Search Results - "Aguirre, Pabla"

Development of an iron-selective antioxidant probe with protective effects on neuronal function by García-Beltrán, Olimpo, Mena, Natalia P, Aguirre, Pabla, Barriga-González, Germán, Galdámez, Antonio, Nagles, Edgar, Adasme, Tatiana, Hidalgo, Cecilia, Núñez, Marco T

“…Iron accumulation, oxidative stress and calcium signaling dysregulation are common pathognomonic signs of several neurodegenerative diseases, including…”
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Parkinson's Disease: The Mitochondria-Iron Link by Muñoz, Yorka, Carrasco, Carlos M., Campos, Joaquín D., Aguirre, Pabla, Núñez, Marco T.

“…Mitochondrial dysfunction, iron accumulation, and oxidative damage are conditions often found in damaged brain areas of Parkinson’s disease. We propose that a…”
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Iron Chelators and Antioxidants Regenerate Neuritic Tree and Nigrostriatal Fibers of MPP+/MPTP-Lesioned Dopaminergic Neurons by Aguirre, Pabla, Mena, Natalia P, Carrasco, Carlos M, Muñoz, Yorka, Pérez-Henríquez, Patricio, Morales, Rodrigo A, Cassels, Bruce K, Méndez-Gálvez, Carolina, García-Beltrán, Olimpo, González-Billault, Christian, Núñez, Marco T

“…Neuronal death in Parkinson's disease (PD) is often preceded by axodendritic tree retraction and loss of neuronal functionality. The presence of non-functional…”
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Synthesis and characterization of a novel fluorescent and colorimetric probe for the detection of mercury (II) even in the presence of relevant biothiols by García-Beltrán, Olimpo, Rodríguez, Alejandra, Trujillo, Ariel, Cañete, Alvaro, Aguirre, Pabla, Gallego-Quintero, Sebastián, Nuñez, Marco T., Aliaga, Margarita E.

“…[Display omitted] We present here a novel probe, coumarin 3-azomethine derivative (AGB), which can detect selectively mercuric ions (Hg2+) via a hydrolysis…”
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Iron supply determines apical/basolateral membrane distribution of intestinal iron transporters DMT1 and ferroportin 1 by Núñez, Marco T, Tapia, Victoria, Rojas, Alejandro, Aguirre, Pabla, Gómez, Francisco, Nualart, Francisco

“…Intestinal iron absorption comprises the coordinated activity of the influx transporter divalent metal transporter 1 (DMT1) and the efflux transporter…”
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Iron homeostasis in neuronal cells: a role for IREG1 by Aguirre, Pabla, Mena, Natalia, Tapia, Victoria, Arredondo, Miguel, Núñez, Marco T

“…Iron is necessary for neuronal function but in excess generates neurodegeneration. Although most of the components of the iron homeostasis machinery have been…”
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Effect of iron on the activation of the MAPK/ERK pathway in PC12 neuroblastoma cells by Muñoz, Pablo, Zavala, Gabriela, Castillo, Karen, Aguirre, Pabla, Hidalgo, Cecilia, Núñez, Marco T

“…Recent evidence suggests that reactive oxygen species function as second messenger molecules in normal physiological processes. For example, activation of…”
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Iron and glutathione at the crossroad of redox metabolism in neurons by Aracena, Paula, Aguirre, Pabla, Muñoz, Pablo, Núñez, Marco T

“…Neurons, as non-dividing cells, encounter a myriad of stressful conditions throughout their lifespan. In particular, there is increasing evidence that iron…”
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Inflammation alters the expression of DMT1, FPN1 and hepcidin, and it causes iron accumulation in central nervous system cells by Urrutia, Pamela, Aguirre, Pabla, Esparza, Andrés, Tapia, Victoria, Mena, Natalia P., Arredondo, Miguel, González‐Billault, Christian, Núñez, Marco T.

“…Inflammation and iron accumulation are present in a variety of neurodegenerative diseases that include Alzheimer's disease and Parkinson's disease. The study…”
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Calcium is a noncompetitive inhibitor of DMT1 on the intestinal iron absorption process: empirical evidence and mathematical modeling analysis by Cegarra, Layimar, Aguirre, Pabla, Nuñez, Marco T, Gerdtzen, Ziomara P, Salgado, J Cristian

“…Iron absorption is a complex and highly controlled process where DMT1 transports nonheme iron through the brush-border membrane of enterocytes to the cytoplasm…”
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Antioxidant responses of cortex neurons to iron loading by Aguirre, Pabla, Mena, Natalia, Tapia, Victoria, Rojas, Alejandro, Arredondo, Miguel, Núñez, Marco Tulio

“…Brain cells have a highly active oxidative metabolism, yet they contain only low to moderate superoxide dismutase and catalase activities. Thus, their…”
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Iron toxicity in neurodegeneration by Núñez, Marco T., Urrutia, Pamela, Mena, Natalia, Aguirre, Pabla, Tapia, Victoria, Salazar, Julio

“…Iron is an essential element for life on earth, participating in a plethora of cellular processes where one-electron transfer reactions are required. Its…”
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Cell death induced by mitochondrial complex I inhibition is mediated by Iron Regulatory Protein 1 by Urrutia, Pamela J., Aguirre, Pabla, Tapia, Victoria, Carrasco, Carlos M., Mena, Natalia P., Núñez, Marco T.

“…Mitochondrial dysfunction and oxidative damage, often accompanied by elevated intracellular iron levels, are pathophysiological features in a number of…”
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The dopamine metabolite aminochrome inhibits mitochondrial complex I and modifies the expression of iron transporters DMT1 and FPN1 by Aguirre, Pabla, Urrutia, Pamela, Tapia, Victoria, Villa, Monica, Paris, Irmgad, Segura-Aguilar, Juan, Núñez, Marco T.

“…Hallmarks of idiopathic and some forms of familial Parkinson’s disease are mitochondrial dysfunction, iron accumulation and oxidative stress in dopaminergic…”
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Neuroprotective Effect of a New 7,8-Dihydroxycoumarin-Based Fe2+/Cu2+ Chelator in Cell and Animal Models of Parkinson’s Disease by Aguirre, Pabla, García-Beltrán, Olimpo, Tapia, Victoria, Muñoz, Yorka, Cassels, Bruce K, Núñez, Marco T

“…Disturbed iron homeostasis, often coupled to mitochondrial dysfunction, plays an important role in the progression of common neurodegenerative diseases such as…”
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Detection of SO 2 derivatives using a new chalco-coumarin derivative in cationic micellar media: application to real samples by Gómez, Marisol, Aliaga, Margarita E, Arancibia, Verónica, Moya, Alexis, Segura, Camilo, Nuñez, Marco T, Aguirre, Pabla, Nagles, Edgar, García-Beltrán, Olimpo

“…A new probe ( )-7-(diethylamino)-3-(3-(thiophen-2-yl)acryloyl)-2 -chromen-2-one (ChC16) was synthesized and studied as a turn-on fluorescent probe, based on a…”
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Detection of SO2 derivatives using a new chalco-coumarin derivative in cationic micellar media: application to real samples by Gómez, Marisol, Aliaga, Margarita E, Arancibia, Verónica, Moya, Alexis, Segura, Camilo, Nuñez, Marco T, Aguirre, Pabla, Nagles, Edgar, García-Beltrán, Olimpo

“…A new probe (E)-7-(diethylamino)-3-(3-(thiophen-2-yl)acryloyl)-2H-chromen-2-one (ChC16) was synthesized and studied as a turn-on fluorescent probe, based on a…”
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Inflammation alters the expression of DMT 1, FPN 1 and hepcidin, and it causes iron accumulation in central nervous system cells by Urrutia, Pamela, Aguirre, Pabla, Esparza, Andrés, Tapia, Victoria, Mena, Natalia P., Arredondo, Miguel, González‐Billault, Christian, Núñez, Marco T.

“…Inflammation and iron accumulation are present in a variety of neurodegenerative diseases that include Alzheimer's disease and Parkinson's disease. The study…”
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Neuroprotective Effect of a New 7,8-Dihydroxycoumarin-Based Fe 2+ /Cu 2+ Chelator in Cell and Animal Models of Parkinson's Disease by Aguirre, Pabla, García-Beltrán, Olimpo, Tapia, Victoria, Muñoz, Yorka, Cassels, Bruce K, Núñez, Marco T

“…Disturbed iron homeostasis, often coupled to mitochondrial dysfunction, plays an important role in the progression of common neurodegenerative diseases such as…”
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Detection of SO2 derivatives using a new chalco-coumarin derivative in cationic micellar media: application to real samplesElectronic supplementary information (ESI) available. See DOI: 10.1039/c8ra04526g by Gómez, Marisol, Aliaga, Margarita E, Arancibia, Verónica, Moya, Alexis, Segura, Camilo, Nuñez, Marco T, Aguirre, Pabla, Nagles, Edgar, García-Beltrán, Olimpo

“…A new probe ( E )-7-(diethylamino)-3-(3-(thiophen-2-yl)acryloyl)-2 H -chromen-2-one ( ChC16 ) was synthesized and studied as a turn-on fluorescent probe, based…”
Get full text