Search Results - "Agwa, Sara H A"
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Prospective insight into the role of benzyl propylene glycoside as a modulator of the cGAS-STING signaling pathway in the management of nonalcoholic fatty pancreas animal model
Published in Biological research (13-03-2023)“…Nonalcoholic fatty pancreatitis (NAFP) is one of the metabolic syndrome manifestations that need further studies to determine its molecular determinants and…”
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Identification of a Multi-Messenger RNA Signature as Type 2 Diabetes Mellitus Candidate Genes Involved in Crosstalk between Inflammation and Insulin Resistance
Published in Biomolecules (Basel, Switzerland) (01-09-2022)“…Type 2 Diabetes Mellitus (T2DM) is a metabolic disease associated with inflammation widening the scope of immune-metabolism, linking the inflammation to…”
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Rosavin Ameliorates Hepatic Inflammation and Fibrosis in the NASH Rat Model via Targeting Hepatic Cell Death
Published in International journal of molecular sciences (01-09-2022)“…Background: Non-alcoholic fatty liver disease (NAFLD) represents the most common form of chronic liver disease that urgently needs effective therapy. Rosavin,…”
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Predictive urinary RNA biomarkers of kidney injury after extracorporeal shock wave lithotripsy
Published in World journal of urology (01-06-2022)“…Background Extracorporeal shock wave lithotripsy (ESWL) is considered one of the best choices for the treatment of various kinds of urinary tract calculi,…”
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Analysis of mRNA-miRNA-lncRNA differential expression in prediabetes/type 2 diabetes mellitus patients as potential players in insulin resistance
Published in Frontiers in endocrinology (Lausanne) (08-05-2023)“…Type 2 diabetes mellitus (T2DM) is a major global health concern. It usually develops gradually and is frequently preceded by undetectable pre-diabetes…”
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Clinical Significance of HSPD1/MMP14/ITGB1/miR-6881-5P/Lnc-SPARCL1-1:2 RNA Panel in NAFLD/NASH Diagnosis: Egyptian Pilot Study
Published in Biomedicines (17-09-2021)“…Background: Non-alcoholic steatohepatitis ((NASH) is the progressive form of (non-alcoholic fatty liver disease) (NAFLD), which can progress to liver cirrhosis…”
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ABHD4-Regulating RNA Panel: Novel Biomarkers in Acute Coronary Syndrome Diagnosis
Published in Cells (Basel, Switzerland) (16-06-2021)“…Background: Acute coronary syndrome (ACS) is a major cause of death all over the world. STEMI represents a type of myocardial infarction with acute ST…”
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Impact of circ-0000221 in the Pathogenesis of Hepatocellular via Modulation of miR-661-PTPN11 mRNA Axis
Published in Pharmaceutics (06-01-2022)“…Hepatocellular carcinoma (HCC) is a leading cause of cancer-related death in Egypt. A deep understanding of the molecular events occurring in HCC can…”
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In Silico Identification and Clinical Validation of a Novel Long Non-Coding RNA/mRNA/miRNA Molecular Network for Potential Biomarkers for Discriminating SARS CoV-2 Infection Severity
Published in Cells (Basel, Switzerland) (09-11-2021)“…(1) Background: The coronavirus (COVID-19) pandemic is still a major global health problem, despite the development of several vaccines and diagnostic assays…”
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Identifying SARS-CoV-2 Lineage Mutation Hallmarks and Correlating Them With Clinical Outcomes in Egypt: A Pilot Study
Published in Frontiers in molecular biosciences (08-03-2022)“…The SARS-CoV-2 pandemic has led to over 4.9 million deaths as of October 2021. One of the main challenges of creating vaccines, treatment, or diagnostic tools…”
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Identification of Novel Molecular Network Expression in Acute Myocardial Infarction
Published in Current genomics (01-08-2019)“…Background: In the current study, we aimed to analyze the hypothesis that human myocardial- specific extracellular RNAs expression could be used for acute…”
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Discriminatory power of a circulating multi-noncoding RNA panel in acute coronary syndrome subtypes: Towards precision detection
Published in The international journal of biochemistry & cell biology (01-04-2024)“…Acute Coronary Syndrome (ACS) stands as a significant contributor to cardiovascular mortality, necessitating improved diagnostic tools for early detection and…”
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Anti-inflammatory effect of trans-anethol in a rat model of myocardial ischemia-reperfusion injury
Published in Biomedicine & pharmacotherapy (01-06-2022)“…Myocardial ischemia‑reperfusion injury (MI/R) is considered a main risk factor for global cardiac mortality and morbidity, for which no effective treatment…”
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Association between Interferon-Lambda-3 rs12979860, TLL1 rs17047200 and DDR1 rs4618569 Variant Polymorphisms with the Course and Outcome of SARS-CoV-2 Patients
Published in Genes (28-05-2021)“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection provides a critical host-immunological challenge. We explore the effect of host-genetic…”
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Circulatory Endothelin 1- Regulating RNAs Panel: Promising Biomarkers for Non-Invasive NAFLD/NASH Diagnosis and Stratification: Clinical and Molecular Pilot Study
Published in Genes (18-11-2021)“…Nonalcoholic fatty liver disease (NAFLD) is one of the major seeds of liver cirrhosis and hepatocellular carcinoma. There is no convenient reliable…”
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Detection of circulating tumor cells by nested RT-PCR targeting EGFR/CEA/CK20mRNAs in colorectal carcinoma patients
Published in The Egyptian journal of medical human genetics (01-11-2010)“…EGFR is involved in the epidermal growth factors pathway that regulates cellular processes and is associated with the development of many types of cancer…”
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Multiple molecular markers MAGE-1, MAGE-3 and AFP mRNAs expression nested PCR assay for sensitive and specific detection of circulating hepatoma cells: Enhanced detection of hepatocellular carcinoma
Published in The Egyptian journal of medical human genetics (01-01-2013)“…Hepatocellular Carcinoma is a multifactorial, multistep and complex process. Its prognosis is poor and early diagnosis and monitoring of metastasis of HCC is…”
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Serine protease (TPS): A diagnostic and prognostic marker in pediatric patients with acute non-lymphoblastic leukemia
Published in The Egyptian journal of medical human genetics (01-11-2011)“…The Serine protease, TPS (tryptase), is a specific marker for mast cells and mast cell-associated disorders. However, substantial amounts of TPS are also…”
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Pilot study for assessment of prevalence of intrafamilial hepatitis C transmission in relation to salivary viral load among infected patients with and without chronic renal failure
Published in The Egyptian journal of medical human genetics (01-02-2012)“…HCV-RNA in saliva of HCV patients provides a biological basis for its potential transmission. HCV viremia is particularly high in HCV patients on hemodialysis…”
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Molecular detection of circulating thyroid specific transcripts (TSHR/Tg-mRNAs) in thyroid cancer patients: Their diagnostic significance
Published in The Egyptian journal of medical human genetics (01-11-2011)“…Thyroid cancer is the most prevalent endocrine malignancy. The preoperative diagnosis of differentiated thyroid cancer (DTC) that relies solely on fine-needle…”
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