Search Results - "Aharchi, Fatima"
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Rapid HCV-RNA Decline With Once Daily TMC435: A Phase I Study in Healthy Volunteers and Hepatitis C Patients
Published in Gastroenterology (New York, N.Y. 1943) (01-03-2010)“…Background & Aims The search for targeted anti-hepatitis C virus (HCV) drugs is driven by the adverse effect profile and limited efficacy of the current…”
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Pharmacokinetic evaluation of the interaction between etravirine and rifabutin or clarithromycin in HIV-negative, healthy volunteers: results from two Phase 1 studies
Published in Journal of antimicrobial chemotherapy (01-03-2014)“…Drug-drug interactions between etravirine and rifabutin or clarithromycin were examined in two separate open-label, randomized, two-period, crossover trials in…”
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The effect of single- and multiple-dose etravirine on a drug cocktail of representative cytochrome P450 probes and digoxin in healthy subjects
Published in Journal of clinical pharmacology (01-04-2014)“…The effect of etravirine on cytochrome P450 (CYP) enzymes and P‐glycoprotein were evaluated in two randomized, crossover trials in healthy subjects. A modified…”
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Pharmacokinetics and Short-Term Safety of Etravirine in Combination With Fluconazole or Voriconazole in HIV-Negative Volunteers
Published in Journal of clinical pharmacology (01-01-2013)“…The nonnucleoside reverse transcriptase inhibitor etravirine, approved for use in treatment‐experienced, HIV‐1‐infected patients, is a substrate and inducer of…”
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Effect of steady-state etravirine on the pharmacokinetics and pharmacodynamics of ethinylestradiol and norethindrone
Published in Contraception (Stoneham) (01-07-2009)“…Abstract Background Etravirine, a non-nucleoside reverse transcriptase inhibitor (NNRTI) active against NNRTI-resistant HIV, is an inducer of CYP3A4 and an…”
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