Search Results - "Ahlen, G."

Long-term functional duration of immune responses to HCV NS3/4A induced by DNA vaccination by Ahlén, G, Holmström, F, Gibbs, A, Alheim, M, Frelin, L

“…We have investigated the ability of hepatitis C virus non-structural (NS) 3/4A-DNA-based vaccines to activate long-term cell-mediated immune responses in mice…”
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Identification of galactose-alpha-1,3-galactose in the gastrointestinal tract of the tick Ixode sricinus; possible relationship with red meat allergy by Hamsten, C., Starkhammar, M., Tran, T. A. T., Johansson, Magnus, Bengtsson, U., Ahlen, G., Sallberg, M., Gronlund, H., van Hage, M.

“…Patients with IgE antibodies against the carbohydrate epitope galactose--1,3-galactose (-Gal) have reported severe allergic reactions after consumption of red…”
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HIgh efficiency protocol for lymphocytes gene modification by lentiviral vector within an automated closed system by Silva, D.N., Chrobok, M., Healy, K., Maravelia, P., Ahlen, G., Pasetto, A., Sallberg, M.

“…Gene therapy with genetically modified lymphocytes has been progressively entering in the clinical settings mainly as clinical trials and recently also with…”
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Codon optimization and mRNA amplification effectively enhances the immunogenicity of the hepatitis C virus nonstructural 3 4A gene by FRELIN, L, AHLEN, G, ALHEIM, M, WEILAND, O, BARNFIELD, C, LILJESTRÖM, P, SÄLLBERG, M

“…We have recently shown that the NS3-based genetic immunogens should contain also hepatitis C virus (HCV) nonstructural (NS) 4A to utilize fully the…”
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320 THE HEPATITIS C VIRUS NON-STRUCTURAL 3/4A PROTEASE MEDIATES AN INTRAHEPATIC T HELPER(Th)-1 TO Th2 SHIFT BY CLEAVING THE T CELL PROTEIN TYROSINE PHOSPHATASE by Brenndörfer, E.D, Brass, A, Karthe, J, Ahlen, G, Bode, J.G, Sällberg, M

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843 A SYNTHETIC CODON-OPTIMIZED HCV NON-STRUCTURAL 5A DNA VACCINE PRIMES POLYFUNCTIONAL CD8+ T CELL RESPONSES IN WILDTYPE AND NS5A-TRANSGENIC MICE by Holmstrom, F, Kriegs, M, Hildt, E, Sallberg, M, Ahlen, G, Frelin, L

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Identification of galactose‐α‐1,3‐galactose in the gastrointestinal tract of the tick Ixodes ricinus; possible relationship with red meat allergy by Hamsten, C., Starkhammar, M., Tran, T. A. T., Johansson, M., Bengtsson, U., Ahlén, G., Sällberg, M., Grönlund, H., Hage, M.

“…Patients with IgE antibodies against the carbohydrate epitope galactose‐α‐1,3‐galactose (α‐Gal) have reported severe allergic reactions after consumption of…”
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The hepatitis C virus and immune evasion:: nonstructural 3/4A transgenic mice are resistant to lethal tumour necrosis factor α mediated liver disease by Frelin, L, Brenndorfer, ED, Ahlen, G, Weiland, M, Hultgren, C, Alheim, M, Glaumann, H, Rozell, B, Milich, DR, Bode, JG

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681 HCV NS3/4A-MEDIATED CCL2 AND TNFA SECRETION INCREASE HEPATOCYTE SURVIVAL AND LIVER REGENERATION IN VIVO by Brenndörfer, E.D, Weiland, M, Frelin, L, Derk, E, Ahlen, G, Bode, J.G, Sällberg, M

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Nucleoside-Modified mRNA Vaccines Protect IFNAR -/- Mice against Crimean-Congo Hemorrhagic Fever Virus Infection by Appelberg, Sofia, John, Lijo, Pardi, Norbert, Végvári, Ákos, Bereczky, Sándor, Ahlén, Gustaf, Monteil, Vanessa, Abdurahman, Samir, Mikaeloff, Flora, Beattie, Mitchell, Tam, Ying, Sällberg, Matti, Neogi, Ujjwal, Weissman, Drew, Mirazimi, Ali

“…Crimean-Congo hemorrhagic fever (CCHF), caused by Crimean-Congo hemorrhagic fever virus (CCHFV), is on the World Health Organizations' list of prioritized…”
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Phosphatidylinositol 4-Kinase III Alpha Governs Cytoskeletal Organization for Invasiveness of Liver Cancer Cells by Tran, Cong Si, Kersten, Julia, Yan, Jingyi, Breinig, Marco, Huth, Thorben, Poth, Tanja, Colasanti, Ombretta, Riedl, Tobias, Faure-Dupuy, Suzanne, Diehl, Stefan, Verhoye, Lieven, Li, Teng-Feng, Lingemann, Marit, Schult, Philipp, Ahlén, Gustaf, Frelin, Lars, Kühnel, Florian, Vondran, Florian W.R., Breuhahn, Kai, Meuleman, Philip, Heikenwälder, Mathias, Schirmacher, Peter, Bartenschlager, Ralf, Laketa, Vibor, Roessler, Stephanie, Tschaharganeh, Darjus Felix, Sällberg, Matti, Lohmann, Volker

“…High expression of phosphatidylinositol 4-kinase III alpha (PI4KIIIα) correlates with poor survival rates in patients with hepatocellular carcinoma. In…”
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Prolonged Epidural Infusions of Ropivacaine (2 mg/mL) After Colonic Surgery: The Impact of Adding Fentanyl by Finucane, Brendan T., Ganapathy, Sugantha, Carli, Francesco, Pridham, Jeremy N., Ong, Bill Y., Shukla, Romesh C., Kristoffersson, Ann H. M., Huizar, Karin M., Nevin, Krista, Ahlén, Kjell G.

“…We evaluated the safety and efficacy of a 72-h epidural infusion of ropivacaine and measured the impact of adding fentanyl 2 μg/mL to the required infusion…”
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ATMP development and pre-GMP environment in academia: a safety net for early cell and gene therapy development and manufacturing by Silva, D.N., Chrobok, M., Ahlén, G., Blomberg, P., Sällberg, M., Pasetto, A.

“…Advanced therapy medicinal products (ATMP) are medicines for human use that are based on genes, cells or tissues. Over the past years, an increasing number of…”
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A universal SARS‐CoV DNA vaccine inducing highly cross‐reactive neutralizing antibodies and T cells by Appelberg, Sofia, Ahlén, Gustaf, Yan, Jingyi, Nikouyan, Negin, Weber, Sofie, Larsson, Olivia, Höglund, Urban, Aleman, Soo, Weber, Friedemann, Perlhamre, Emma, Apro, Johanna, Gidlund, Eva‐Karin, Tuvesson, Ola, Salati, Simona, Cadossi, Matteo, Tegel, Hanna, Hober, Sophia, Frelin, Lars, Mirazimi, Ali, Sällberg, Matti

“…New variants in the SARS‐CoV‐2 pandemic are more contagious (Alpha/Delta), evade neutralizing antibodies (Beta), or both (Omicron). This poses a challenge in…”
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Cleavage of the IPS-1/Cardif/MAVS/VISA does not inhibit T cell-mediated elimination of hepatitis C virus non-structural 3/4A-expressing hepatocytes by Ahlén, G, Derk, E, Weiland, M, Jiao, J, Rahbin, N, Aleman, S, Peterson, D L, Pokrovskaja, K, Grandér, D, Frelin, L, Sällberg, M

“…Hepatitis C virus (HCV) effectively establishes persistent infection in human livers. The non-structural (NS) 3/4A complex participates in this process by…”
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P183 A THERAPEUTIC VACCINE BASED ON THE HEPATITIS B CORE ANTIGEN IN COMBINATION WITH INTERLEUKIN-12 EFFECTIVELY INDUCES IMMUNE RESPONSES IN HBV-TRANSGENIC MICE by Brass, A, Frelin, L, Sällberg, M, Ahlén, G

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P202 EVALUATION OF A HEPATITIS C VIRUS THERAPEUTIC VACCINE CANDIDATE IN WILDTYPE- AND HCV-TRANSGENIC MICE by Holmström, F, Sällberg, M, Ahlén, G, Frelin, L

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Relation between viral fitness and immune escape within the hepatitis C virus protease by Söderholm, J, Ahlén, G, Kaul, A, Frelin, L, Alheim, M, Barnfield, C, Liljeström, P, Weiland, O, Milich, D R, Bartenschlager, R, Sällberg, M

“…Background: The hepatitis C virus (HCV) mutates within human leucocyte antigen (HLA) class I restricted immunodominant epitopes of the non-structural (NS) 3/4A…”
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Metabolic Perturbation Associated With COVID-19 Disease Severity and SARS-CoV-2 Replication by Krishnan, Shuba, Nordqvist, Hampus, Ambikan, Anoop T., Gupta, Soham, Sperk, Maike, Svensson-Akusjärvi, Sara, Mikaeloff, Flora, Benfeitas, Rui, Saccon, Elisa, Ponnan, Sivasankaran Munusamy, Rodriguez, Jimmy Esneider, Nikouyan, Negin, Odeh, Amani, Ahlén, Gustaf, Asghar, Muhammad, Sällberg, Matti, Vesterbacka, Jan, Nowak, Piotr, Végvári, Ákos, Sönnerborg, Anders, Treutiger, Carl Johan, Neogi, Ujjwal

“…Viruses hijack host metabolic pathways for their replicative advantage. In this study, using patient-derived multiomics data and in vitro infection assays, we…”
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Editorial: HBV—the naked truth? by Pasetto, Anna, Ahlén, Gustaf, Sällberg, Matti

“…LINKED CONTENTThis article is linked to Jiang et al papers. To view these articles, visit https://doi.org/10.1111/apt.15381 and…”
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