Search Results - "Agutter, P S"
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The aetiology of deep venous thrombosis
Published in QJM : An International Journal of Medicine (01-09-2006)“…Most ideas about the pathogenesis of deep venous thrombosis (DVT) are dominated by a 'consensus model' first articulated around 1962. This model invokes…”
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To what extent might deep venous thrombosis and chronic venous insufficiency share a common etiology?
Published in International angiology (01-08-2009)“…According to the valve cusp hypoxia hypothesis (VCHH), deep venous thrombosis is caused by sustained non-pulsatile (streamline) venous blood flow. This leads…”
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3
Nucleocytoplasmic transport
Published in Biochemical journal (15-06-1994)“…The nucleus and cytoplasm in eukaryotes are physically separated throughout interphase. The two compartments differ markedly in composition and function, but…”
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Intracellular transport mechanisms: a critique of diffusion theory
Published in Journal of theoretical biology (21-09-1995)“…It is argued that Brownian motion makes a less significant contribution to the movements of molecules and particles inside cells than is commonly believed, and…”
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Role of the cytoskeleton in nucleocytoplasmic RNA and protein distributions
Published in Biochemical Society transactions (01-11-1991)“…Establishment and maintenance of correct partitioning of proteins and RNA molecules between nucleus and cytoplasm in a sine qua non of the viability of…”
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Diffusion Theory in Biology: A Relic of Mechanistic Materialism
Published in Journal of the history of biology (01-01-2000)“…Diffusion theory explains in physical terms how materials move through a medium, e.g. water or a biological fluid. There are strong and widely acknowledged…”
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Poly(A) binding proteins located at the inner surface of resealed nuclear envelopes
Published in The Journal of biological chemistry (25-04-1990)“…We have used a photoreactive cross-linking reagent, poly(A/8-N3-A) (a poly(A) of average molecular mass of 100 kDa in which 5-10% of the A residues are…”
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Immunological evidence for the localization of a 110 kDa poly(A) binding protein from rat liver in nuclear envelopes and its phosphorylation by protein kinase C
Published in Cellular and molecular biology (Noisy-le-Grand, France) (01-11-1993)“…We have purified a 110 kDa poly(A) binding protein (P110) from rat liver which is thought to be involved in mRNA translocation through the nuclear pores and…”
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Random walks and cell size
Published in BioEssays (01-11-2000)“…For many years, it has been believed that diffusion is the principle motive force for distributing molecules within the cell. Yet, our current information…”
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Nuclear non-chromatin proteinaceous structures: their role in the organization and function of the interphase nucleus
Published in Journal of cell science (01-08-1980)Get full text
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Influence of nucleotides, cations and nucleoside triphosphatase inhibitors on the release of ribonucleic acid from isolated rat liver nuclei
Published in Biochemical journal (15-04-1980)“…The reasons underlying reported discrepancies in the effects of ATP, ADP, adenosine 5'-[beta gamma-methylene]triphosphate, AMP + PPi, P-chloromercuribenzoate…”
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Evidence for involvement of nuclear envelope nucleoside triphosphatase in nucleocytoplasmic translocation of ribonucleoprotein
Published in Nature (London) (09-09-1976)Get full text
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An assessment of some methodological criticisms of studies of RNA efflux from isolated nuclei
Published in Biochemical journal (15-09-1983)“…RNA efflux from isolated nuclei can be studied either as a means of elucidating the general mechanism of nucleo-cytoplasmic RNA transport, or as part of an…”
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Inhibition of ribonucleic acid efflux from isolated SV40-3T3 cell nuclei by 3'-deoxyadenosine (cordycepin)
Published in Biochemical journal (15-05-1979)“…The effect of 3'-deoxyadenosine (cordycepin) on mRNA efflux from isolated SV40-3T3 cell nuclei has been studied and compared with its effect on the nucleoside…”
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Variability of mammalian liver nuclear-envelope preparations
Published in Biochemical journal (15-10-1980)“…The composition, density and enzymic activities of sheep liver nuclear-envelope preparations were found to vary markedly according to the concentrations of…”
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Ribonucleic acid stimulation of mammalian liver nuclear-envelope nucleoside triphosphatase. A possible enzymic marker for the nuclear envelope
Published in Biochemical journal (15-03-1977)“…1. The specific activity of rat and pig liver nuclear-envelope nucleoside triphosphatase (EC 3.6.1.3) decreases when the system is depleted of RNA. The…”
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Models of the interactions between membranes and intracellular protein structures
Published in Biochemical Society transactions (01-08-1984)Get more information
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The isolation of the envelopes of rat liver nuclei
Published in Biochimica et biophysica acta (17-01-1972)Get more information
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Properties of mammalian nuclear-envelope nucleoside triphosphatase
Published in Biochemical journal (01-09-1979)“…The nucleoside triphosphatase activities of the nuclear envelopes from rat liver, pig liver and simian-virus-40-transformed mouse-embryo 3T3 cells were shown…”
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The isolation of nuclear envelopes. Effects of thiol-group oxidation and of calcium ions
Published in Biochemical journal (15-02-1985)“…The effects of (a) oxidative cross-linking of protein thiol groups and (b) the presence or absence of Ca2+ ions on rat liver nuclear-envelope isolation were…”
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