Search Results - "Ahamad, Shahzaib"

PlantPepDB: A manually curated plant peptide database by Das, Durdam, Jaiswal, Mohini, Khan, Fatima Nazish, Ahamad, Shahzaib, Kumar, Shailesh

“…Plants produce an array of peptides as part of their innate defense mechanism against pathogens. The potential use of these peptides for various therapeutic…”
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Computational Design of Novel Tau-Tubulin Kinase 1 Inhibitors for Neurodegenerative Diseases by Ahamad, Shahzaib, Junaid, Iqbal Taliy, Gupta, Dinesh

“…The tau-tubulin kinase 1 (TTBK1) protein is a casein kinase 1 superfamily member located at chromosome 6p21.1. It is expressed explicitly in the brain,…”
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Anti-Fungal Drug Anidulafungin Inhibits SARS-CoV-2 Spike-Induced Syncytia Formation by Targeting ACE2-Spike Protein Interaction by Ahamad, Shahzaib, Ali, Hashim, Secco, Ilaria, Giacca, Mauro, Gupta, Dinesh

“…Drug repositioning continues to be the most effective, practicable possibility to treat COVID-19 patients. The severe acute respiratory syndrome coronavirus 2…”
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Implications of molecular diversity of chitin and its derivatives by Khan, Faez Iqbal, Rahman, Safikur, Queen, Aarfa, Ahamad, Shahzaib, Ali, Sher, Kim, Jihoe, Hassan, Md. Imtaiyaz

“…Chitin is a long unbranched polysaccharide, made up of β-1,4-linked N -acetylglucosamine which forms crystalline fiber-like structure. It is present in the…”
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Targeting cathepsins: A potential link between COVID-19 and associated neurological manifestations by Prasad, Kartikay, Ahamad, Shahzaib, Gupta, Dinesh, Kumar, Vijay

“…Many studies have shown that the lysosomal cathepsins, especially cathepsins B/L (CTSB/L) are required for SARS-CoV-2 entry into host cells. Lysosomal…”
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Insights into the structure and dynamics of SARS-CoV-2 spike glycoprotein double mutant L452R-E484Q by Ahamad, Shahzaib, Hema, Kanipakam, Ahmad, Shahnawaz, Kumar, Vijay, Gupta, Dinesh

“…The Receptor Binding Domain (RBD) of SARS-CoV-2, located on the S1 subunit, plays a vital role in the virus binding and its entry into the host cell through…”
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Identification of PARP12 Inhibitors By Virtual Screening and Molecular Dynamics Simulations by Almeleebia, Tahani M., Ahamad, Shahzaib, Ahmad, Irfan, Alshehri, Ahmad, Alkhathami, Ali G., Alshahrani, Mohammad Y., Asiri, Mohammed A., Saeed, Amir, Siddiqui, Jamshaid Ahmad, Yadav, Dharmendra K., Saeed, Mohd

“…Poly [adenosine diphosphate (ADP)-ribose] polymerases (PARPs) are members of a family of 17 enzymes that performs several fundamental cellular processes…”
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Atomic Resolution Homology Models and Molecular Dynamics Simulations of Plasmodium falciparum Tubulins by Hema, Kanipakam, Ahamad, Shahzaib, Joon, Hemant Kumar, Pandey, Rajan, Gupta, Dinesh

“…Microtubules are tubulin polymers present in the eukaryotic cytoskeleton essential for structural stability and cell division that are also roadways for…”
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Interactions Under Crowding Milieu: Chemical-Induced Denaturation of Myoglobin is Determined by the Extent of Heme Dissociation on Interaction with Crowders by Nasreen, Khalida, Parray, Zahoor Ahmad, Ahamad, Shahzaib, Ahmad, Faizan, Ahmed, Anwar, Freeh Alamery, Salman, Hussain, Tajamul, Hassan, Md Imtaiyaz, Islam, Asimul

“…Generally, in vivo function and structural changes are studied by probing proteins in a dilute solution under in vitro conditions, which is believed to be…”
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QSAR based therapeutic management of M. tuberculosis by Ahamad, Shahzaib, Rahman, Safikur, Khan, Faez Iqbal, Dwivedi, Neeraja, Ali, Sher, Kim, Jihoe, Imtaiyaz Hassan, Md

“…Mycobacterium tuberculosis is responsible for severe mortality and morbidity worldwide but, under-developed and developing countries are more prone to…”
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Synthesis, Characterization, Antiglycation Evaluation, Molecular Docking, and ADMET Studies of 4‑Thiazolidinone Derivatives by Haque, Ashanul, Khan, Mohd Wajid Ali, Alenezi, Khalaf M., Soury, Raoudha, Khan, Muhammad S., Ahamad, Shahzaib, Mushtaque, Md, Gupta, Dinesh

“…The design and development of new small-molecule glycation inhibitors are essential for preventing various chronic diseases, including diabetes mellitus,…”
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Targeting SARS-CoV-2 nucleocapsid oligomerization: Insights from molecular docking and molecular dynamics simulations by Ahamad, Shahzaib, Gupta, Dinesh, Kumar, Vijay

“…The outbreak of COVID-19 caused by SARS-CoV-2 virus continually led to infect a large population worldwide. Currently, there is no specific viral…”
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Insights into the structural and dynamical changes of spike glycoprotein mutations associated with SARS-CoV-2 host receptor binding by Ahamad, Shahzaib, Kanipakam, Hema, Gupta, Dinesh

“…Novel Coronavirus or SARS-CoV-2 has received worldwide attention due to the COVID-19 pandemic, which originated in Wuhan, China leading to thousands of deaths…”
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Structural stability predictions and molecular dynamics simulations of RBD and HR1 mutations associated with SARS-CoV-2 spike glycoprotein by Ahamad, Shahzaib, Hema, Kanipakam, Gupta, Dinesh

“…The COVID-19 pandemic is caused by human transmission and infection of Severe Acute Respiratory Syndrome Corona Virus-2 (SARS-CoV-2). There is no trusted drug…”
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The structural, functional, and dynamic effect of Tau tubulin kinase1 upon a mutation: A neuro‐degenerative hotspot by Ahamad, Shahzaib, Hema, Kanipakam, Kumar, Vijay, Gupta, Dinesh

“…Alzheimer's disease (AD) is a progressive disorder that causes brain cells to degenerate and die. AD is one of the common causes of dementia that leads to a…”
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A molecular journey to check the conformational dynamics of tau tubulin kinase 2 mutations associated with Alzheimer's disease by Ahamad, Shahzaib, Kanipakam, Hema, Kumar, Vijay, Gupta, Dinesh

“…Proteins are one of the most vital components of biological functions. Proteins have evolutionarily conserved structures as the shape and folding pattern…”
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Identification of Novel Tau-Tubulin Kinase 2 Inhibitors Using Computational Approaches by Ahamad, Shahzaib, Hema, Kanipakam, Gupta, Dinesh

“…Tau tubulin kinase 2 (TTBK2) associated with multiple diseases is one of the kinases which phosphorylates tau and tubulin. Numerous efforts have been made to…”
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Lead optimization, pharmacophore development and scaffold design of protein kinase CK2 inhibitors as potential COVID-19 therapeutics by Yadav, Siddharth, Ahamad, Shahzaib, Gupta, Dinesh, Mathur, Puniti

“…Therapeutic agents being designed against COVID-19 have targeted either the virus directly or the host cellular machinery. A particularly attractive host…”
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Screening Malaria-box compounds to identify potential inhibitors against SARS-CoV-2 M pro , using molecular docking and dynamics simulation studies by Ahamad, Shahzaib, Kanipakam, Hema, Birla, Shweta, Ali, Md Shaukat, Gupta, Dinesh

“…Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS-CoV-2) Main protease (M ) is one of the vital drug targets amongst all the coronaviruses, as the protein…”
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From ZikV genome to vaccine: in silico approach for the epitope‐based peptide vaccine against Zika virus envelope glycoprotein by Alam, Aftab, Ali, Shahnawaz, Ahamad, Shahzaib, Malik, Md. Zubbair, Ishrat, Romana

“…Summary Zika virus (ZikV) has emerged as a potential threat to human health worldwide. A member of the Flaviviridae, ZikV is transmitted to humans by…”
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