Search Results - "Ahmad, Haslina"
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Progress in Mesoporous Silica Nanoparticles as Drug Delivery Agents for Cancer Treatment
Published in Pharmaceutics (24-01-2021)“…Cancer treatment and therapy have made significant leaps and bounds in these past decades. However, there are still cases where surgical removal is impossible,…”
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Functionalized mesoporous silica nanoparticles templated by pyridinium ionic liquid for hydrophilic and hydrophobic drug release application
Published in Journal of Saudi Chemical Society (01-03-2020)“…Chemotherapy is the most common treatment for all cancer patients but this treatment poses many side effects due to lack of drug’s selectivity. To overcome…”
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Synergy of ruthenium metallo-intercalator, [Ru(dppz)2(PIP)]2+, with PARP inhibitor Olaparib in non-small cell lung cancer cells
Published in Scientific reports (26-01-2023)“…Poly(ADP-ribose) polymerase (PARP) are critical DNA repair enzymes that are activated as part of the DNA damage response (DDR). Although inhibitors of PARP…”
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A Kinetic Approach of DPPH Free Radical Assay of Ferulate-Based Protic Ionic Liquids (PILs)
Published in Molecules (Basel, Switzerland) (05-12-2018)“…The antiradical efficiency (AE) and kinetic behavior of a new ferulate-based protic ionic liquids (PILs) were described using 2,2-diphenyl-1-picrylhydrazyl…”
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Synthesis and Optimization of Mesoporous Silica Nanoparticles for Ruthenium Polypyridyl Drug Delivery
Published in Pharmaceutics (24-01-2021)“…The ruthenium polypyridyl complex [Ru(dppz) PIP] (dppz: dipyridophenazine, PIP: (2-(phenyl)-imidazo[4,5-f ][1,10]phenanthroline), or Ru-PIP, is a potential…”
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Efficient removal of pharmaceuticals from water using graphene nanoplatelets as adsorbent
Published in Royal Society open science (01-01-2021)“…Recently, pharmaceutical pollutants in water have emerged as a global concern as they give threat to human health and the environment. In this study, graphene…”
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Synthesis, characterization and biological evaluation of transition metal complexes derived from N, S bidentate ligands
Published in International journal of molecular sciences (15-05-2015)“…Two bidentate NS ligands were synthesized by the condensation reaction of S-2-methylbenzyldithiocarbazate (S2MBDTC) with 2-methoxybenzaldehyde (2MB) and…”
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The Therapeutic Effect and In Vivo Assessment of Palmitoyl-GDPH on the Wound Healing Process
Published in Pharmaceutics (01-02-2021)“…The standard treatment of open wounds via the direct usage of therapeutic agents is not without limitations with respect to healing. Small peptides can create…”
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Carbon (IV) oxide adsorption efficiency of functionalized HKUST-1, IRMF-1, and UiO-66 metal organic frameworks
Published in Journal of Nigerian Society of Physical Sciences (06-03-2024)“…The ever-increasing consumption of fossil fuels to meet up with the global economic and industrial energy needs has led to climatic change due to…”
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Discovery of bioactive peptides as therapeutic agents for skin wound repair
Published in Journal of tissue engineering (01-01-2024)“…Short sequences of amino acids called peptides have a wide range of biological functions and the potential to treat a number of diseases. Bioactive peptides…”
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Synthesis and in vitro biological evaluations of novel tetrapeptide as therapeutic agent for wound treatment
Published in Journal of Saudi Chemical Society (01-08-2020)“…We report a new small peptide containing four amino acid residues (glycine-aspartic acid-proline-histidine) conjugated with palmitic acid (Palmitoyl-GDPH) that…”
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Tuning the Excited State of Photoactive Building Blocks for Metal-Templated Self-Assembly
Published in Chemistry, an Asian journal (05-09-2011)“…The reaction of 2,2′:4,4′′:4′,4′′′‐quaterpyridyl (qtpy), with d6 ruthenium(II) (RuII), and rhenium(I) (ReI) metal centers has been investigated. The pendant…”
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Combining PARP Inhibition with Platinum, Ruthenium or Gold Complexes for Cancer Therapy
Published in ChemMedChem (18-11-2020)“…Platinum drugs are heavily used first‐line chemotherapeutic agents for many solid tumours and have stimulated substantial interest in the biological activity…”
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Potential of Phenylalanine‐, Tryptophan‐, and Tyrosine‐MOF‐5 Composites for Selective Carbon Dioxide and Methane Adsorption
Published in Macromolecular theory and simulations (26-07-2024)“…Abstract Metal‐organic frameworks (MOFs) have emerged as versatile materials with exceptional properties, including high porosities, large surface areas, and…”
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Binding of tetrabutylammonium bromide based deep eutectic solvent to DNA by spectroscopic analysis
Published in Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy (15-05-2021)“…[Display omitted] The binding characteristics of DNA in deep eutectic solvents (DESs), particularly the binding energy and interaction mechanism, are not…”
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Ruthenium(II) Polypyridyl Complexes as FRET Donors: Structure- and Sequence-Selective DNA-Binding and Anticancer Properties
Published in Journal of the American Chemical Society (18-01-2023)“…Ruthenium(II) polypyridyl complexes (RPCs) that emit from metal-to-ligand charge transfer (MLCT) states have been developed as DNA probes and are being…”
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Binding energy and biophysical properties of ionic liquid-DNA complex: Understanding the role of hydrophobic interactions
Published in Journal of molecular liquids (01-11-2016)“…The properties of DNA in ionic liquids (ILs) have been well studied. However, it is not widely known about the quantitative analysis of ILs such as the binding…”
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Using ancillary ligands to tune the DNA binding properties of self-assembled luminescent metallomacrocycles
Published in Chemical communications (Cambridge, England) (14-04-2014)“…The optical response, binding parameters, and duplex DNA binding mode of water-soluble kinetically inert tetranuclear metallomacrocycles can all be controlled…”
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Bio-nanogate manipulation on electrode surface as an electrochemical immunosensing strategy for detecting anti-hepatitis B surface antigen
Published in Bioelectrochemistry (Amsterdam, Netherlands) (01-02-2022)“…[Display omitted] •A proof-of-concept of a bio-nanogate-based immunosensor for anti-HBsAg was presented.•The binding of PAMAM-Au to MBP-aD was manipulated to…”
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A ruthenium polypyridyl intercalator stalls DNA replication forks, radiosensitizes human cancer cells and is enhanced by Chk1 inhibition
Published in Scientific reports (25-08-2016)“…Ruthenium(II) polypyridyl complexes can intercalate DNA with high affinity and prevent cell proliferation; however, the direct impact of ruthenium-based…”
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