Search Results - "Ahmad, Afza"
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Carvacrol Exhibits Chemopreventive Potential against Cervical Cancer Cells via Caspase-Dependent Apoptosis and Abrogation of Cell Cycle Progression
Published in Anti-cancer agents in medicinal chemistry (01-11-2021)“…The carcinogenesis of the uterine cervix is predominantly initiated with the consistent infection of the Human Papilloma Virus (HPV). Owing to the side effects…”
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Glycyrrhizin Mediates Downregulation of Notch Pathway Resulting in Initiation of Apoptosis and Disruption in the Cell Cycle Progression in Cervical Cancer Cells
Published in Nutrition and cancer (07-02-2022)“…Growing emphasis on exploring the antiproliferative potential of natural compounds has gathered momentum for the formulation of anticancer drugs. In the…”
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A Comprehensive Review on Cross-talk of Human Papilloma Virus Oncoproteins and Developmental/Self-Renewal Pathways During the Pathogenesis of Uterine Cervical Cancer
Published in Current molecular medicine (01-01-2021)“…Cervical cancer, cancer arising from the uterine cervix, has been regarded as the fourth most frequent gynecological malignancy among females worldwide…”
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4
Organosulphur Compounds Induce Apoptosis and Cell Cycle Arrest in Cervical Cancer Cells via Downregulation of HPV E6 and E7 Oncogenes
Published in Anti-cancer agents in medicinal chemistry (01-01-2021)“…The quest for strong, safe and cost-effective natural antiproliferative agents that could reduce cancer has been the focus now a days. In this regard, the…”
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5
Doxorubicin-Conjugated Zinc Oxide Nanoparticles, Biogenically Synthesised Using a Fungus Aspergillus niger , Exhibit High Therapeutic Efficacy against Lung Cancer Cells
Published in Molecules (Basel, Switzerland) (18-04-2022)“…This study reports the therapeutic effectiveness of doxorubicin-conjugated zinc oxide nanoparticles against lung cancer cell line. The zinc oxide nanoparticles…”
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Corrigendum: Methotrexate-conjugated zinc oxide nanoparticles exert substantially improved cytotoxic effect on lung cancer cells by inducing apoptosis
Published in Frontiers in pharmacology (29-07-2024)“…[This corrects the article DOI: 10.3389/fphar.2023.1194578.]…”
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Methotrexate-conjugated zinc oxide nanoparticles exert a substantially improved cytotoxic effect on lung cancer cells by inducing apoptosis
Published in Frontiers in pharmacology (17-10-2023)“…In the current study, we report the synthesis of methotrexate-conjugated zinc oxide nanoparticles (MTX-ZnONPs) and their high efficacy against lung cancer…”
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In Vitro Evaluation of Antioxidant, Anticancer, and Anti-Inflammatory Activities of Ethanolic Leaf Extract of Adenium obesum
Published in Frontiers in pharmacology (19-07-2022)“…Adenium obesum commonly known as “desert rose” belongs to the family Apopcynaceae and has previously been reported for its anti-influenza, antimicrobial, and…”
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Carvacrol instigates intrinsic and extrinsic apoptosis with abrogation of cell cycle progression in cervical cancer cells: Inhibition of Hedgehog/GLI signaling cascade
Published in Frontiers in chemistry (11-01-2023)“…Recent times have seen a strong surge in therapeutically targeting the hedgehog (HH)/GLI signaling pathway in cervical cancer. HH signaling pathway is reported…”
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Ethanolic Extract of Artemisia vulgaris Leaf Promotes Apoptotic Cell Death in Non-Small-Cell Lung Carcinoma A549 Cells through Inhibition of the Wnt Signaling Pathway
Published in Metabolites (27-03-2023)“…The Wnt signaling pathway is reported to be associated with lung cancer progression, metastasis and drug resistance, and thus it is an important therapeutic…”
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11
Molecular insights on chemopreventive and anticancer potential of carvacrol: Implications from solid carcinomas
Published in Journal of food biochemistry (01-12-2021)“…Globally, cancer is one of the deadliest diseases, estimated to cause 9.9 million deaths in 2020. Conventional cancer treatments commonly involve…”
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Emerging trends in gastrointestinal cancers: Targeting developmental pathways in carcinogenesis and tumor progression
Published in International review of cell and molecular biology (2024)“…Gastrointestinal carcinomas are a group of cancers associated with the digestive system and its accessory organs. The most prevalent cancers related to the…”
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Revisiting the Antiviral Efficacy of Terpenoids: Plausible Adjunct Therapeutics for Novel SARS-CoV-2?
Published in Endocrine, metabolic & immune disorders drug targets (2021)“…Presently the world is witnessing the most devastating pandemic in the history of mankind caused by Severe Acute Respiratory Syndrome or SARS-CoV-2. This…”
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14
High therapeutic efficacy of 5‐Fluorouracil‐loaded exosomes against colon cancer cells
Published in Chemical biology & drug design (01-04-2023)“…The successful chemotherapeutic regime required for the clinical management of different cancers largely depends on the efficient drug delivery within the…”
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Pinostrobin suppresses the proliferation of lung carcinoma cells by abrogating the cell cycle progression through the inhibition of Notch signaling pathway
Published in South African journal of botany (01-12-2022)“…•Pinostrobin (PN) suppressed the growth and proliferation of lung cancer cells (A549).•PN induced apoptosis via intrinsic apoptosis pathway.•PN abrogated the…”
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Ethanolic extract of Coleus aromaticus leaves impedes the proliferation and instigates apoptotic cell death in liver cancer HepG2 cells through repressing JAK/STAT cascade
Published in Journal of food biochemistry (01-10-2022)“…Liver cancer or hepatocellular carcinoma (HCC) has become a leading cause for cancer burden across the globe, and incidences have tripled since the last two…”
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Swertia chirayita suppresses the growth of non-small cell lung cancer A549 cells and concomitantly induces apoptosis via downregulation of JAK1/STAT3 pathway
Published in Saudi journal of biological sciences (01-11-2021)“…Lung carcinoma is the leading cause of cancer-related mortalities worldwide, and present therapeutical interventions are not successful enough to treat this…”
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18
Ethanolic Extract of IArtemisia vulgaris/I Leaf Promotes Apoptotic Cell Death in Non-Small-Cell Lung Carcinoma A549 Cells through Inhibition of the Wnt Signaling Pathway
Published in Metabolites (01-03-2023)“…The Wnt signaling pathway is reported to be associated with lung cancer progression, metastasis and drug resistance, and thus it is an important therapeutic…”
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19
Antiproliferative and apoptotic potential of Glycyrrhizin against HPV16+ Caski cervical cancer cells: A plausible association with downreguation of HPV E6 and E7 oncogenes and Notch signaling pathway
Published in Saudi journal of biological sciences (01-05-2022)“…Cervical cancer (CCa) is the second most frequent carcinoma in females and human papilloma virus (HPV) oncoproteins are regarded as one of the critical…”
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