Search Results - "Aguilar, Melissa S."
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CD4 and CD8 co-receptors modulate functional avidity of CD1b-restricted T cells
Published in Nature communications (10-01-2022)“…T cells recognize mycobacterial glycolipid (mycolipid) antigens presented by CD1b molecules, but the role of CD4 and CD8 co-receptors in mycolipid recognition…”
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Vaccination with mycobacterial lipid loaded nanoparticle leads to lipid antigen persistence and memory differentiation of antigen-specific T cells
Published in eLife (25-10-2023)“…(Mtb) infection elicits both protein and lipid antigen-specific T cell responses. However, the incorporation of lipid antigens into subunit vaccine strategies…”
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Journal Article -
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Comorbid illnesses are associated with altered adaptive immune responses to SARS-CoV-2
Published in JCI insight (22-03-2021)“…Comorbid medical illnesses, such as obesity and diabetes, are associated with more severe COVID-19, hospitalization, and death. However, the role of the immune…”
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Cytotoxic T Cells Targeting Spike Glycoprotein Are Associated with Hybrid Immunity to SARS-CoV-2
Published in The Journal of immunology (1950) (01-05-2023)“…mRNA vaccination of individuals with prior SARS-CoV-2 infection provides superior protection against breakthrough infections with variants of concern compared…”
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MR1-restricted T cell clonotypes are associated with "resistance" to Mycobacterium tuberculosis infection
Published in JCI insight (08-05-2024)“…T cells are required for protective immunity against Mycobacterium tuberculosis. We recently described a cohort of Ugandan household contacts of tuberculosis…”
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6
Cytotoxic T cells targeting spike glycoprotein are associated with hybrid immunity to SARS-CoV-2
Published in The Journal of immunology (1950) (01-05-2023)“…Abstract mRNA vaccination of individuals with prior SARS-CoV-2 infection provides superior protection against breakthrough infections with variants of concern…”
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Journal Article -
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MR1-restricted T cell clonotypes are associated with resistance to Mycobacterium tuberculosis infection
Published in The Journal of immunology (1950) (01-05-2023)“…Abstract T-cells are a critical facet of the adaptive immune system and have been shown in both human and animal studies to be essential for control of…”
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8
Vaccination with mycobacterial lipid loaded nanoparticle leads to lipid antigen persistence and memory differentiation of antigen-specific T cells
Published in eLife (25-10-2023)“…Mycobacterium tuberculosis (Mtb) infection elicits both protein and lipid antigen-specific T cell responses. However, the incorporation of lipid antigens into…”
Get full text
Journal Article