Search Results - "Aguilera Rodríguez, Raul"

Body Mass Index Is Significantly Associated With Disease Severity in Spinocerebellar Ataxia Type 2 Patients by Almaguer‐Mederos, Luis E., Pérez‐Ávila, Ilbedis, Aguilera‐Rodríguez, Raúl, Velázquez‐Garcés, Maria, Almaguer‐Gotay, Dennis, Hechavarría‐Pupo, Ricardo, Rodríguez‐Estupiñán, Annelié, Auburger, Georg

“…ABSTRACT Background Spinocerebellar ataxia type 2 is a progressive neurodegenerative disorder due to an unstable expansion of a CAG repeat in the ATXN2 gene…”
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Progression of early features of spinocerebellar ataxia type 2 in individuals at risk: a longitudinal study by Velázquez-Pérez, Luis, Dr Prof, Rodríguez-Labrada, Roberto, PhD, Canales-Ochoa, Nalia, BSc, Montero, Jacqueline Medrano, PhD, Sánchez-Cruz, Gilberto, PhD, Aguilera-Rodríguez, Raúl, MD, Almaguer-Mederos, Luis E, PhD, Laffita-Mesa, José M, BSc

“…Summary Background The effects of ATXN2 expansion on the nervous system arise before the cerebellar syndrome can be diagnosed; however, progression of the…”
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Neurorehabilitation therapy in spinocerebellar ataxia type 2: A 24‐week, rater‐blinded, randomized, controlled trial by Rodríguez‐Díaz, Julio Cesar, Velázquez‐Pérez, Luis, Rodríguez Labrada, Roberto, Aguilera Rodríguez, Raúl, Laffita Pérez, Dalina, Canales Ochoa, Nalia, Medrano Montero, Jacqueline, Estupiñán Rodríguez, Annelié, Osorio Borjas, Marcos, Góngora Marrero, Mariela, Reynaldo Cejas, Lorenzo, González Zaldivar, Yanetza, Almaguer Gotay, Dennis

“…ABSTRACT Background: Neurorehabilitation has become in a widely used approach in spinocerebellar ataxias, but there are scarce powerful clinical studies…”
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Redox Imbalance Associates with Clinical Worsening in Spinocerebellar Ataxia Type 2 by Dennis, Almaguer-Gotay, Almaguer-Mederos, Luis E., Raúl, Rodríguez-Aguilera, Roberto, Rodríguez-Labrada, Luis, Velázquez-Pérez, Dany, Cuello-Almarales, Yanetza, González-Zaldívar, Yaimeé, Vázquez-Mojena, Annelié, Estupiñán-Domínguez, Arnoy, Peña-Acosta, Reydenis, Torres-Vega

“…Background. Spinocerebellar ataxia type 2 (SCA2) is a neurodegenerative disease presenting with redox imbalance. However, the nature and implications of redox…”
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Normal ATXN2 alleles influences on the age at onset in spinocerebellar ataxia type 2 by Almaguer‐Mederos, Luis E., Aguilera‐Rodríguez, Raúl, Cuello‐Almarales, Dany, Almaguer‐Gotay, Dennis, González‐Zaldívar, Yanetza, Vázquez‐Mojena, Yaimé, Santos‐Falcón, Nieves, Sánchez‐Cruz, Gilberto, Velázquez‐Pérez, Luis

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Testosterone Levels Are Decreased and Associated with Disease Duration in Male Spinocerebellar Ataxia Type 2 Patients by Almaguer-Mederos, Luis E., Aguilera-Rodríguez, Raúl, Almaguer-Gotay, Dennis, Hechavarría-Barzaga, Kenia, Álvarez-Sosa, Amarilis, Chapman-Rodríguez, Yamilé, Silva-Ricardo, Yanelis, González-Zaldivar, Yanetza, Vázquez-Mojena, Yaimé, Cuello-Almarales, Dany, Rodríguez-Estupiñán, Annelié

“…Spinocerebellar ataxia type 2 (SCA2) is a progressive neurodegenerative disorder due to an unstable expansion of a CAG repeat in the ATXN2 gene. Despite…”
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Brain atrophy measures in preclinical and manifest spinocerebellar ataxia type 2 by Reetz, Kathrin, Rodríguez‐Labrada, Roberto, Dogan, Imis, Mirzazade, Shahram, Romanzetti, Sandro, Schulz, Jörg B., Cruz‐Rivas, Edilia M., Alvarez‐Cuesta, Jose A., Aguilera Rodríguez, Raul, Gonzalez Zaldivar, Yanetza, Auburger, Georg, Velázquez‐Pérez, Luis

“…Objective Spinocerebellar ataxia type 2 (SCA2) is an autosomal dominantly inherited neurodegenerative disease mainly affecting the cerebellum and brainstem. In…”
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Executive deficit in spinocerebellar ataxia type 2 is related to expanded CAG repeats: Evidence from antisaccadic eye movements by Rodríguez-Labrada, Roberto, Velázquez-Pérez, Luis, Aguilera-Rodríguez, Raúl, Seifried-Oberschmidt, Carola, Peña-Acosta, Arnoy, Canales-Ochoa, Nalia, Medrano-Montero, Jacqueline, Estupiñan-Rodríguez, Annelié, Vázquez-Mojena, Yaimeé, González-Zaldivar, Yanetza, Laffita Mesa, Jose M.

“…Although antisaccadic task is a sensitive research tool in psychopathology, it has not been systematically studied in patients with spinocerebellar ataxia type…”
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Molecular epidemiology of spinocerebellar ataxias in Cuba: Insights into SCA2 founder effect in Holguin by Velázquez Pérez, Luis, Cruz, Gilberto Sánchez, Santos Falcón, Nieves, Enrique Almaguer Mederos, Luis, Escalona Batallan, Karel, Rodríguez Labrada, Roberto, Paneque Herrera, Milena, Laffita Mesa, José Miguel, Rodríguez Díaz, Julio C., Rodríguez, Raúl Aguilera, González Zaldivar, Yanetza, Coello Almarales, Dany, Almaguer Gotay, Dennis, Jorge Cedeño, Humberto

“…The objective of this study was to determine the prevalence of hereditary ataxias in Cuba, with a special focus on the clinical and molecular features of SCA2…”
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Progression markers of Spinocerebellar Ataxia 2. A twenty years neurophysiological follow up study by Velázquez-Perez, Luis, Rodríguez-Labrada, Roberto, Canales-Ochoa, Nalia, Sanchez-Cruz, Gilberto, Fernandez-Ruiz, Juan, Montero, Jacqueline Medrano, Aguilera-Rodríguez, Raúl, Diaz, Rosalinda, Almaguer-Mederos, Luis E, Truitz, Agustín Palomino

“…Abstract Nerve conduction is profoundly affected in Spinocerebellar ataxia 2 (SCA2) even before the onset of the disease, but there is no information regarding…”
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Saccadic latency is prolonged in Spinocerebellar Ataxia type 2 and correlates with the frontal-executive dysfunctions by Rodríguez-Labrada, Roberto, Velázquez-Pérez, Luis, Seigfried, Carola, Canales-Ochoa, Nalia, Auburger, Georg, Medrano-Montero, Jacqueline, Sánchez-Cruz, Gilberto, Aguilera-Rodríguez, Raúl, Laffita-Mesa, José, Vázquez-Mojena, Yaimeé, Verdecia-Ramirez, Marisleydis, Motta, Maribel, Quevedo-Batista, Yudith

“…Abstract Data on saccadic latency in patients with Spinocerebellar Ataxia 2 (SCA2) are sparse and contradictory. In order to determine whether saccadic latency…”
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Spinocerebellar Ataxia Type 2 Is Associated with the Extracellular Loss of Superoxide Dismutase but Not Catalase Activity by Almaguer-Gotay, Dennis, Almaguer-Mederos, Luis E, Aguilera-Rodríguez, Raul, Rodríguez-Labrada, Roberto, Cuello-Almarales, Dany, Estupiñán-Domínguez, Annelié, Velázquez-Pérez, Luis C, González-Zaldívar, Yanetza, Vázquez-Mojena, Yaimé

“…Spinocerebellar ataxia type 2 (SCA2) is an inherited and still incurable neurodegenerative disorder. Evidence suggests that pro-oxidant agents as well as…”
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Ethical Dilemmas in Genetic Testing: Examples from the Cuban Program for Predictive Diagnosis of Hereditary Ataxias by Mariño, Tania Cruz, Armiñán, Rubén Reynaldo, Cedeño, Humberto Jorge, Mesa, José Miguel Laffita, Zaldivar, Yanetza González, Rodríguez, Raúl Aguilera, Santos, Miguel Velázquez, Mederos, Luis Enrique Almaguer, Herrera, Milena Paneque, Pérez, Luis Velázquez

“…Predictive testing protocols are intended to help patients affected with hereditary conditions understand their condition and make informed reproductive…”
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One‑carbon metabolism factor MTHFR variant is associated with saccade latency in Spinocerebellar Ataxia type 2 by Almaguer-Mederos, Luis E., Jorge-Sainz, Yasnay, Almaguer-Gotay, Dennis, Aguilera-Rodríguez, Raúl, Rodríguez-Labrada, Roberto, Velázquez-Pérez, Luis, González-Zaldívar, Yanetza, Cuello-Almarales, Dany, Vázquez-Mojena, Yaimé, Canales-Ochoa, Nalia, Aguiar-Santiago, Jorge, Auburger, Georg, MacLeod, Patrick

“…Spinocerebellar ataxia type 2 (SCA2) is a neurodegenerative disorder due to a CAG-repeat expansion. This work is intended to identify modifiers of the clinical…”
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Association of glutathione S-transferase omega polymorphism and spinocerebellar ataxia type 2 by Almaguer-Mederos, Luis E., Almaguer-Gotay, Dennis, Aguilera-Rodríguez, Raúl, González-Zaldívar, Yanetza, Cuello-Almarales, Dany, Laffita-Mesa, José, Vázquez-Mojena, Yaimé, Zayas-Feria, Pedro, Rodríguez-Labrada, Roberto, Velázquez-Pérez, Luis, MacLeod, Patrick

“…Spinocerebellar ataxia type 2 is a neurodegenerative disorder caused by a CAG repeat expansion in ATXN2 gene. There is high clinical variability among affected…”
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Strategy use, planning, and rule acquisition deficits in spinocerebellar ataxia type 2 patients by Vaca-Palomares, Israel, Díaz, Rosalinda, Rodríguez-Labrada, Roberto, Medrano-Montero, Jacqueline, Aguilera-Rodríguez, Raúl, Vázquez-Mojena, Yaimeé, Fernandez-Ruiz, Juan, Velázquez-Pérez, Luis

“…Our goal was to improve spinocerebellar ataxia type 2 (SCA2) cognitive profile characterization by testing the hypothesis that strategy, planning and rule…”
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Buccal Cell Micronucleus Frequency Is Significantly Elevated in Patients with Spinocerebellar Ataxia Type 2 by Cuello-Almarales, Dany A., Almaguer-Mederos, Luis E., Vázquez-Mojena, Yaimé, Almaguer-Gotay, Dennis, Zayas-Feria, Pedro, Laffita-Mesa, José M., González-Zaldívar, Yanetza, Aguilera-Rodríguez, Raúl, Rodríguez-Estupiñán, Annelié, Velázquez-Pérez, Luis

“…Spinocerebellar ataxia type 2 (SCA2) is part of a group of at least nine dominantly inherited disorders characterized by progressive degeneration of specific…”
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Sleep disorders in spinocerebellar ataxia type 2 patients by Velázquez-Pérez, Luis, Voss, Ursula, Rodríguez-Labrada, Roberto, Auburger, Georg, Canales Ochoa, Nalia, Sánchez Cruz, Gilberto, Galicia Polo, Lourdes, Haro Valencia, Reyes, Aguilera Rodríguez, Raúl, Medrano Montero, Jacqueline, Laffita Mesa, Jose M, Tuin, Inka

“…Sleep disturbances are common features in spinocerebellar ataxias (SCAs). Nevertheless, sleep data on SCA2 come from scarce studies including few patients,…”
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Oral Zinc Sulphate Supplementation for Six Months in SCA2 Patients: A Randomized, Double-Blind, Placebo-Controlled Trial by Velázquez-Pérez, Luis, Rodríguez-Chanfrau, Jorge, García-Rodríguez, Julio Cesar, Sánchez-Cruz, Gilberto, Aguilera-Rodríguez, Raúl, Rodríguez-Labrada, Roberto, Rodríguez-Díaz, Julio Cesar, Canales-Ochoa, Nalia, Gotay, Dennis Almaguer, Almaguer Mederos, Luis E., Laffita Mesa, José M., Porto-Verdecia, Marlene, Triana, Consuelo González, Pupo, Noemí Rodríguez, Batista, Idania Hidalgo, López-Hernandez, Orestes D., Polanco, Iverlis Díaz, Novas, Arelis Jayme

“…Cuban patients with Spinocerebellar Ataxia type 2 (SCA2) have reduced concentrations of zinc in serum and cerebrospinal fluid (CSF). To assess the effect and…”
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SCA2 predictive testing in Cuba: challenging concepts and protocol evolution by Cruz-Mariño, Tania, Vázquez-Mojena, Yaimeé, Velázquez-Pérez, Luis, González-Zaldívar, Yanetza, Aguilera-Rodríguez, Raúl, Velázquez-Santos, Miguel, Estupiñán-Rodríguez, Annelié, Laffita-Mesa, José Miguel, Almaguer-Mederos, Luis E., Paneque, Milena

“…Spinocerebellar ataxia type 2 (SCA2) is a neurodegenerative disease caused by a CAG repeat expansion in the ATXN2 gene. Cuba has the highest prevalence (6.57…”
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