Search Results - "Aguilar, Luis F"

Coumarin-Resveratrol-Inspired Hybrids as Monoamine Oxidase B Inhibitors: 3-Phenylcoumarin versus trans -6-Styrylcoumarin by Mellado, Marco, González, César, Mella, Jaime, Aguilar, Luis F, Celik, Ismail, Borges, Fernanda, Uriarte, Eugenio, Delogu, Giovanna, Viña, Dolores, Matos, Maria J

“…Monoamine oxidases (MAOs) are attractive targets in drug design. The inhibition of one of the isoforms (A or B) is responsible for modulating the levels of…”
Get full text

A pH-Sensitive Fluorescent Chemosensor Turn-On Based in a Salen Iron (III) Complex: Synthesis, Photophysical Properties, and Live-Cell Imaging Application by Nilo, Nicole, Reyna-Jeldes, Mauricio, Covarrubias, Alejandra A., Coddou, Claudio, Artigas, Vania, Fuentealba, Mauricio, Aguilar, Luis F., Saldías, Marianela, Mellado, Marco

“…pH regulation is essential to allow normal cell function, and their imbalance is associated with different pathologic situations, including cancer. In this…”
Get full text

Differential dynamic and structural behavior of lipid-cholesterol domains in model membranes by Aguilar, Luis F, Pino, José A, Soto-Arriaza, Marco A, Cuevas, Francisco J, Sánchez, Susana, Sotomayor, Carlos P

“…Changes in the cholesterol (Chol) content of biological membranes are known to alter the physicochemical properties of the lipid lamella and consequently the…”
Get full text

Resveratrol-Schiff Base Hybrid Compounds with Selective Antibacterial Activity: Synthesis, Biological Activity, and Computational Study by Sánchez-González, Rodrigo, Leyton, Patricio, Aguilar, Luis F, Reyna-Jeldes, Mauricio, Coddou, Claudio, Díaz, Katy, Mellado, Marco

“…Nowadays, antimicrobial resistance is a serious concern associated with the reduced efficacy of traditional antibiotics and an increased health burden…”
Get full text

Modernidad, Racionalidad, Efectividad: en conmemoración de Max Weber by Aguilar, Luis F

“…En conmemoración del centenario de la muerte de Max Weber, el artículo, compuesto por tres apartados, expone las ideas principales de su método sociológico,…”
Get full text

Bullfrogs (Lithobates catesbeianus) as a Potential Source of Foodborne Disease by Zepeda-Velazquez, Andrea P., Gómez-De-Anda, Fabián-Ricardo, Aguilar-Mendoza, Luis F., Castrejón-Jiménez, Nayeli Shantal, Hernández-González, Juan Carlos, Varela-Guerrero, Jorge A., de-la-Rosa-Arana, Jorge-Luis, Vega-Sánchez, Vicente, Reyes-Rodríguez, Nydia E.

“…•First report of diverse bacterial genera in bullfrogs for consumption in Mexico.•Detection of foodborne bacterial pathogens.•Identification of opportunistic…”
Get full text

Effects of phenylpropanolamine (PPA) on in vitro human erythrocyte membranes and molecular models by Suwalsky, Mario, Zambrano, Pablo, Mennickent, Sigrid, Villena, Fernando, Sotomayor, Carlos P., Aguilar, Luis F., Bolognin, Silvia

“…► PPA is a common ingredient in cough–cold medication and appetite suppressants. ► Reports on its effects on human erythrocytes are very scarce. ► We found…”
Get full text

Effects of cholesterol on lipid vesicle fusion mediated by infectious salmon anaemia virus fusion peptides by Tarnok, María Elena, Guzmán, Fanny, Aguilar, Luis F.

Get full text

The acetylcholinesterase (AChE) inhibitor and anti-Alzheimer drug donepezil interacts with human erythrocytes by Zambrano, Pablo, Suwalsky, Mario, Jemiola-Rzeminska, Malgorzata, Strzalka, Kazimierz, Sepúlveda, Benjamin, Gallardo, María J., Aguilar, Luis F.

“…Donepezil is used to treat symptomatically the Alzheimer's disease (AD). This drug is a specific inhibitor of the enzyme acetylcholinesterase (AChE), whose…”
Get full text

Combined 3D-QSAR and docking analysis for the design and synthesis of chalcones as potent and selective monoamine oxidase B inhibitors by Mellado, Marco, González, César, Mella, Jaime, Aguilar, Luis F., Viña, Dolores, Uriarte, Eugenio, Cuellar, Mauricio, Matos, Maria J.

“…[Display omitted] •QSAR methodologies are described as theoretical approaches to speed up drug discovery.•Docking calculations proved to be important tools to…”
Get full text

An in vitro study on the interaction of the anti-Alzheimer drug rivastigmine with human erythrocytes by Zambrano, Pablo, Suwalsky, Mario, Jemiola-Rzeminska, Malgorzata, Strzalka, Kazimierz, Aguilar, Luis F.

“…The inhibition of the enzyme acetylcholinesterase (AChE) is a frequently used therapeutic option to treat Alzheimer's disease (AD). By decreasing the levels of…”
Get full text

nueva gobernanza pública: un panorama conceptual by Aguilar Villanueva, Luis F.

“…La capacidad y efectividad directiva de los gobiernos democráticos es el marco de referencia de este artículo, que expone los motivos que causaron “el…”
Get full text

In vitro effects of the antitumor drug miltefosine on human erythrocytes and molecular models of its membrane by Petit, Karla, Suwalsky, Mario, Colina, José R., Aguilar, Luis F., Jemiola-Rzeminska, Malgorzata, Strzalka, Kazimierz

“…This study was aimed at elucidating the molecular mechanisms of the interaction of the antitumor alkylphospholipid drug miltefosine with human erythrocytes…”
Get full text

Inhibition of Caco-2 and MCF-7 cancer cells using chalcones: synthesis, biological evaluation and computational study by Mellado, Marco, Reyna-Jeldes, Mauricio, Weinstein-Oppenheimer, Caroline, Coddou, Claudio, Jara-Gutierrez, Carlos, Villena, Joan, Aguilar, Luis F.

“…Cancer is the second death cause worldwide, with breast and colon cancer among the most prevalent types. Traditional treatment strategies have several side…”
Get full text

In vitro antioxidant and antiproliferative effect of the extracts of Ephedra chilensis K Presl aerial parts by Mellado, Marco, Soto, Mauricio, Madrid, Alejandro, Montenegro, Iván, Jara-Gutiérrez, Carlos, Villena, Joan, Werner, Enrique, Godoy, Patricio, Aguilar, Luis F

“…Ephedra chilensis K Presl, known locally as pingo-pingo, is a Chilean endemic plant used in traditional medicine as an anti-inflammatory and used in other…”
Get full text

An in vitro study of the protective effect of caffeic acid on human erythrocytes by Colina, José R., Suwalsky, Mario, Manrique-Moreno, Marcela, Petit, Karla, Aguilar, Luis F., Jemiola-Rzeminska, Malgorzata, Strzalka, Kazimierz

“…The interaction and protective effect of caffeic acid (CA) on human erythrocytes (RBC) and molecular models of its membrane were studied. The latter consisted…”
Get full text

Carfilzomib as a potential inhibitor of NADH-dependent enoyl-acyl carrier protein reductases of Klebsiella pneumoniae and Mycobacterium tuberculosis as a drug target enzyme: insights from molecular docking and molecular dynamics by Mahfuz, A. M. U. B., Stambuk Opazo, Felipe, Aguilar, Luis F., Iqbal, Muhammad Nasir

“…Multiple antibiotic-resistant strains of Klebsiella pneumoniae can cause life-threatening infections. Bacterial enoyl-acyl carrier protein (ACP) reductases…”
Get full text

Sensitive fluorescent chemosensor for Hg(II) in aqueous solution using 4’-dimethylaminochalcone by Mellado, Marco, Roldán, Nicole, Miranda, Rodrigo, Aguilar, Luis F., Bravo, Manuel A., Quiroz, Waldo

“…Mercury (Hg) is an element with high toxicity, especially to the nervous system, and fluorescent pigments are used to visualize dynamic processes in living…”
Get full text

Toxic effects of the anticancer drug epirubicin in vitro assayed in human erythrocytes by Petit, Karla, Suwalsky, Mario, Colina, José R., Contreras, David, Aguilar, Luis F., Jemiola-Rzeminska, Malgorzata, Strzalka, Kazimierz

“…Epirubicin is a cytotoxic drug used in the treatment of different types of cancer and increasing evidence suggests that its target is cell membranes. In order…”
Get full text

Synthesis of fluorescent chalcones, photophysical properties, quantitative structure-activity relationship and their biological application by Mellado, Marco, Sariego-Kluge, Rafaela, Valdés-Navarro, Franco, González, César, Sánchez-González, Rodrigo, Pizarro, Nancy, Villena, Joan, Jara-Gutierrez, Carlos, Cordova, Claudio, Bravo, Manuel A., Aguilar, Luis F.

“…[Display omitted] •We synthesized eleven fluorescent chalcone with 4-(Dimethylamino)phenyl fragments.•The photophysical properties are linked to Molecular…”
Get full text