Search Results - "Ahlen, G."
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Long-term functional duration of immune responses to HCV NS3/4A induced by DNA vaccination
Published in Gene therapy (01-08-2014)“…We have investigated the ability of hepatitis C virus non-structural (NS) 3/4A-DNA-based vaccines to activate long-term cell-mediated immune responses in mice…”
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Identification of galactose-alpha-1,3-galactose in the gastrointestinal tract of the tick Ixode sricinus; possible relationship with red meat allergy
Published in Allergy (Copenhagen) (2013)“…Patients with IgE antibodies against the carbohydrate epitope galactose--1,3-galactose (-Gal) have reported severe allergic reactions after consumption of red…”
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HIgh efficiency protocol for lymphocytes gene modification by lentiviral vector within an automated closed system
Published in CYTOTHERAPY (01-05-2020)“…Gene therapy with genetically modified lymphocytes has been progressively entering in the clinical settings mainly as clinical trials and recently also with…”
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Codon optimization and mRNA amplification effectively enhances the immunogenicity of the hepatitis C virus nonstructural 3 4A gene
Published in Gene therapy (01-03-2004)“…We have recently shown that the NS3-based genetic immunogens should contain also hepatitis C virus (HCV) nonstructural (NS) 4A to utilize fully the…”
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Identification of galactose‐α‐1,3‐galactose in the gastrointestinal tract of the tick Ixodes ricinus; possible relationship with red meat allergy
Published in Allergy (Copenhagen) (01-04-2013)“…Patients with IgE antibodies against the carbohydrate epitope galactose‐α‐1,3‐galactose (α‐Gal) have reported severe allergic reactions after consumption of…”
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The hepatitis C virus and immune evasion:: nonstructural 3/4A transgenic mice are resistant to lethal tumour necrosis factor α mediated liver disease
Published in Gut (01-10-2006)Get full text
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681 HCV NS3/4A-MEDIATED CCL2 AND TNFA SECRETION INCREASE HEPATOCYTE SURVIVAL AND LIVER REGENERATION IN VIVO
Published in Journal of hepatology (2010)Get full text
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Nucleoside-Modified mRNA Vaccines Protect IFNAR -/- Mice against Crimean-Congo Hemorrhagic Fever Virus Infection
Published in Journal of virology (09-02-2022)“…Crimean-Congo hemorrhagic fever (CCHF), caused by Crimean-Congo hemorrhagic fever virus (CCHFV), is on the World Health Organizations' list of prioritized…”
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Phosphatidylinositol 4-Kinase III Alpha Governs Cytoskeletal Organization for Invasiveness of Liver Cancer Cells
Published in Gastroenterology (New York, N.Y. 1943) (01-08-2024)“…High expression of phosphatidylinositol 4-kinase III alpha (PI4KIIIα) correlates with poor survival rates in patients with hepatocellular carcinoma. In…”
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Prolonged Epidural Infusions of Ropivacaine (2 mg/mL) After Colonic Surgery: The Impact of Adding Fentanyl
Published in Anesthesia and analgesia (01-05-2001)“…We evaluated the safety and efficacy of a 72-h epidural infusion of ropivacaine and measured the impact of adding fentanyl 2 μg/mL to the required infusion…”
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ATMP development and pre-GMP environment in academia: a safety net for early cell and gene therapy development and manufacturing
Published in Immuno-oncology technology (01-12-2022)“…Advanced therapy medicinal products (ATMP) are medicines for human use that are based on genes, cells or tissues. Over the past years, an increasing number of…”
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A universal SARS‐CoV DNA vaccine inducing highly cross‐reactive neutralizing antibodies and T cells
Published in EMBO molecular medicine (10-10-2022)“…New variants in the SARS‐CoV‐2 pandemic are more contagious (Alpha/Delta), evade neutralizing antibodies (Beta), or both (Omicron). This poses a challenge in…”
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Cleavage of the IPS-1/Cardif/MAVS/VISA does not inhibit T cell-mediated elimination of hepatitis C virus non-structural 3/4A-expressing hepatocytes
Published in Gut (01-04-2009)“…Hepatitis C virus (HCV) effectively establishes persistent infection in human livers. The non-structural (NS) 3/4A complex participates in this process by…”
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P202 EVALUATION OF A HEPATITIS C VIRUS THERAPEUTIC VACCINE CANDIDATE IN WILDTYPE- AND HCV-TRANSGENIC MICE
Published in Journal of hepatology (01-04-2014)Get full text
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Relation between viral fitness and immune escape within the hepatitis C virus protease
Published in Gut (01-02-2006)“…Background: The hepatitis C virus (HCV) mutates within human leucocyte antigen (HLA) class I restricted immunodominant epitopes of the non-structural (NS) 3/4A…”
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Metabolic Perturbation Associated With COVID-19 Disease Severity and SARS-CoV-2 Replication
Published in Molecular & cellular proteomics (01-01-2021)“…Viruses hijack host metabolic pathways for their replicative advantage. In this study, using patient-derived multiomics data and in vitro infection assays, we…”
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Editorial: HBV—the naked truth?
Published in Alimentary pharmacology & therapeutics (01-10-2019)“…LINKED CONTENTThis article is linked to Jiang et al papers. To view these articles, visit https://doi.org/10.1111/apt.15381 and…”
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