Search Results - "Aherrahrou, R."

Genome-wide analysis identifies novel susceptibility loci for myocardial infarction by Hartiala, Jaana A, Han, Yi, Jia, Qiong, Hilser, James R, Huang, Pin, Gukasyan, Janet, Schwartzman, William S, Cai, Zhiheng, Biswas, Subarna, Trégouët, David-Alexandre, Smith, Nicholas L, Seldin, Marcus, Pan, Calvin, Mehrabian, Margarete, Lusis, Aldons J, Bazeley, Peter, Sun, Yan V, Liu, Chang, Quyyumi, Arshed A, Scholz, Markus, Thiery, Joachim, Delgado, Graciela E, Kleber, Marcus E, März, Winfried, Howe, Laurence J, Asselbergs, Folkert W, van Vugt, Marion, Vlachojannis, Georgios J, Patel, Riyaz S, Lyytikäinen, Leo-Pekka, Kähönen, Mika, Lehtimäki, Terho, Nieminen, Tuomo V M, Kuukasjärvi, Pekka, Laurikka, Jari O, Chang, Xuling, Heng, Chew-Kiat, Jiang, Rong, Kraus, William E, Hauser, Elizabeth R, Ferguson, Jane F, Reilly, Muredach P, Ito, Kaoru, Koyama, Satoshi, Kamatani, Yoichiro, Komuro, Issei, Stolze, Lindsey K, Romanoski, Casey E, Khan, Mohammad Daud, Turner, Adam W, Miller, Clint L, Aherrahrou, Redouane, Civelek, Mete, Ma, Lijiang, Björkegren, Johan L M, Kumar, S Ram, Tang, W H Wilson, Hazen, Stanley L, Allayee, Hooman

“…While most patients with myocardial infarction (MI) have underlying coronary atherosclerosis, not all patients with coronary artery disease (CAD) develop MI…”
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Functional Characterization of the GUCY1A3 Coronary Artery Disease Risk Locus by Kessler, Thorsten, Wobst, Jana, Wolf, Bernhard, Eckhold, Juliane, Vilne, Baiba, Hollstein, Ronja, von Ameln, Simon, Dang, Tan An, Sager, Hendrik B, Moritz Rumpf, Philipp, Aherrahrou, Redouane, Kastrati, Adnan, Björkegren, Johan L.M, Erdmann, Jeanette, Lusis, Aldons J, Civelek, Mete, Kaiser, Frank J, Schunkert, Heribert

“…BACKGROUND:A chromosomal locus at 4q32.1 has been genome-wide significantly associated with coronary artery disease risk. The locus encompasses GUCY1A3, which…”
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Functional fine-mapping of coronary artery disease risk variants identified by single-cell profiling of accessible chromatin in human atherosclerotic lesions by Örd, T., Õunap, K., Stolze, L.K., Nurminen, V., Aherrahrou, R., Toropainen, A., Aavik, E., Ylä-Herttuala, S., Civelek, M., Romanoski, C.E., Kaikkonen, M.U.

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Genetic Regulation of Atherosclerosis-Relevant Phenotypes in Human Vascular Smooth Muscle Cells by Aherrahrou, Redouane, Guo, Liang, Nagraj, V. Peter, Aguhob, Aaron, Hinkle, Jameson, Chen, Lisa, Yuhl Soh, Joon, Lue, Dillon, Alencar, Gabriel F., Boltjes, Arjan, van der Laan, Sander W., Farber, Emily, Fuller, Daniela, Anane-Wae, Rita, Akingbesote, Ngozi, Manichaikul, Ani W., Ma, Lijiang, Kaikkonen, Minna U., Björkegren, Johan L.M., Önengüt-Gümüşcü, Suna, Pasterkamp, Gerard, Miller, Clint L., Owens, Gary K., Finn, Aloke, Navab, Mohamad, Fogelman, Alan M., Berliner, Judith A., Civelek, Mete

“…RATIONALE:Coronary artery disease (CAD) is a major cause of morbidity and mortality worldwide. Recent genome-wide association studies revealed 163 loci…”
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Genetic Regulation of SMC Gene Expression and Splicing Predict Causal CAD Genes by Aherrahrou, Rédouane, Lue, Dillon, Perry, R. Noah, Aberra, Yonathan Tamrat, Khan, Mohammad Daud, Soh, Joon Yuhl, Örd, Tiit, Singha, Prosanta, Yang, Qianyi, Gilani, Huda, Benavente, Ernest Diez, Wong, Doris, Hinkle, Jameson, Ma, Lijiang, Sheynkman, Gloria M., den Ruijter, Hester M., Miller, Clint L., Björkegren, Johan L.M., Kaikkonen, Minna U., Civelek, Mete

“…Coronary artery disease (CAD) is the leading cause of death worldwide. Recent meta-analyses of genome-wide association studies have identified over 175 loci…”
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Female Gene Networks Are Expressed in Myofibroblast-Like Smooth Muscle Cells in Vulnerable Atherosclerotic Plaques by Diez Benavente, Ernest, Karnewar, Santosh, Buono, Michele, Mili, Eloi, Hartman, Robin J G, Kapteijn, Daniek, Slenders, Lotte, Daniels, Mark, Aherrahrou, Redouane, Reinberger, Tobias, Mol, Barend M, de Borst, Gert J, de Kleijn, Dominique P V, Prange, Koen H M, Depuydt, Marie A C, de Winther, Menno P J, Kuiper, Johan, Björkegren, Johan L M, Erdmann, Jeanette, Civelek, Mete, Mokry, Michal, Owens, Gary K, Pasterkamp, Gerard, den Ruijter, Hester M

“…Women presenting with coronary artery disease more often present with fibrous atherosclerotic plaques, which are currently understudied. Phenotypically…”
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FHL5 Controls Vascular Disease–Associated Gene Programs in Smooth Muscle Cells by Wong, Doris, Auguste, Gaëlle, Lino Cardenas, Christian L., Turner, Adam W., Chen, Yixuan, Song, Yipei, Ma, Lijiang, Perry, R. Noah, Aherrahrou, Redouane, Kuppusamy, Maniselvan, Yang, Chaojie, Mosquera, Jose Verdezoto, Dube, Collin J., Khan, Mohammad Daud, Palmore, Meredith, Kalra, Jaspreet, Kavousi, Maryam, Peyser, Patricia A., Matic, Ljubica, Hedin, Ulf, Manichaikul, Ani, Sonkusare, Swapnil K., Civelek, Mete, Kovacic, Jason C., Björkegren, Johan L.M., Malhotra, Rajeev, Miller, Clint L.

“…Genome-wide association studies have identified hundreds of loci associated with common vascular diseases, such as coronary artery disease, myocardial…”
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Single-Cell Gene-Regulatory Networks of Advanced Symptomatic Atherosclerosis by Mocci, Giuseppe, Sukhavasi, Katyayani, Örd, Tiit, Bankier, Sean, Singha, Prosanta, Arasu, Uma Thanigai, Agbabiaje, Olayinka Oluwasegun, Mäkinen, Petri, Ma, Lijiang, Hodonsky, Chani J, Aherrahrou, Redouane, Muhl, Lars, Liu, Jianping, Gustafsson, Sonja, Byandelger, Byambajav, Wang, Ying, Koplev, Simon, Lendahl, Urban, Owens, Gary K, Leeper, Nicholas J, Pasterkamp, Gerard, Vanlandewijck, Michael, Michoel, Tom, Ruusalepp, Arno, Hao, Ke, Ylä-Herttuala, Seppo, Väli, Marika, Järve, Heli, Mokry, Michal, Civelek, Mete, Miller, Clint J, Kovacic, Jason C, Kaikkonen, Minna U, Betsholtz, Christer, Björkegren, Johan L M

“…While our understanding of the single-cell gene expression patterns underlying the transformation of vascular cell types during the progression of…”
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Identification of a single SNP that affects the LH-beta promoter activity in the Moroccan prolific D'man breed1 by Aherrahrou, R., Aherrahrou, Z., Kaiser, F. J., Braunholz, D., Erdmann, J., Moumni, M.

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Identification of a single SNP that affects the LH-beta promoter activity in the Moroccan prolific D'man breed 1 by Aherrahrou, R, Aherrahrou, Z, Kaiser, F J, Braunholz, D, Erdmann, J, Moumni, M

“…Common Moroccan breeds D'man, Sardi, and Timahdite have been found to differ regarding litter size. D'man is known for its high prolificacy (2-7 lambs),…”
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P4471The 4q32.1 coronary artery disease locus influences disease risk via differential transcription factor binding by Kessler, T., Wobst, J., Wolf, B., Eckhold, J., Vilne, B., Hollstein, R., Sager, H.B., Aherrahrou, R., Kastrati, A., Bjoerkegren, J.L.M., Erdmann, J., Lusis, A.J., Civelek, M., Kaiser, F.J., Schunkert, H.

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Genetic Regulation of Atherosclerosis-relevant Phenotypes in Human Vascular Smooth Muscle Cells by Aherrahrou, R, Guo, L, Nagraj, V, Aguhob, AA, Hinkle, J, Chen, L, Soh, JY, Lue, D, Alencar, G, Boltjes, A, van der Laan, SW, Farber, E, Fuller, D, Wae, RA, Akingbesote, N, Ma, LJ, Bjorkegren, J, Onengut-Gumuscu, S, Pasterkamp, G, Miller, C, Owens, GK, Finn, A, Navab, M, Civelek, M

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Identification of a single SNP that affects the promoter activity in the Moroccan prolific D'man breed by Aherrahrou, R, Aherrahrou, Z, Kaiser, F J, Braunholz, D, Erdmann, J, Moumni, M

“…Common Moroccan breeds D'man, Sardi, and Timahdite have been found to differ regarding litter size. D'man is known for its high prolificacy (2-7 lambs),…”
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