5% to 14% of…”
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