Search Results - "Ahlskog, J."
-
1
Aerobic Exercise: Evidence for a Direct Brain Effect to Slow Parkinson Disease Progression
Published in Mayo Clinic proceedings (01-03-2018)“…No medications are proven to slow the progression of Parkinson disease (PD). Of special concern with longer-standing PD is cognitive decline, as well as motor…”
Get full text
Journal Article -
2
Does vigorous exercise have a neuroprotective effect in Parkinson disease?
Published in Neurology (19-07-2011)“…Parkinson disease (PD) is progressive, with dementia and medication-refractory motor problems common reasons for late-stage nursing-home placement. Increasing…”
Get full text
Journal Article -
3
Parkinson's disease progression is multifaceted: Evidence for the underlying benchmarks
Published in Parkinsonism & related disorders (01-04-2024)“…Long-term Parkinson's disease (PD) progression is not a homogeneous process and manifests in diverse ways over the lifetime. Recognition of progression…”
Get full text
Journal Article -
4
Time Trends in the Incidence of Parkinson Disease
Published in JAMA neurology (01-08-2016)“…Changes over time in the incidence of parkinsonism and Parkinson disease (PD) remain uncertain. To investigate secular trends (period effects) and birth cohort…”
Get more information
Journal Article -
5
Levodopa, homocysteine and Parkinson's disease: What's the problem?
Published in Parkinsonism & related disorders (01-04-2023)“…Elevated circulating homocysteine levels have been associated with cognitive impairment and cardio-cerebro-vascular events. Levodopa treatment of Parkinson's…”
Get full text
Journal Article -
6
Physical Exercise as a Preventive or Disease-Modifying Treatment of Dementia and Brain Aging
Published in Mayo Clinic proceedings (01-09-2011)“…A rapidly growing literature strongly suggests that exercise, specifically aerobic exercise, may attenuate cognitive impairment and reduce dementia risk. We…”
Get full text
Journal Article -
7
Common Myths and Misconceptions That Sidetrack Parkinson Disease Treatment, to the Detriment of Patients
Published in Mayo Clinic proceedings (01-10-2020)“…Parkinson disease symptoms become apparent when there has been substantial loss of brain dopamine. That is the consequence of the slow progression of the Lewy…”
Get full text
Journal Article -
8
Considerations for trials of disease modifying treatments in Parkinson disease
Published in Neurology (17-03-2020)Get full text
Journal Article -
9
Medical records documentation of constipation preceding Parkinson disease: A case-control study
Published in Neurology (24-11-2009)“…Parkinson disease (PD) may affect the autonomic nervous system and may cause constipation; however, few studies have explored constipation preceding the motor…”
Get full text
Journal Article -
10
Hyperglycemic chorea/ballism ascertained over 15 years at a referral medical center
Published in Parkinsonism & related disorders (01-03-2018)“…To describe chorea/ballism triggered by a hyperglycemic event. We used the electronic records system at Mayo Clinic–Rochester to identify patients diagnosed…”
Get full text
Journal Article -
11
Increased risk of cognitive impairment or dementia in women who underwent oophorectomy before menopause
Published in Neurology (11-09-2007)“…There is increasing laboratory evidence for a neuroprotective effect of estrogen; however, the clinical and epidemiologic evidence remains limited and…”
Get full text
Journal Article -
12
Beating a dead horse : Dopamine and Parkinson disease
Published in Neurology (23-10-2007)“…Our collective thinking about Parkinson disease (PD) has been heavily influenced by the dramatic response to dopamine replacement therapy. For progress to…”
Get full text
Journal Article -
13
High School Football and Risk of Neurodegeneration: A Community-Based Study
Published in Mayo Clinic proceedings (01-04-2012)“…Abstract Objective To assess whether high school football played between 1946 and 1956, when headgear was less protective than today, was associated with…”
Get full text
Journal Article -
14
Incidence and pathology of synucleinopathies and tauopathies related to parkinsonism
Published in JAMA neurology (01-07-2013)“…The frequency and distribution of synucleinopathies and tauopathies manifesting with parkinsonism in the general population are poorly understood, thus…”
Get more information
Journal Article -
15
New and Appropriate Goals for Parkinson Disease Physical Therapy
Published in JAMA neurology (01-03-2016)Get more information
Journal Article -
16
My Treatment Approach to Multiple System Atrophy
Published in Mayo Clinic proceedings (01-03-2021)“…Multiple system atrophy (MSA) is a neurodegenerative disorder primarily characterized by autonomic failure plus parkinsonism or cerebellar ataxia. The…”
Get full text
Journal Article -
17
Frequency of levodopa-related dyskinesias and motor fluctuations as estimated from the cumulative literature
Published in Movement disorders (01-05-2001)“…There is no clear consensus regarding the frequency (and hence, the risk), of dyskinesias or motor fluctuations during chronic levodopa therapy for Parkinson's…”
Get full text
Journal Article -
18
A genomic pathway approach to a complex disease: axon guidance and Parkinson disease
Published in PLoS genetics (01-06-2007)“…While major inroads have been made in identifying the genetic causes of rare Mendelian disorders, little progress has been made in the discovery of common gene…”
Get full text
Journal Article -
19
Increased risk of parkinsonism in women who underwent oophorectomy before menopause
Published in Neurology (15-01-2008)“…There is increasing laboratory evidence for a neuroprotective effect of estrogen on the nigrostriatal pathway; however, the epidemiologic evidence remains…”
Get full text
Journal Article -
20
Sensitivity and Specificity of Diagnostic Criteria for Progressive Supranuclear Palsy
Published in Movement disorders (01-08-2019)“…Background In 2017, the International Parkinson and Movement Disorder Society put forward new clinical criteria for the diagnosis of PSP, recognizing diverse…”
Get full text
Journal Article