Bullous pemphigoid in a 3-month-old infant: case report and literature review of this dermatosis in childhood

Bullous pemphigoid in a 3-month-old infant: case report and literature review of this dermatosis in childhood

Bullous pemphigoid is an autoimmune subepidermal blistering dermatosis that is uncommon in childhood. We report a case of a female infant, 3 months old, which presented clinical and laboratory data for the confirmatory diagnosis of bullous pemphigoid. The authors used immunohistochemical staining fo...

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Bibliographic Details
Published in:Anais brasileiros de dermatología Vol. 88; no. 6; pp. 961 - 965
Main Authors: Reis-Filho, Eugenio Galdino de Mendonça, Silva, Tainah de Almeida, Aguirre, Luiza Helena de Lima, Reis, Carmelia Matos Santiago
Format: Journal Article
Language:English
Published: Brazil Sociedade Brasileira de Dermatologia 01-12-2013
Subjects:
Blister - drug therapy
Blister - pathology
Child
Collagen Type I - analysis
Collagen type IV
DERMATOLOGY
Diagnosis, Differential
Female
Humans
Immunohistochemistry
Infant
Pemphigoid, bullous
Pemphigoid, Bullous - drug therapy
Pemphigoid, Bullous - pathology
Review
Skin - pathology
Skin diseases, vesiculobullous
Treatment Outcome
Dermatopatias vesiculobolhosas
Penfigóide bolhoso
Pemphigoid, bullous
Collagen type IV
Colágeno Tipo IV
Child
Criança
Skin diseases, vesiculobullous
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Summary:Bullous pemphigoid is an autoimmune subepidermal blistering dermatosis that is uncommon in childhood. We report a case of a female infant, 3 months old, which presented clinical and laboratory data for the confirmatory diagnosis of bullous pemphigoid. The authors used immunohistochemical staining for collagen type IV that allowed the differentiation of bullous pemphigoid from other subepidermal bullous diseases. Opportunely we review the clinical, immunological, therapeutic and prognostic features of this pathology in children.
Bibliography:ObjectType-Case Study-3
SourceType-Scholarly Journals-1
content type line 23
ObjectType-Review-1
ObjectType-Feature-5
ObjectType-Report-2
ObjectType-Article-4
ISSN:0365-0596
1806-4841
1806-4841
0365-0596
DOI:10.1590/abd1806-4841.20132378